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robertmiles
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Re: WCG and Pandemic-Related Projects

It depends on how well treatment with that antibody works. It's best to also find more antibodies and a few vaccines just in case.
Wooow, 1st antibody is out. This is GOOD news biggrin ! But, does that mean we don't need to do anything with our machines? If so, disapppointed though not talking .

Folding@home is also working on the coronavirus and is out of GPU work for at least the last 5 or so hours since I first checked. I'm assuming it has to with the Nvidia Twitter account asking people to join with their GPUs (it has 3.6k RT's and 7.1k favs and I'm assuming, several million views).

Personally I don't think we need a project for this. There are already other projects working on this and the fact that it is a pandemic means there are tons of pharma companies, universities, labs, etc working on this. The 1st antibody has already been discovered - https://www.erasmusmagazine.nl/en/2020/03/14/...-antibody-against-corona/

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MattShizzle
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Re: WCG and Pandemic-Related Projects

We need everything we can to work on this. This is like a World War II level problem that needs all possible resources. We are looking at 10s of millions of people worldwide (if not, and I seriously hope not (won't say hope to god being an Atheist - over 100 million.) This is likely the worst thing any of us faced in our lifetimes.
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voidcomp
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Re: WCG and Pandemic-Related Projects

I'll remember that not unlike the candle industry who thought electricity was going to market too quickly.

Unlike the candle industry, bad pharmaceutical products can injure and kill the patients.
Past experiences showed us that shortcuts in this particular area can be devastating.


Try thinking outside the box for once and stop believing what was done yesterday has anything to do what what's going on now or the future.

Folding right now just announced they hit 1.5 exaFLOPS of computer processing, something unheard of in just the past few years ago. That's a bunch of power that can be spliced into any number of research arms.

Add to this a couple of common sense directives:

(1) Congress should instruct the FDA to publish vaccine trial data in real time

(2) Congress should extend liability protections to COVID-19 vaccine candidate manufacturers

(3) Create the mechanism by which patients can opt to forgo the protections of vaccine approval based on informed consent.

Streamline the process. FDA and NIH are acknowledging there's a ton needed for improvement. No risk no return with many many willing participants. The candle industry had its turn, time for modern medicine and technology to take over.
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[Edit 1 times, last edit by voidcomp at Mar 27, 2020 1:50:46 AM]
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KLiK
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Re: WCG and Pandemic-Related Projects

I seriously doubt Rosetta@home wants to become a WCG sub-project and if they aren't allowing Rosetta@home users to choose the work they get, why would they do that for WCG?

We need all hands on deck...so why now?

WCG can pick up only jobs with included names "*COVID-19*", check photo of jobs here:

& we can all select this "extra project" to participate in.

All we need now it to be "together", as there are no nations in this, no races, no sexes...all together as a human kind!
cool
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KerSamson
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Re: WCG and Pandemic-Related Projects

@voidcomp
I respect your opinion, nevertheless I don't share it.
Public healthcare is not "just thinking out of the box". The human body is complex, pharmacocinetics is complex, we do not have much experience and data with SARS-CoV-2.
Even if the situation is an emergency case, all of us - in particular scientists - need to remain careful and to work very accurately.
Look what happened with the dengue vaccine: good intention very bad outcome depending of the patient previous disease.
It is not because something seems to work, that it shall be used everywhere for everybody without thinking.
On my side - and I live in currently the worst impacted area (beside Italy and Spain) between France and Switzerland - I would like to understand the mechanisms of this pandemy. Beside looking for cures, it is important as well to understand as quick as possible how this disease really work. If we understand better how it works, we will be able to cure it better and smoother.
The question is really not to "think out of the box" but to do really good scientific work in order to avoid to make the current situation worst as it already is.
Quick and dirty come never good out at the story end.
Cheers,
Yves
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jackielan2000
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China
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Re: WCG and Pandemic-Related Projects

@voidcomp
I respect your opinion, nevertheless I don't share it.
Public healthcare is not "just thinking out of the box". The human body is complex, pharmacocinetics is complex, we do not have much experience and data with SARS-CoV-2.
Even if the situation is an emergency case, all of us - in particular scientists - need to remain careful and to work very accurately.
Look what happened with the dengue vaccine: good intention very bad outcome depending of the patient previous disease.
It is not because something seems to work, that it shall be used everywhere for everybody without thinking.
On my side - and I live in currently the worst impacted area (beside Italy and Spain) between France and Switzerland - I would like to understand the mechanisms of this pandemy. Beside looking for cures, it is important as well to understand as quick as possible how this disease really work. If we understand better how it works, we will be able to cure it better and smoother.
The question is really not to "think out of the box" but to do really good scientific work in order to avoid to make the current situation worst as it already is.
Quick and dirty come never good out at the story end.
Cheers,
Yves


I completely agree with you. In this situation, what we need mostly are science and logic. I saw so many people, so many countries do not show any respect and fear to this virus so that their action is dumb and illogical.

Finding cure or vaccine is not the most important task at the moment. We can defeat it without using a cure or a vaccine. The influenza virus of 1918 never returned. No drug or vaccine was ever produced for it. At the moment, it would be great to crunch out a cure but it would be stupid and dangerous to find sth with devestating side-effect and use it en mass.

I'm Chinese, living in Beijing. We've been having no new case for more than 20 days here. I've been out working since this Monday and feeling pretty safe, even though we still wear masks.

I wish all of you guys well and get out of this mass quickly.
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Jim1348
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Re: WCG and Pandemic-Related Projects

This is likely the worst thing any of us faced in our lifetimes.

Not yet. At the moment, 27,000 people have died. That is a relatively small number for a major disease. It gets worse depending on how fast it spreads, and how well it is controlled (or isn't). That isn't just a question of crunching numbers on a PC, but social control and commitment. And how much economic hardship are you willing to forego to save so many lives? Even the weather will play a role.

Many of the cases are relatively mild; look at Boris Johnson and Prince Charles, just to name some obvious notables. Once a significant proportion of the population has been exposed, then a degree of herd immunity will set in and the new infection rate decrease. We don't know when that will happen. Intelligent management is probably more effective in the short run than any vaccine or treatment we will get soon. More testing and face masks and gloves will do more good than more PC projects in the short term.
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[Edit 1 times, last edit by Jim1348 at Mar 27, 2020 11:47:43 PM]
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yoerik
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Re: WCG and Pandemic-Related Projects

This is likely the worst thing any of us faced in our lifetimes.

Not yet. At the moment, 27,000 people have died. That is a relatively small number for a major disease.


It's not right to trivialize tragic deaths - but this is by far not the worst thing any of us have faced as a collective society. Staying calm and rational during this pandemic, is important too. 100% agreed.
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Aurum
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The Great Basin
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Re: WCG and Pandemic-Related Projects

The influenza virus of 1918 never returned.

Except in 1919 when it killed millions more.

BTW, victims buried in permafrost still harbor viable virus.
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...KRI please cancel all shadow-banning
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[Edit 1 times, last edit by Aurum420 at Mar 28, 2020 4:20:51 PM]
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KerSamson
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Re: WCG and Pandemic-Related Projects

Regarding the Permafrost issue, it is probably one of the biggest healthcare challenge for the next decades.
Just to put facts in perspective: in 1968/1969, it was the last strong influenza epidemy. Just during this particular Winter, 30'000 people died only in France (at this time, about 50 million inhabitants), I do not have the global figures.
Today, we are luckily far away from such high rate.
Nevertheless, we need to be very careful and to fight as much as possible.
Yves
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