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Re: Interesting News Articles About Cancer

Study supports concerns over meat additive-cancer link

03-Aug-2010
Related topics: Science & Nutrition, Meat, fish and savoury ingredients, Preservatives and acidulants
A new epidemiological study has reported modest support for suggestions that some components in processed meat may increase risk of bladder cancer.
Consumption of red- and processed meat has previously been linked to an increased risk of developing certain types of cancer, and animal studies have indicated that certain compounds could be behind the purported link.
These compounds include nitrites and nitrates, which are added to processed meats as preservatives and to enhance colour and flavour and break down into N-nitroso compounds, as well as heterocyclic amine, polycyclic aromatic hydrocarbons.................
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Re: Interesting News Articles About Cancer

The latest articles from BMC Cancer, published between 07-Jul-2010 and 05-Aug-2010

BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials. BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus, Current Contents, CABI, Thomson Reuters (ISI) and Google Scholar.

Featured articles

Epigenetics change neuroblastoma phenotype
BMC Cancer 2010, 10:286
Tumorigenic LA1-55n neuroblastoma cells have higher levels of promoter methylation and lower levels of expression of tumor suppressor function genes indicating that epigenetic changes contribute to neuroblastoma phenotype.
Calretinin a promising mesothelioma marker
BMC Cancer 2010, 10:242
A two-site enzyme-linked immunosorbent assay is highly sensitive and detects increased levels of calretinin in malignant mesothelioma patients, indicating that it could be a potential minimally invasive diagnostic test for this tumor.
Cruciferous vegetables may fight lung cancer
BMC Cancer 2010, 10:162
Increasing consumption of raw cruciferous vegetables significantly reduces the risk of lung cancer for smokers, particularly for former smokers, indicating that phytochemicals uniquely present in these vegetables could have cancer-protective effects.
Treatment disparities in breast cancer
BMC Cancer 2010, 10:154
In British Columbia, Chinese women with early stage breast cancer are significantly more likely to receive surgery without radiation than South Asian or Iranian women, indicating the need for guiding interventions to reduce ethnic disparities.
Mutation profiling for colon cancer
BMC Cancer 2010, 10:101
High-throughput mass spectrometric SNP genotyping can rapidly identify mutations common to colon cancer in routinely-processed formalin-fixed paraffin-embedded tissue samples.....
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Re: Interesting News Articles About Cancer

Vaccine Injection Targeted in Building a Better ‘Bull’s-Eye’ to Fight Prostate Cancer

Clinical Trial Exploring New Treatment Combination Opens at The Cancer Institute of New Jersey

New Brunswick, N.J.– Looking to harness the body’s own immune system to target prostate cancer that has spread to the bones (metastatic) and is unresponsive to standard treatment, investigators at The Cancer Institute of New Jersey (CINJ) have just launched a clinical trial focusing on a combination of vaccine and radiation drug therapy. The goal is to see if disease progression will be further delayed by adding two different experimental injections to the standard treatment. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.
A standard treatment for prostate cancer that has spread to the bones is with a drug approved by the Food and Drug Administration known as samarium153. It contains material that gives off a tiny amount of energy (radiation) that damages cancer cells. And because radiation drugs such as samarium153 also can increase the immune system’s ability to find and kill cancer cells, CINJ researchers want to combine this treatment with a series of vaccination injections aimed at helping the body’s natural defenses work better.....
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[Edit 1 times, last edit by Former Member at Aug 7, 2010 12:30:36 PM]
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Re: Interesting News Articles About Cancer

Robotic prostatectomy gains momentum as new study shows low complication rate

Research by Investigators at The Cancer Institute of New Jersey Published in Journal of Endourology
While sharp debate continues among medical professionals as to whether a radical prostatectomy performed with the assistance of a robotic device is more beneficial than the traditional open surgery method, research just published by investigators at The Cancer Institute of New Jersey (CINJ) shows new evidence supporting the safety of the robotic procedure – including what is believed to be one of the lowest complication rates to date. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School..........
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Re: Interesting News Articles About Cancer

UCLA researchers discover protein that shuttles RNA into cell mitochondria

Researchers at UCLA's Jonsson Comprehensive Cancer Center and the departments of Chemistry and Biochemistry and Pathology and Laboratory Medicine have uncovered a role for an essential cell protein in shuttling RNA into the mitochondria, the energy-producing "power plant" of the cell.
The import of nucleus-encoded small RNAs into mitochondria is essential for the replication, transcription and translation of the mitochondrial genome, but the mechanisms that deliver RNA into mitochondria remain poorly understood.
In the current study, UCLA scientists show a new role for a protein called polynucleotide phosphorylase (PNPASE) in regulating the import of RNA into mitochondria. Reducing the expression of PNPASE decreased RNA import, which impaired the processing of mitochondrial genome-encoded RNAs. Reduced RNA processing inhibited the translation of proteins required to maintain the electron transport chain that handles oxygen to produce energy in the form of adenosine triphosphate, the energy currency of a cell. With reduced PNPASE, unprocessed mitochondrial RNAs accumulated, protein translation was inhibited and energy production was compromised, leading to stalled cell growth...........
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Re: Interesting News Articles About Cancer

New Cancer Radiation Technology Improves Accuracy, Drops Treatment Time in Select Patients


The Department of Radiation Oncology at the University of Alabama at Birmingham Comprehensive Cancer Center is among the world's first to begin using radiation technology that dramatically reduces treatment times.
UAB's Hazelrig-Salter Radiation Oncology Center is the third U.S. site to acquire TrueBeam technology. TrueBeam, by Varian Medical Systems Inc., can complete a standard 40-minute radiation therapy in less than a minute for select patients. The precision of the instrument, measured in increments of less than a millimeter, comes from real-time patient imaging, positioning, beam shaping and many other data points synchronized continually as treatment progresses.........
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Re: Interesting News Articles About Cancer

The Cancer Genome Workbench: Identifying and Visualizing Complex Genetic Alterations in Tumors

We present the Cancer Genome Workbench (CGWB), a web-based tool (http://cgwb.nci.nih.gov) that integrates and displays the genome-wide collection of somatic mutation, copy number alteration, gene expression and methylation data generated by a number of projects including The Cancer Genome Atlas (TCGA), the Sanger Center's COSMIC initiative, NHGRI's Tumor Sequencing Project (TSP), NCI's Therapeutically Applicable Research to Generate Effective Treatment (TARGET), Johns Hopkins University and GlaxoSmithKline Cancer Cell Line Genomic Profiling Data. Using examples from the TCGA glioblastoma multiforme (GBM) data set, we describe the utility of viewers such as the CGWB heatmap and genome browser views. We also present the use of the CGWB to evaluate the significance of regulatory processes such as methylation and microRNA expression in controlling gene expression. The integrated views of multiple data types enable a user to evaluate whether molecular data is consistent across platforms as well as to examine the correlation between different data types such as somatic DNA alterations and gene expression. Confidential data such as clinical data and individual genotypes are available to certified users who have been approved by project-specific regulatory bodies such as the TCGA Data Access Committee. We include use case scenario examples using the recently incorporated next-generation sequencing data from the TCGA ovarian serous cystadenocarcinoma data set. The rich collection of multiple-platform, high-resolution genomic data available on the CGWB will aid the discovery of the complex molecular mechanisms that underlie numerous cancers........
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Re: Interesting News Articles About Cancer

Advance toward earlier detection of melanoma

Scientists are reporting development of a substance to enhance the visibility of skin cancer cells during scans with an advanced medical imaging system that combines ultrasound and light. The hybrid scanner could enable doctors to detect melanoma, the most serious form of skin cancer, in its earliest and most curable stages, the report in the monthly journal ACS Nano indicates......

Skin Tumor
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Re: Interesting News Articles About Cancer

Australia corals to light up cancer cure fight

Australian scientists have discovered a cluster of brilliant shallow-water corals that could help in the search for anti-cancer drugs and to understand global warming, a researcher said Saturday.
The vividly fluorescent cluster was found in waters off Lord Howe Island, 600 kilometres (400 miles) east of the Australian mainland, with some displaying rich reds that were difficult to find and in high demand for studies of cancer cells, researcher Anya Salih said.
"The underwater buttresses and caverns are densely inhabited by hundreds of corals, all deeply pigmented by the most intense green, blue and many with red fluorescence," she said.......
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Re: Interesting News Articles About Cancer

NCSU Study To Help Understand Nanoparticles Inside the Body

Just where do those used up cancer killers go when they're done?


Though nanoparticles are being hailed by many as the future of science -- an imminent revolutionary evolution in everything from medicine to energy to construction -- it is still poorly understood how nanoparticles will get along with biological systems like the human body over the course of time . Previous studies have shown that nanoparticles can slip into the body through skin and numerous other uses in medicine involve injecting doped particles directly into the blood stream. But where do they end up once their usefulness is expended and how or do they even get eliminated from the body?.................
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