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World Community Grid Forums
Category: Active Research
Forum: OpenPandemics - COVID-19 Project
Thread: Covid-19 - Discuss Scientific Papers |
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Thread Status: Active Total posts in this thread: 80
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robertmiles
Senior Cruncher US Joined: Apr 16, 2008 Post Count: 443 Status: Offline Project Badges: 
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Study finds hydroxychloroquine helped coronavirus patients survive better A surprising new study found that the controversial antimalarial drug hydroxychloroquine helped patients survive better in the hospital. Not very new. More recent studies have already shown that the side effects cause more deaths than not using it at all. |
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Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
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WHO halts hydroxychloroquine trials after failure to reduce deaths
Robert, Thanks I agree. I just think that seeing the scientific paper is important. https://www.who.int/news-room/detail/04-07-20...eatment-arms-for-covid-19  |
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Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
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Comparing SARS-CoV2 with SARS-CoV and influenza pandemics - The Lancet Infectious Diseases
This paper compares transmissibility, hospitalization, and mortality rates for severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) with those of other epidemic coronaviruses, such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory coronavirus (MERS-CoV), and pandemic influenza viruses. https://doi.org/10.1016/S1473-3099(20)30484-9 |
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robertmiles
Senior Cruncher US Joined: Apr 16, 2008 Post Count: 443 Status: Offline Project Badges:
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An article claiming that hydroxychloroquine can help control COVID-19 safely, but only if used with a zinc supplement.
It says that the main thing hydroxychloroquine does in this treatment is to help the zinc get into the cells, and therefore toxic doses are not needed. The zinc acts on the virus instead. This is NOT a scientific paper, but it still suggests something for the scientists to test. Distorting science in the COVID pandemic https://drmalcolmkendrick.org/2020/07/05/dist...ce-in-the-covid-pandemic/ |
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robertmiles
Senior Cruncher US Joined: Apr 16, 2008 Post Count: 443 Status: Offline Project Badges:
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There is a scientific paper on this, although not yet peer-reviewed.
COVID-19 Outpatients – Early Risk-Stratified Treatment with Zinc Plus Low Dose Hydroxychloroquine and Azithromycin: A Retrospective Case Series Study https://www.preprints.org/manuscript/202007.0025/v1 |
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robertmiles
Senior Cruncher US Joined: Apr 16, 2008 Post Count: 443 Status: Offline Project Badges:
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Genomewide Association Study of Severe Covid-19 with Respiratory Failure
https://www.nejm.org/doi/full/10.1056/NEJMoa2020283 |
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Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
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Research in the Context of a Pandemic
The current literature on the treatment of coronavirus disease 2019 (COVID-19) is filled with anecdotal reports of therapeutic successes in clinical trials with small numbers of patients and observational cohort studies claiming efficacy with little regard to the effect of unrecognized confounders. For the field to move forward and for patients' outcomes to improve, there will need to be fewer small or inconclusive studies and more studies such as the dexamethasone trial now reported by RECOVERY Collaborative Group in the Journal. https://www.nejm.org/doi/full/10.1056/NEJMe2024638?query=NC |
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Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
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Audio Interview: New SARS-CoV-2 Vaccine Results, with Peter Piot / NEJM
On July 29, 2020, the editors of The New England Journal of Medicine are joined by Peter Piot, M.D., Ph.D. who talks about his own experience with Covid-19, as well as recent developments in SARS-CoV-2 vaccines. https://www.nejm.org/doi/full/10.1056/NEJMe2026514?query=TOC |
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Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
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Black/African American Communities are at Highest Risk of COVID-19: Spatial Modeling of New York City ZIP Code-Level Testing Results
----------------------------------------Areas with large proportions of Black/African American residents are at markedly higher risk that is not fully explained by characteristics of the environment and preexisting conditions in the population. https://www.medrxiv.org/content/10.1101/2020.05.14.20101691v2 [Edit 1 times, last edit by Jim Slade at Aug 11, 2020 12:19:54 PM] |
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Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
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Social Network Analysis of COVID-19 Sentiments: Application of Artificial Intelligence
The aim of this study is to analyze discussions on Twitter related to COVID-19 and to investigate the sentiments toward COVID-19. This study identified 5 prevalent themes of COVID-19 discussion with sentiments ranging from positive to negative. These themes and sentiments can clarify the public's response to COVID-19 and help officials navigate the pandemic. https://www.jmir.org/2020/8/e22950/ |
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