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[CSF] Thomas Dupont
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News XXVII

Mettre fin à l’épidémie d’ici à 2030 reste possible

"C’est l’un des objectifs fixés à l’issue de la 34ème réunion du Conseil de Coordination du Programme de l’ONUSDA de Genève qui vient de s’achever : Mettre fin à l’épidémie de sida d’ici à 2030, inclure la prévention du VIH dans les objectifs de développement durable dès 2015 et élargir la protection sociale des personnes vivant avec le VIH. Des objectifs atteignables, selon l’Onusida qui comprennent, outre la réduction de 90% des décès liés au Sida d’ici à 2030, la lutte contre la stigmatisation et contre la discrimination. A condition de trouver les financements nécessaires."

http://www.santelog.com/news/VIH-sida-VHC/sid...relasuite.htm#lirelasuite
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[CSF] Thomas Dupont
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News XXVIII

1- Causes of death shifting in people with HIV

"HIV-positive adults in high income countries face a substantially reduced risk of death from AIDS-related causes, cardiovascular disease, and liver disease compared with a decade ago, according to a large international study. Although deaths from most causes declined over the study period, there was no reduction in death rates from non-AIDS cancers which remained stable over time (1.6 deaths per 1000 years 1999-2000 to 2.1 in 2009-2011). Non-AIDS cancers are now the leading cause of non-AIDS deaths in people with HIV, accounting for 23% of all deaths."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

2- Next step in creating HIV-1 immunotherapy using fossil virus

"An antibody that can neutralize the HIV-1 fossil virus has been discovered by researchers. This may lead to finding a viable immunotherapy option for HIV-1. The research team found that the right antibody directed against an ancestral fossil virus buried within everyone's genomes might be able to target HIV-1 and neutralize it."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

3- Research on persons with HIV/AIDS not taking medication, not engaged in care

"A new study describes factors believed to contribute to the critical public health issues of persons with HIV/AIDS not complying with treatment or care. The study has a particular focus on African American and Latino/Hispanic people with HIV/AIDS, the racial/ethnic groups most affected by HIV/AIDS."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29
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[CSF] Thomas Dupont
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News XXIX

1- Predicting which HIV patients will respond better to future therapeutic vaccine

"HIV patients with a higher level of a particular biomarker, or a measurable indicator found in the blood, may respond more favorably to an experimental immune activating vaccine, a study suggests. Experts believe the findings might lead to a more customized vaccine for certain patients, which potentially might permit them to come off antiretrovirals, drugs used to treat HIV."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

2- Why the immune system fails to kill HIV

"Our immune system contains CD8+ T cells which protect us from various diseases such as cancer and viruses. Some of them are specifically tasked with killing cells infected with the HIV virus – and researchers have for the first time identified a key explanation for why these cells are unsuccessful in their task. In simple terms, the immune system's ignition keys have not been turned all the way to the start position, which would enable the CD8+ T cells to kill the cells infected with HIV."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29
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[CSF] Thomas Dupont
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News XXX

1- New HIV prevention recommendations combine biomedical, behavioral approaches

"In an innovative approach to HIV prevention, an interdisciplinary group of experts has come together for the first time to lay out a framework of best practices to optimize the role of the clinician in achieving an AIDS-free generation. The recommendations are intended as guidelines for clinicians to implement a combined biomedical-behavioral approach to HIV care and prevention. They are based on a comprehensive review of data that was either published or presented at scientific conferences over the past 17 years."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

2- Offering option of initial HIV care at home increases use of antiretroviral therapy

"Offering adults in Malawi optional home initiation of care following HIV self-testing resulted in a significant increase in the proportion of adults initiating antiretroviral therapy (ART) compared with standard HIV care, a study indicates. "At a time when universal test and treat approaches to controlling the HIV epidemic are being considered, home initiation of HIV care shows high promise as a simple strategy to improve the uptake of ART when HIV self-testing is carried out at home," a researcher noted."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

3- Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients

"In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study. In human immunodeficiency virus (HIV) infection, abdominal fat accumulation is associated with ectopic (out of place) fat accumulation in the liver. Nonalcoholic fatty liver disease (NAFLD) may progress to end-stage liver disease and liver cancer."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

4- Effect on pregnancy of receiving antiretroviral therapy for prevention of HIV

"Among heterosexual African couples in which the male was HIV positive and the female was not, receipt of antiretroviral pre-exposure preventive (PrEP) therapy did not result in significant differences in pregnancy incidence, birth outcomes, and infant growth compared to females who received placebo, according to a study."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

5- Combination treatment for hep C associated with favorable response among HIV patients

"HIV-infected patients also infected with hepatitis C virus (HCV) who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study. Up to 7 million persons worldwide are infected with both human immunodeficiency virus (HIV) and hepatitis C virus."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

6- Study examines incentives to increase medical male circumcision to help reduce risk of HIV in Kenya

"Among uncircumcised men in Kenya, compensation in the form of food vouchers worth approximately U.S. $9 or $15, compared with lesser or no compensation, resulted in a modest increase in the prevalence of circumcision after 2 months, according to a study. "There was a significant increase in uptake among married and older participants, groups that have been harder to reach previously. The interventions also significantly increased the likelihood of circumcision uptake among participants at higher risk of acquiring HIV," the authors write."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29
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[CSF] Thomas Dupont
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News XXXI

INFOGRAPHIE. Comment le SIDA infecte l'organisme

"La conférence internationale sur le SIDA, qui a débuté le 20 juillet 2014 en Australie, est l'occasion de revenir sur la manière dont le VIH infecte nos cellules."

http://www.sciencesetavenir.fr/sante/20121130...e-l-organisme#xtor=EPR-6-[ActuSciences17h]-20140721
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[CSF] Thomas Dupont
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News XXXII

Le virus constitue ses réservoirs avant de commencer à circuler

"Cette étude d’efficacité du traitement anti-VIH (SIV) chez les singes rhésus nous en apprend sur la vitesse de développement de l’infection ici à SIV (virus de l'immunodéficience simienne) le virus similaire au VIH, mais chez le singe. Si l’on sait que les niveaux d'infection dans le sang peuvent être bien gérés grâce à la thérapie antirétrovirale (TARV), l’étude révèle la rapidité de formation des réservoirs viraux, dans les tout premiers jours de l’infection, bien avant que le virus ne soit détectable dans le sang. Ces travaux, publiés dans la revue Nature, ajoutent ainsi encore au défi des stratégies de lutte contre le VIH."

http://www.santelog.com/news/VIH-sida-VHC/vih...relasuite.htm#lirelasuite

The virus constitutes its reservoirs before beginning to circulate

"This study of the effectiveness of anti-HIV therapy (SIV) in rhesus monkeys tells us the rate of development of infection by SIV (simian immunodeficiency virus) the virus similar to HIV, but in monkeys . If it is known that infection levels in the blood can be well managed with antiretroviral therapy (ART), the study reveals rapid formation of viral reservoirs in the first few days of infection, although before the virus is detectable in the blood. This work, published in the journal Nature, adds to the challenge and still control strategies against HIV."

http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13594.html

French Article
http://www.santelog.com/news/VIH-sida-VHC/vih...relasuite.htm#lirelasuite
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[CSF] Thomas Dupont
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News XXXIII

1- HIV, malaria, and tuberculosis: Success of the Millennium shown in most comprehensive study to date

"Accelerated progress against the global burden of HIV, malaria, and tuberculosis (TB) has been made since 2000 when governments worldwide adopted Millennium Development Goal 6 to combat HIV/AIDS, malaria, and TB. New estimates from a major new analysis show that worldwide, the number of people living with HIV has risen steadily to around 29 million people in 2012. The data also show that malaria is killing more people than previously estimated, although the number of deaths has fallen rapidly since 2004. Progress for TB looks promising."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29

2- Control of HIV pandemic will not be achieved without radical improvement in support for sex workers

"Across the world, in high- and low-income countries, women, men, and transgender people who sell sex are subjected to repressive and discriminatory law, policy, and practice, which in turn fuel human rights violations against them, including violence and discrimination. All of these factors are preventing sex workers from accessing the services which they need in order to effectively prevent and treat HIV infection, according to a major new Series on HIV and sex workers."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29
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[CSF] Thomas Dupont
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News XXXIV

19 millions de vies sauvée par les antirétroviraux

"C'est la conclusion d'une étude présentée à l'occasion de la conférence internationale sur le SIDA qui se tient actuellement en Australie."

http://www.sciencesetavenir.fr/sante/20140723...-les-antiretroviraux.html

19 million lives saved by antiretroviral

"This is the conclusion of a study presented at the International Conference on AIDS held currently in Australia."

http://www.thelancet.com/series/HIV-and-sex-workers

French Article
http://www.sciencesetavenir.fr/sante/20140723...-les-antiretroviraux.html
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News XXXV

On pourrait en finir avec l'épidémie dans 15 ans

"Le nombre de décès dus au Sida dans le monde a chuté de plus de 30 % en 10 ans, tout comme le nombre de nouvelles infections par le VIH, laissant espérer une extinction de l'épidémie d'ici à 2030, a indiqué mercredi l'Onusida."

http://www.futura-sciences.com/magazines/sant...l-epidemie-dans-15-ans%5D
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News XXXVI

Combination antiretroviral therapy helps treat HCV in patients co-infected with HIV

"Treatment of HIV patients co-infected with the hepatitis C virus (HCV) with an anti-retroviral drug therapy not only tackles HIV, but also reduces HCV replication, according to a new study."

http://www.sciencedaily.com/releases/2014/07/...ily%3A+Top+Health+News%29
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