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jhindo
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Re: Exciting breakthrough in the fight against childhood cancer!

benaji, all the research supported by World Community Grid and our wonderful volunteers is conducted out of public or non-profit research institutions. And all projects are required to make the data generated on World Community Grid publicly available to the wider scientific community. Some projects do so while the project runs on World Community Grid (e.g. the Human Proteome Folding project published their data on a regular basis, and the Clean Energy Project published the first 2+ million results last summer while the project continues its work on World Community Grid). Other research teams wait until the project has completed its work on World Community Grid, they analyze the results, publish their findings and then publish the data. Either way, once that data is published, other researchers are free to use it for their own research. In this way, World Community Grid supports open science by making that information freely available to all.

However, the steps to go from a promising drug candidate to an actual approved drug are lengthy and very costly, which is where pharmaceutical backing often becomes essential in that lifecycle as typically research organizations would not be able to fund the entire drug development process.

Hope that clarifies the extent to which research is non-profit and our ongoing commitment to supporting open science.
[Mar 31, 2014 2:58:56 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Former Member
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Re: Exciting breakthrough in the fight against childhood cancer!

benaji, all the research supported by World Community Grid and our wonderful volunteers is conducted out of public or non-profit research institutions. And all projects are required to make the data generated on World Community Grid publicly available to the wider scientific community. Some projects do so while the project runs on World Community Grid (e.g. the Human Proteome Folding project published their data on a regular basis, and the Clean Energy Project published the first 2+ million results last summer while the project continues its work on World Community Grid). Other research teams wait until the project has completed its work on World Community Grid, they analyze the results, publish their findings and then publish the data. Either way, once that data is published, other researchers are free to use it for their own research. In this way, World Community Grid supports open science by making that information freely available to all.

However, the steps to go from a promising drug candidate to an actual approved drug are lengthy and very costly, which is where pharmaceutical backing often becomes essential in that lifecycle as typically research organizations would not be able to fund the entire drug development process.

Hope that clarifies the extent to which research is non-profit and our ongoing commitment to supporting open science.


Thanks for clarification, I didnt mean to suggest that this project wasnt nonprofit.its a great thing this project has done.
I think his point was that he wished drugs could get to people cheaply because of wcg.
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[Edit 1 times, last edit by Former Member at Mar 31, 2014 5:36:43 PM]
[Mar 31, 2014 4:33:57 PM]   Link   Report threatening or abusive post: please login first  Go to top 
jhindo
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Re: Exciting breakthrough in the fight against childhood cancer!

Thanks benaji :)

While we have no influence on the end price of a drug, the fact that researchers get access to this vast computing power is in itself a significant cost saving to researchers. Since research organizations rarely have access to the kind and scale of computing power provided by World Community Grid volunteers, the alternative would be relying on more traditional lab testing methods to screen drug candidates - which requires a significant investment. Instead, our researchers get to screen millions of these candidates (in Chiba's case, 3 million candidates screened in just a couple of years) so that only the most promising candidates need to proceed to expensive lab testing.
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Re: Exciting breakthrough in the fight against childhood cancer!

So, what do you think? Would it be feasible and desirable to create a "World Funding Grid" platform in order to finance research projects by the public?

Basically it would be something similar to kickstarter.com. However unlike kickstarter the World Funding Grid would be focused on carefully selected research projects financed either entirely or almost entirely by the public. The system would be similar to World Community Grid. The only difference would be that instead of donating free computing power to research projects, people could donate money.
[Apr 15, 2014 11:53:18 AM]   Link   Report threatening or abusive post: please login first  Go to top 
branjo
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Re: Exciting breakthrough in the fight against childhood cancer!

And who is going to administrate such money? Another charity? Existing one? No thank you. CMO.
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[Apr 15, 2014 1:29:19 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Exciting breakthrough in the fight against childhood cancer!

.................... The only difference would be that instead of donating free computing power to research projects, people could donate money.

....and it would be better coming from you if you actually did some work here at WCG, you have not done any for 9 months or so!

Total Run Time (y:d:h:m:s) (Rank) 0:025:04:51:43 (#378,847)
Points Generated 151,912 (#218,957)
Results Returned (Rank) 254 (#255,410)
Avg. Run Time Per Calendar Day (y:d:h:m:s) 0:000:00:53:03
Avg. Run Time Per Result (y:d:h:m:s) 0:000:02:22:53
Average Points Per Hour of Run Time 251.15
Avg. Points Per Calendar Day 222.09
Avg. Points Per Result 598.08
Avg. Results Per Calendar Day 0.37
Last Result Returned (UTC) 13/08/13 19:41:03 [5,873+ hour(s) ago]
Device Installations 7
Registered Member Since 06/01/2012
[Apr 15, 2014 1:34:16 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Former Member
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Re: Exciting breakthrough in the fight against childhood cancer!

I don't know anything about financial processes but somehow platforms like kickstarter managed to solve the "money administration"-problem. Because if they weren't able to solve it then platforms like kickstarter simply wouldn't exist.

(What does 'CMO' stand for?)
[Apr 16, 2014 5:52:47 PM]   Link   Report threatening or abusive post: please login first  Go to top 
branjo
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Re: Exciting breakthrough in the fight against childhood cancer!

Well, "the platforms" like KS take something like 30% of revenues money eyes . Do your homework humanXYZ prior posting such nonsenses.

CountMeOut
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Crunching@Home since January 13 2000. Shrubbing@Home since January 5 2006

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[Edit 1 times, last edit by branjo at Apr 16, 2014 8:03:56 PM]
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Former Member
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Re: Exciting breakthrough in the fight against childhood cancer!

I guess that those who have never heard of results from non-profit crunching being sold for profit have also never heard of Predictor. It used to be at Scripps, San Diego, until it was sold and moved.
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Re: Exciting breakthrough in the fight against childhood cancer!

Hello Misfit,
Predictor was distributed computing - not non-profit computing. There have been a broad range of funding models used in distributed computing. The normal method is based on government grants which pay for the servers. WCG is funded by IBM with contractual obligations ( https://secure.worldcommunitygrid.org/research/viewSubmitAProposal.do ) on each project for public domain release of results. This is described as non-profit, since it works out that way, but calling it public domain computing would probably be a more precise description.

Lawrence
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