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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Do you think that this could translate into a HIV cure at some point?
http://www.gizmag.com/experimental-treatment-for-ebola-virus/15261/ |
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duncanr
Cruncher UK Joined: Nov 25, 2005 Post Count: 7 Status: Offline Project Badges:
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When will there be a cure? I hate having to take the drugs to keep this virus under control.
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Dan60
Senior Cruncher Brazil Joined: Mar 29, 2006 Post Count: 185 Status: Offline Project Badges:
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Good question. I hope our crunching work will set us free from this villain... the sooner the better :o)
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GIBA
Ace Cruncher Joined: Apr 25, 2005 Post Count: 5374 Status: Offline |
I hope that with the several advances in many biomedics areas which we watch everday more, we will probably have a way to cure HIV soon.
----------------------------------------But it is my humble personal bet... Meanwhile, I and my team will keep focused on crunch FA@H in WCG to try help it in some way... ![]()
Cheers ! GIB@
![]() Join BRASIL - BRAZIL@GRID team and be very happy ! http://www.worldcommunitygrid.org/team/viewTeamInfo.do?teamId=DF99KT5DN1 |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
I am sure that there will be a cure for HI at some point, but not any time soon.
There are two reasons: The first is, that medicine is still not about healing but giving the body support to heal itself. Pharmacy is still a discipline of alchemy as we can see in this project: it is about mingling of substances and see what happens; nowadays on a very sophisticated and large scale level, though. There will be only suppressants for HI but no cure, unless we really grasp viruses as biological automata and treat them accordingly: There must be vital genetic sequences unique to the HIV, which cannot be changed without rendering the HIV disfunctional. These snippets must be found in those human cells responsible for the development of the HIV by some molecular testing device and rendered harmless. Either by encoding a "stop" signal into the sequence or by destroying the cell by e.g. marking this cell as "ill" to let the immune system destroy it. In other words we have to invent a particle that acts very much like the HIV: targeting the same cells, looking for evidence of a HIV infection and finally manipulating the cell to make it work in our favour. Understanding the HIV and its molecular mechanism lies far in the future. Single substances like Aspirin will certainly not do it. And this is the second problem: No COE in the world is able to explain his/her shareholders why they should invest billions into research in order solve this quickly. Besides, it must be obvious that a cure brings more profit than some life-long treatment. Moreover, once a cure would be found, all starvelings of this world would call for gratis treatment. So economy mechanism do not work in favour for a cure. And countries? Well, the German government for example decided to launch a scientific programm as "great national effort" with the aim - brace yourselves - to reach the moon! (not even manned but with probes, no joke! I think it was the first victim of the recent austerity measures). Admittedly, it is still difficult to communicate in any western country why you want to cure the gay's pest. Aren't they "receiving in themselves that recompence of their error which was meet?" People react irritated if you tell them that about 45% of all HIV infected people are women. |
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Dan60
Senior Cruncher Brazil Joined: Mar 29, 2006 Post Count: 185 Status: Offline Project Badges:
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...a scientific programm as "great national effort" with the aim - brace yourselves - to reach the moon! just as a sci-fi attachment: Antibodies (The X-Files) here and here , a bit of hope. ![]() [Edit 2 times, last edit by Dan60 at Jul 31, 2010 9:50:16 PM] |
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GIBA
Ace Cruncher Joined: Apr 25, 2005 Post Count: 5374 Status: Offline |
I really would like to read some opinion about expectation of science world people, about this discussion of time to found a possible cure, based on recent advances and facts comproved around the world recently and that matters for the several fronts of effort to find a cure...
----------------------------------------Would be great read something, for instance, coming from one of the experts on HIV/AIDS like the scientists involved on this WCG project. Just a teaser to clarify more ours knowledges on that... Hope get luck on that ! ![]()
Cheers ! GIB@
![]() Join BRASIL - BRAZIL@GRID team and be very happy ! http://www.worldcommunitygrid.org/team/viewTeamInfo.do?teamId=DF99KT5DN1 |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
@GIBA
I guess scientists of this area are very careful with predictions, as there were too many claims like "a cure for aids will be achieved within the next 2 years". I can only repeat what I have written before: the community is fishing in murky waters. They have not understood and even less mastered the biochemical mechanisms: E.g.: experiment 33 is 'screening the "Asinex library" of over 360,000 different fragments'(description of Experiment 33 on fightaidsathome.org). Undoubtedly, it is the best way we have for now, until considerable theoretical progress is made. We are all hoping for the jackpot. Maybe some ingenious trick will do it and we won't need all the theoretical depth, but this is all speculation. Now and then, we hear about promising headways in the media, but we have to bear in mind, that there is a lot of publicity involved: Different teams of researchers are competing for money. The easier the message, the more likely someone with money gets it and may fund a project. Not to mention journalists browsing around in articles far beyond their knowledge and bluntly quoting everything they've heard through the grapevine. And again: Most of the funding is not aimed at a cure, but at prophylaxis and suppressants. This is where the profit comes from. I have just read about this vaginal cream in clinical tests: it statistically reduces new infections (no cure!) by 39%. The news article is titled: 'New Vaginal Cream May Help Prevent HIV Infection In Women' (wordpress.com). I'd call this ballyhoo... and Russian roulette. You may want to ask directly someone from the TSRI (fightaidsathome.org). If you have any news, I would be more than happy to hear it. It is not that I am against a cure. I rather want to point out, why we do not find one. A lot of this inability to find a cure has to do with funding and therefore with politics. And a lot of this is, if not secretly desired, then at least accepted. Going to Mars/Moon and fighting wars over oil and saving banks with billions is considered more important. |
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Dan60
Senior Cruncher Brazil Joined: Mar 29, 2006 Post Count: 185 Status: Offline Project Badges:
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“If you want to activate latent HIV,” he explains, “you’ve got to activate all the host [cells] that have latent virus in them. Since you don’t know which ones are infected, the approach taken in the past has basically been to activate all CD4 [memory] cells.”
However, he says, “the immune system is not designed to work with every cell getting activated at the same time. People go into shock basically. It’s called a cytokine storm. So that’s not a good way [to activate latent HIV], because people can die.” Once again, as I keep on reading the news about possible HIV erradication, this seems to be the way: get at the reservoir of inactive HIV ![]() |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
I believe we will at least have a workable vaccine for aids.Like Dr Alex said we still have a lot to learn.
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