| Index | Recent Threads | Unanswered Threads | Who's Active | Guidelines | Search |
 |
World Community Grid Forums
Category: Completed Research
Forum: FightAIDS@Home
Thread: A possible FightAIDS@Home project (Fight the HIV's Vif protein)? |
| No member browsing this thread |
|
Thread Status: Active Total posts in this thread: 4
|
|
| Author |
|
|
Dan60
Senior Cruncher Brazil Joined: Mar 29, 2006 Post Count: 185 Status: Offline Project Badges: 
|
It's known that a human protein, the APOBEC3G, would naturally neutralize the HIV infection if a HIV protein called Vif wouldn't neutralize APOBEC3G (see the whole explanation at http://www.amfar.org/cgi-bin/iowa/td/feature/record.html?record=118 ).
I thought this would be a good idea: to find, through FightAIDS@Home, the best way to neutralize such Vif protein and set APOBEC3G free. |
||
|
|
vlsi0n
Cruncher Joined: Feb 14, 2006 Post Count: 1 Status: Offline Project Badges: 
|
This sounds good, I'm wondering why no one else has responded yet?
|
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Currently we are focused solely on HIV-Protease - we could still explore future phases with HIV-Protease (and more if we used different chemical databases)
Beyond that, there are a number of other protein targets including (but not limited to): HIV Integrase, HIV gp41, Deoxyhypusine Synthase, HIV gp120, Rab9 GTPase, and Nef protein Haven't heard of the one you mentioned but it is certainly an interesting prospect!  |
||
|
|
Sekerob
Ace Cruncher Joined: Jul 24, 2005 Post Count: 20043 Status: Offline |
Many hits on Google for this and even a Wiki:
----------------------------------------http://en.wikipedia.org/wiki/APOBEC3G Research can only build on prior research, thus as we complete this project, phase 2 foreseeably in early February 07, new knowledge will have been gained to decide on the next best course of action... phase 3 maybe.... it all depends on whether a strategy has or can be developed to attack it in the mass Distributed Computing environment. thanks for sharing this
WCG
----------------------------------------Please help to make the Forums an enjoyable experience for All! [Edit 1 times, last edit by Sekerob at Nov 21, 2006 8:57:45 AM] |
||
|
|
|