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Michael2901
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Re: Interesting News Articles About Cancer

http://www.bio-medicine.org/biology-news-1/He...y-news+%28Biology+News%29

Date:6/20/2013

"Herding cancer cells to their death

June 20, 2013, New York, NY and Oxford, UK An advanced tumor is a complex ecosystem. Though derived from a single cell, it evolves as it grows until it contains several subspecies of cells that vary dramatically in their genetic traits and behaviors. This cellular heterogeneity is what makes advanced tumors so difficult to treat. Publishing their findings in today's online issue of Cancer Cell, an international team of scientists led jointly by Professors Colin Goding from the Ludwig Institute for Cancer Research who is based at the University of Oxford and Jos Neptuno Rodriguez-Lpez from the University of Murcia, Spain describe a therapeutic strategy that manipulates a mechanism driving that heterogeneity to treat advanced melanoma. Their preclinical studies show that the strategy, which employs a new drug-like molecule in combination with an existing chemotherapy, is highly specific to melanoma cells and effective against tumors that resist all other therapies..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/262311.php

"Article Date: 24 Jun 2013

Outcome Of Experimental Chlamydia Infections Points Towards Cancer

Chlamydia trachomatis is a human pathogen that is the leading cause of bacterial sexually transmitted disease worldwide with more than 90 million new cases of genital infections occurring each year. About 70 percent of women infected with Chlamydia remain asymptomatic and these bacteria can establish chronic infections for months, or even years. Even when it causes no symptoms, Chlamydia can damage a woman's reproductive organs. In addition, standard antibacterial drugs are proving increasingly ineffective in complete eradication, as Chlamydia goes in to persistent mode, leading to asymptomatic chronic infection. Researchers at the Max Planck Institute for Infection Biology in Berlin (MPIIB) now show that Chlamydia infections can cause mutations in the host DNA by overriding the normal mechanisms by which their host prevents unregulated growth of genetically damaged cells that pave the way for the development of cancer..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/262317.php

"Article Date: 24 Jun 2013

Virus Combination Effective Against Deadly Brain Tumor, Moffitt Cancer Center Study Shows

A combination of the myxoma virus and the immune suppressant rapamycin can kill glioblastoma multiforme, the most common and deadliest malignant brain tumor, according to Moffitt Cancer Center research. Peter A. Forsyth, M.D., of Moffitt's Neuro-Oncology Program, says the combination has been shown to infect and kill both brain cancer stem cells and differentiated compartments of glioblastoma multiforme..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/262342.php

"Article Date: 25 Jun 2013

Men Who Can't Produce Sperm Face Increased Cancer Risk, Stanford-Led Study Finds

Men who are diagnosed as azoospermic - infertile because of an absence of sperm in their ejaculate - are more prone to developing cancer than the general population, a study led by a Stanford University School of Medicine urologist has found. And a diagnosis of azoospermia before age 30 carries an eight-fold cancer risk, the study says..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/262364.php

"Article Date: 25 Jun 2013

Targeting Antioxidant Enzymes With Novel Therapeutics May Selectively Kill Off Metastasizing Cancer Cells

A new study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. The findings may suggest a chemotherapeutic approach to prevent the spread of cancers..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/articles/263561.php

"Article Date: 18 Jul 2013

Breakthrough prostate cancer treatment

Researchers have developed a new treatment for advanced prostate cancer that has spread to the bones, which delivers a "high-energy" burst of radiation to cancer cells, according to a study published in the New England Journal of Medicine.

The phase III trial, conducted by researchers at The Royal Marsden NHS Foundation Trust and scientists from The Institute of Cancer Research in the UK, studied 921 men suffering from prostate cancer..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/articles/262475.php

"Article Date: 25 Jun 2013

How Safe Is Splenda (Sucralose)?

Splenda (sucralose) is being downgraded from "safe" to "caution" after an Italian animal study linked sucralose to a higher risk of developing leukemia. The Center for Science in the Public Interest (CSPI) says it awaits the Italian study's review before deciding what long-term safety grade to assign to Splenda in its Chemical Cuisine guide to food additives..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/articles/262486.php

"Article Date: 26 Jun 2013

Advanced Prostate Cancer Treatment Usage Rising Fast In Low Risk Patients

More men with low-risk prostate are undergoing advanced treatment, including robotic prostatectomies and intensity-modulated radiotherapy, even though their risk of non-cancer mortality is much higher, researchers from University of Michigan, Ann Arbor, reported in JAMA (June 26th 2013 issue).

The authors added that these low-risk prostate cancer patients will likely not benefit from advanced treatment technologies.

Several studies have shown that "watchful waiting" does not result in higher mortality among older men with low-risk prostate cancer. An article published in Annals of Internal Medicine earlier this month showed that observation is better and cheaper for prostate cancer patients with low-risk, localized disease than undergoing immediate treatment..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/262440.php

"Article Date: 26 Jun 2013

Breast Cancer Stem Cells Destroyed By Targeted Viral Therapy In Preclinical Experiments

A promising new treatment for breast cancer being developed at Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine (VIMM) has been shown in cell culture and in animal models to selectively kill cancer stem cells at the original tumor site and in distant metastases with no toxic effects on healthy cells, including normal stem cells. Cancer stem cells are critical to a cancer's ability to recur following conventional chemotherapies and radiation therapy because they can quickly multiply and establish new tumors that are often therapy resistant..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/262442.php

"Article Date: 26 Jun 2013

Hunger For Amino Acids Makes Brain Cancer More Aggressive

To fuel phases of fast and aggressive growth, tumors need higher-than-normal amounts of energy and the molecular building blocks needed to build new cellular components. Cancer cells therefore consume a lot of sugar (glucose A number of tumors are also able to catabolize the amino acid glutamine, an important building block of proteins. A key enzyme in amino acid decomposition is isocitrate dehydrogenase (IDH). Several years ago, scientists discovered mutations in the gene coding for IDH in numerous types of brain cancer. Very malignant brain tumors called primary glioblastomas carry an intact IDH gene, whereas those that grow more slowly usually have a defective form..."
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