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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250537.php

Article Date: 24 Sep 2012

"Obese People Can Be Metabolically Healthy And In Good Shape

A person can be obese and metabolically healthy at the same time, which means that this person will have the same mortality risk for heart disease or cancer as people of normal weight. This is the conclusion of a study published in the prestigious journal European Heart Journal [1].

"Obesity is associated with a large number of chronic diseases as heart diseases or cancer. However, there is a group of obese people that do not suffer the metabolic complications associated with obesity", the author of the study, Prof. Francisco B.Ortega, explains.

Prof. Ortega is currently working as a researcher and professor at the University of Granada Department of Physical Education, and at the Karolinska Institut Department of BioSciences and Nutrition in Sweden. Prof. Ortega conducted this study during his professional stay at the University of South Carolina (USA), in collaboration with Prof. Steven N. Blair, one of the most renowned researchers in the world in the field of physical activity, fitness and health. Prof. Blair is the coordinator of the Aerobics Center Longitudinal Study (ACLS), which includes more than 43,000 people followed-up either for 15 years or until their death,

Prof. Ortega et al. observed in their study that between 30-40% of obese patients were metabolically healthy. "We made two findings: firstly, metabolically-healthy obese people exhibited better cardiorespiratory fitness - or aerobic fitness. Secondly, this subgroup has a lower mortality risk rate for heart disease or cancer than other obese people, and has the same mortality risk than people of normal weight."...
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250559.php

"Article Date: 24 Sep 2012

Camptothecin Analog FL118 Shown To Inhibit Production Of Key Cancer Survival Genes

Some 500,000 people die of cancer in the United States each year, often because their cancers have become resistant to approved therapies. Scientists at Roswell Park Cancer Institute (RPCI) have made headway in the effort to overcome resistance to treatment, publishing findings about a novel cancer drug that has been shown to inhibit several genes associated with the ability of cancer cells to survive and reproduce.

A team led by Fengzhi Li, PhD, Associate Professor of Oncology in RPCI's Department of Pharmacology and Therapeutics, assessed the antitumor effects of FL118, a camptothecin analog that is structurally similar to irinotecan and topotecan, in preclinical studies..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250617.php

"Article Date: 24 Sep 2012

Unexpected New Way To Produce Nylon Discovered During Cancer Research

In their quest for a cancer cure, researchers at the Duke Cancer Institute made a serendipitous discovery -- a molecule necessary for cheaper and greener ways to produce nylon.
The finding, described in the journal Nature Chemical Biology, arose from an intriguing notion that some of the genetic and chemical changes in cancer tumors might be harnessed for beneficial uses..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/articles/250684.php

"Article Date: 25 Sep 2012

Cancer Deaths Expected To Drop 17% By 2030

Cancer death rates are predicted to drop by 17% (16.8) in the UK by 2030, according to Cancer Research UK's new report.
This new research coincides with a study from February of this year, which revealed that in 2012, the rates of deaths from cancer (per 100,000 people, by age) have decreased..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250667.php

"Article Date: 26 Sep 2012

Bladder Cancer Patients May Benefit From Anti-Androgen Therapy, Similar To That Used In Prostate Cancer

Bladder cancer patients whose tumors express high levels of the protein CD24 have worse prognoses than patients with lower CD24. A University of Colorado Cancer Center study published in the Proceedings of the National Academy of Sciences shows that CD24 expression may depend on androgens - and that anti-androgen therapies like those currently used to treat prostate cancer may benefit bladder cancer patients.

"This is a major finding - bladder cancer development and spread to other organs depends significantly on CD24, which in turn depends on androgens like testosterone. By taking away these androgens, we may be able to greatly diminish the proliferative and metastatic power of bladder cancer cells," says the study's senior author, Dan Theodorescu, MD, PhD, director of the University of Colorado Cancer Center..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/articles/250788.php

"Article Date: 27 Sep 2012

Stivarga (Rcoloegorafenib) Approved For Colorectal Cancer Treatment

Stivarga (regorafenib), a multi-kinase inhibitor, has been approved for the treatment of metastatic colorectal cancer that has continued to spread after treatment, the FDA (Food and Drug Administration) informed today. The medication is presented as tablets and taken orally.

Stivarga is a compound which was developed by Bayer Health Care and still belongs to the company. Bayer signed an agreement with Onyx Pharmaceuticals Inc. under which Onyx is given a royalty for any future worldwide net sales of Stivarga in oncology. Stivarga will be jointly promoted in the USA by Onyx and Bayer.

Stivarga blocks a number of enzymes which are involved in encouraging cancer growth. The medication was assessed by the FDA under its priority review program that reduces the approval process to six months. Priority review programs are assigned to drugs or treatments for which no adequate therapy currently exists, or compounds that offer major treatment advances..."
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Jim1348
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250617.php

"Article Date: 24 Sep 2012

Unexpected New Way To Produce Nylon Discovered During Cancer Research

In their quest for a cancer cure, researchers at the Duke Cancer Institute made a serendipitous discovery -- a molecule necessary for cheaper and greener ways to produce nylon.
The finding, described in the journal Nature Chemical Biology, arose from an intriguing notion that some of the genetic and chemical changes in cancer tumors might be harnessed for beneficial uses..."

Maybe they can use similar techniques to produce bio-fuels from cheap organic materials.
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250740.php

"Article Date: 28 Sep 2012

Tumors Of The Voice Box Can Safely Be Removed Through The Mouth By Robotic Surgery

Robotic surgery though the mouth is a safe and effective way to remove tumors of the throat and voice box, according to a study by head and neck cancer surgeons at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).

This is the first report in the world literature illustrating the safety and efficacy of transoral robotic surgery for supraglottic laryngectomy, the researchers say..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250805.php

"Article Date: 30 Sep 2012

The Immune System And Brain Tumors - Potential Breakthrough

In what could be a breakthrough in the treatment of deadly brain tumors, a team of researchers from Barrow Neurological Institute and Arizona State University has discovered that the immune system reacts differently to different types of brain tissue, shedding light on why cancerous brain tumors are so difficult to treat..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/250886.php

"Article Date: 30 Sep 2012

New Weapons In The Fight Against Cancer

Where are the most promising developments from first-in-human studies?

Several new first-in-man studies for drugs targeted against a range of cancers were released at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna.

"These studies represent our first glance at some of the drugs that may improve cancer treatment in coming years," said Prof Ahmad Awada, head of the medical oncology clinic at Jules Bordet Institute, Brussels, Belgium, chair of the ESMO 2012 Developmental Therapeutics track. "Today's findings highlight the ways that clinical research is working on cancer therapies that target specific molecular pathways within tumor cells and their microenvironment. At ESMO 2012 this year, interesting early reports will be presented on MEK-, MET- and HSP90 inhibitors as well as studies on drugs targeting EGFR and PI3K and agents active in ALK-positive lung cancer resistant to crizotinib. In addition, new immunotherapeutic strategies and new generations of hormonal agents were at the menu at this year's ESMO congress."...
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