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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
X-Ray Analysis Deciphers Master Regulator Important for Skin Cancer
Science Daily Reports: With the X-ray vision of DESY's light source DORIS, a research team from Hamburg and Iceland has uncovered the molecular structure of a master regulator central to the most deadly form of skin cancer, melanoma. The mutations in the master regulator not only play a role in the development of skin cancer, but also cause severe genetic diseases like the Tietz and Waardenburg syndromes that lead to deafness, skin and hair pigmentation defects, abnormal eye anatomy and altered vision. The transcription factor also plays a role in our hair turning grey with age and other age-related pigmentation alterations. http://www.sciencedaily.com/releases/2012/12/...3A+Latest+Science+News%29 |
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Coleslaw
Veteran Cruncher USA Joined: Mar 29, 2007 Post Count: 1343 Status: Offline Project Badges:
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http://www.france24.com/en/20121205-dogs-can-...-cancer-pilot-study-shows
----------------------------------------The test saw dogs achieve a 70-percent success rate identifying cancer from 120 breath samples, a result so "encouraging" that a two-year study 10 times larger will now take place, Errhalt said. ![]() ![]() ![]() ![]() |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges:
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In challenge to personalized cancer care, DNA isn't all-powerful. That finding, published online Thursday in Science, could explain why almost none of the new generation of "personalized" cancer drugs is a true cure, and suggests that drugs based on genetics alone will never achieve that holy grail.
http://www.reuters.com/article/2012/12/13/us-...dna-idUSBRE8BC19620121213 |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
This article by Casey Reearch says
When we originally recommended Celsion, we stated that the company was sitting on a multibillion-dollar opportunity. And we stand by that statement. However, just because something is eventually worth that amount does not mean it's bankable today as a short-term investment. So we try to keep our analysis narrowly focused on what can be directly counted on and measured. In Celsion's case, that's the Phase III treatment, Thermodox, and the one area in which it is being studied: primary liver cancer (HCC). Even just in this narrow band, however, we see the market opportunity for Celsion as in excess of $1 billion. HCC is one of the most deadly forms of cancer. It currently ranks as the fifth most-common solid tumor cancer, and it's quickly moving up. With the fastest rate of growth among all cancer types, HCC projects to be the most prevalent form of cancer by 2020. The incidence of primary liver cancer is nearly 30,000 cases per year in the US, and approximately 40,000 cases per year in Europe. But the situation worldwide is far worse, with HCC growing at approximately 750,000 cases per year, due to the high prevalence of hepatitis B and C in developing countries. The full article may be located at http://www.caseyresearch.com/articles/breakin...inner?ppref=CSR438ED1212A |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
New Way to Kill Lymphoma Without Chemotherapy: Golden Nanoparticle Starves Cancer Cell to Death
Science Daily reports: Northwestern Medicine® researchers discovered a new nanoparticle that acts like a secret double agent. It appears to the cancerous lymphoma cell like a preferred meal -- natural HDL. But when the particle engages the cell, it actually plugs it up and blocks cholesterol from entering. Deprived of an essential nutrient, the cell eventually dies. http://www.sciencedaily.com/releases/2013/01/...3A+Latest+Science+News%29 |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
UCI team finds new target for treating wide spectrum of cancers
UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. http://news.uci.edu/press-releases/uci-team-f...wide-spectrum-of-cancers/ A much more detailed technical explanation can be found at the link below: http://www.nature.com/ncomms/journal/v4/n1/full/ncomms2361.html |
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twilyth
Master Cruncher US Joined: Mar 30, 2007 Post Count: 2130 Status: Offline Project Badges:
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Nullomers kill cancer
----------------------------------------There's a much better article in New Scientist, but you need to subscribe. A nullomer is a variation on the monomer/polymer terminology. It's a sequence of amino acids (aka peptide or protein), in this case 5 aminos long that are not found in nature. The speculation was that there might be a reason for that. Maybe they were too dangerous or toxic. A couple hundred were synthesized and tested and 2 that were promising were tested on cancer cells. The October issue of the online journal Peptides will publish the first results of nullomer-based drugs. They show that these compounds kill breast and prostate cancer cells in the laboratory. More significantly, while their lethal effects on cancer cells increase over time, nullomer effects on normal cells decrease over time. “We have a long way to go, but we finally have proof that nullomers have biological effects that can benefit human health,” Hampikian said. ![]() ![]() |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Bioelectric Signals Can Be Used to Detect Early Cancer
Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower the incidence of cancerous cells by manipulating the electrical charge across cells’ membranes. http://www.newswise.com/articles/bioelectric-...ed-to-detect-early-cancer |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Small-molecule drug drives cancer cells to suicide
Nature reports: "Cancer researchers have pinned down a molecule that can kick-start the body’s own tumour-destroying systems, triggering cell death in cancerous but not healthy tissue in mice." http://www.nature.com/news/small-molecule-dru...-cells-to-suicide-1.12385 |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
UCLA Scientists create nanoscale vehicle to battle cancer without harming healthy cells
Researchers at UCLA have developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells. http://newsroom.ucla.edu/portal/ucla/tiny-cap...tively-treats-243192.aspx |
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