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Dan60
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Re: Interesting news articles about AIDS

"HIV Hides Out in Bone Marrow Cells...
... So why not use a medication to kill all those parent cells, thereby perhaps ridding the body of HIV?..."


http://www.nlm.nih.gov/medlineplus/news/fullstory_96115.html
[Apr 29, 2010 2:51:55 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Interesting news articles about AIDS

New HIV Model Suggests Killer T Cell for Vaccine

http://www.sciencedaily.com/releases/2010/04/100429082347.htm

how physicists and biologists from Xiamen University have been able to incorporate random patterns in the virus' mutation, and the way the virus responds to antibodies, into their model.

Gratifyingly, they have found that the new model, and the projections made by the new model for development of disease, mirror real-life, clinical behaviour of the virus.
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Re: Interesting news articles about AIDS

New Microscope Able to 'See' Atoms for First Time: Atomic Structure of Tiny Virus Imaged

http://www.sciencedaily.com/releases/2010/05/100504095216.htm

The study, the researchers say, demonstrates the great potential of cryo-electron microscopy, or Cryo-EM, for producing extremely high-resolution images of biological samples in their native environment.

"This is the first study to determine an atomic resolution structure through Cryo-EM alone,"
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Re: Interesting news articles about AIDS

New Insights Into the Mystery of Natural HIV Immunity: Findings May Have Implications for Designing Effective AIDS Vaccine

http://www.sciencedaily.com/releases/2010/05/100505133250.htm

A different scenario unfolds in people who have the HLA B57 gene. Using their computer model, Chakraborty and colleagues showed that, because those individuals' T cells are exposed to fewer self-peptides in the thymus, T cells with receptors that mediate strong binding to viral proteins via just a few important contacts are more likely to escape the thymus. This makes these T cells more cross-reactive to targeted HIV peptide mutants, because as long as those points in the viral proteins don't mutate, the T cells are still effective. The model also showed that once those T cells are released into the bloodstream, they can effectively attack HIV proteins, even when the virus mutates.
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Re: Interesting news articles about AIDS

New hope for HIV vaccine efforts

US researchers say they are a step closer to understanding why some people have natural protection against HIV.
They believe rare individuals who progress very slowly to Aids when infected make white blood cells that are better at fighting the virus...
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Dan60
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Re: Interesting news articles about AIDS

Scientists Unravel Secret of HIV Resistance
Gene that strengthens immune system may someday lead to vaccine, researchers say

http://www.nlm.nih.gov/medlineplus/news/fullstory_98421.html
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Re: Interesting news articles about AIDS

Top NIH Infectious Disease Expert: More Research Could Bring About a “Functional Cure” for HIV/AIDS

http://www.amfar.org/hill/article.aspx?id=8620

“The urgency is not over. We have an emergency in this country and an emergency around the world as it relates to HIV/AIDS,” said El-Sadr, whose presentation was titled “Unfinished Business.” “There’s a need to continue an ambitious, innovative, courageous research agenda.”
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Re: Interesting news articles about AIDS

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Re: Interesting news articles about AIDS

Mild-mannered metabolic helper rushes to fight invading viruses, researchers report

BOSTON, Mass. - Within cells, an ancient antiviral duo can deliver a one-two knockout to thwart invading viruses, report researchers who have just unmasked the cellular sidekick that throws the first punch. The findings mean scientists must rethink the design of antiviral immunity and how the body fends off viruses of all types, including influenza and HIV.

In the study, Children's Hospital Boston researchers found, mild-mannered organelles inside the cell known as peroxisomes can detect virus invasion signals and launch a limited antiviral offensive. Other organelles, the mitochondria, follow up with a more definitive antiviral counterattack
"This is the first demonstration that peroxisomes are involved in immunity," said Jonathan Kagan, staff scientist in the gastroenterology division and senior author of the paper published May 6 in the online journal Cell. "This work has implications for our understanding of how we interact with infectious viruses and even bacteria." .....
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Re: Interesting news articles about AIDS

New York Times Examines Global Fight Against HIV/AIDS

Several articles in the New York Times examine the global fight against HIV/AIDS. "Uganda is the first country where major clinics routinely turn people away" because they lack funding, the newspaper writes in an article that reports "money for [HIV/AIDS] treatment has stopped growing." According to the newspaper, "American officials who spoke on the condition of anonymity confirmed the financing freeze" in Uganda. The article explores reasons for the U.S. funding cap there, including corruption...
[May 12, 2010 12:24:26 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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