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World Community Grid Forums
Category: Completed Research
Forum: FightAIDS@Home
Thread: Interesting news articles about AIDS |
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Thread Status: Active Total posts in this thread: 1122
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Papa3
Senior Cruncher Joined: Apr 23, 2006 Post Count: 360 Status: Offline Project Badges: 
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http://www.newscientist.com/article/dn18088-o...urprising-new-tricks.html
[...] Most drugs work by binding to a receptor or other molecule on cells, triggering a biochemical change. But many bind to other receptors too, producing side effects that only show up after tests in animals or people. [...] Using published databases of interactions between small molecules, or "ligands", and potential targets, they used software to search for similarities in chemical structure between ligands and 3665 drugs either in use or under development. This yielded a list of nearly 4000 previously unknown potential targets. Some of these new targets might explain known side effects. The software predicted that the anti-nausea drug domperidone should also bind to a receptor that contributes to cardiac arrhythmia – one of the drug's side effects. Others point to new uses: the antihistamine mebhydrolin should block a receptor involved in Alzheimer's disease. [...] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Lifted travel ban a step forward in HIV/AIDS
Tuesday, November 3, 2009 1:38 PM CST GREENVILLE — President Obama’s order lifting the ban on people infected with HIV from entering the country could lead to a better understanding of the illness and more tolerance towards those who suffer from it, according to Mississippi HIV/AIDS advocates..... |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
UNAIDS
UNAIDS, the Joint United Nations Programme on HIV/AIDS, is an innovative joint venture of the United Nations family, bringing together the efforts and resources of ten UN system organizations in the AIDS response to help the world prevent new HIV infections, care for people living with HIV, and mitigate the impact of the epidemic. With its headquarters in Geneva, Switzerland, the UNAIDS Secretariat works on the ground in more than 80 countries worldwide. Coherent action on AIDS by the UN system is coordinated in countries through the UN theme groups, and the joint programmes on AIDS. Cosponsors include UNHCR, UNICEF, WFP,UNDP, UNFPA, UNODC, ILO, UNESCO, WHO and the World Bank. UNAIDS helps mount and support an expanded response to AIDS – one that engages the efforts of many sectors and partners from government and civil society... Interactive map: Towards universal access . |
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Papa3
Senior Cruncher Joined: Apr 23, 2006 Post Count: 360 Status: Offline Project Badges:
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http://www.google.com/hostednews/ap/article/A...fdYAfJ6xjVziJnUAD9BS5PBG0
AIDS is leading cause of death, disease for women GENEVA — In its first study of women's health around the globe, the World Health Organization said Monday that the AIDS virus is the leading cause of death and disease among women between the ages of 15 and 44. [...] |
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Papa3
Senior Cruncher Joined: Apr 23, 2006 Post Count: 360 Status: Offline Project Badges:
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http://news.bbc.co.uk/2/hi/health/8353229.stm
Scientists have found a way to disarm a protein thought to play a key role in leukaemia and other cancers. [...] Previous attempts to neutralise the protein had failed, leading experts to conclude it was effectively "undruggable". [...] They employed a state-of-the-art technique using chemical braces to mould protein snippets called peptides into specific three dimensional shapes. These "stapled" peptides are readily absorbed by cells, and are so tiny they can be deployed to alter gene regulation at specific sites. [...] When tested in mice it was found to limit the growth of cancer cells. [...] Researcher Professor Greg Verdine said: "Stapled peptides promise to significantly expand the range of what's considered 'druggable'. "With our discovery, we've declared open season on transcription factors and other intractable drug targets." [...] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
16 Nov 2009 AP: Cold virus may have foiled HIV vaccine test
Past exposure to adenovirus caused people to produce more T-cells http://www.msnbc.msn.com/id/33971878/ns/health-aids/ |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Vaccines on Horizon for AIDS, Alzheimer's, Herpes
'Golden era' could bring vaccines against AIDS, Alzheimer's and addictions within 5 years Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it. Many could be on the market in five years or less. Contrast that with five years ago, when so many companies had abandoned the vaccine business that half the U.S. supply of flu shots was lost because of contamination at one of the two manufacturers left.... |
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robertmiles
Senior Cruncher US Joined: Apr 16, 2008 Post Count: 443 Status: Offline Project Badges: 
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Some new research suggesting which protein to aim any HIV vaccine or attachment blocking research at:
----------------------------------------New findings suggest strategy to help generate HIV-neutralizing antibodies http://www.physorg.com/news177874714.html Suggests that it will need to aim specifically at trimers of this protein, and in ways that don't break up the trimer, to have much effect. [Edit 1 times, last edit by robertmiles at Nov 20, 2009 4:16:06 AM] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
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