| Index | Recent Threads | Unanswered Threads | Who's Active | Guidelines | Search |
 |
World Community Grid Forums
Category: Completed Research
Forum: OpenZika
Thread: Interesting News Articles About Zika |
| No member browsing this thread |
|
Thread Status: Active Total posts in this thread: 154
|
|
| Author |
|
|
Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges: 
|
CRISPR screen identifies gene that helps resist West Nile, Zika viruses
Researchers from the University of Texas Southwestern Medical Center led by John Schoggins, Assistant Professor of Microbiology, report in a study published in Nature Microbiology the first use of CRISPR genome-wide screening to identify a gene that helps resist flavivirus infection https://www.sciencedaily.com/releases/2018/09/180917191848.htm  |
||
|
|
littlepeaks
Veteran Cruncher USA Joined: Apr 28, 2007 Post Count: 748 Status: Offline Project Badges: 
|
Zika virus causes microcephaly by attacking stem cells in the fetal brain, on the other hand, Glioblastoma affects glial cells in the brain which are similar to fetal stem cells that Zika attacks. These observations led the scientists to try to develop altered Zika vaccine that attacks cancerous glial cells instead of brain stem cells.
The study showed that Zika vaccine shrunk the tumor size in mice suffering from glioblastoma without any neurological damage. This research gives hope in finding a cure for glioblastoma. Zika virus as a weapon against brain cancer |
||
|
|
BladeD
Ace Cruncher USA Joined: Nov 17, 2004 Post Count: 28976 Status: Offline Project Badges: 
|
Zika virus causes microcephaly by attacking stem cells in the fetal brain, on the other hand, Glioblastoma affects glial cells in the brain which are similar to fetal stem cells that Zika attacks. These observations led the scientists to try to develop altered Zika vaccine that attacks cancerous glial cells instead of brain stem cells. The study showed that Zika vaccine shrunk the tumor size in mice suffering from glioblastoma without any neurological damage. This research gives hope in finding a cure for glioblastoma. Zika virus as a weapon against brain cancer Wow, very exciting! |
||
|
|
l_mckeon
Senior Cruncher Joined: Oct 20, 2007 Post Count: 439 Status: Offline Project Badges:
|
Australian scientists genetically engineer Zika resistant mosquitoes.
The Aedes aegypti mosquito is the not only the biggest transmitter of the Zika virus, it is also the number one disease vector for dengue fever, a carrier of yellow fever and of course the big one, malaria. For this reason, scientists have been attempting to use genetic engineering to limit the damage for some time, though never in this way specifically. Dr Prasad Paradkar, a senior research scientist at CSIRO, explains to New Atlas. "This particular research is unprecedented in engineering a mosquito which completely blocks the virus and could be easily adapted to work for other viruses such as dengue." More at: https://newatlas.com/engineered-red-eyed-mosquito-zika/58371/ |
||
|
|
KLiK
Master Cruncher Croatia Joined: Nov 13, 2006 Post Count: 3108 Status: Offline Project Badges: 
|
Australian scientists genetically engineer Zika resistant mosquitoes. The Aedes aegypti mosquito is the not only the biggest transmitter of the Zika virus, it is also the number one disease vector for dengue fever, a carrier of yellow fever and of course the big one, malaria. For this reason, scientists have been attempting to use genetic engineering to limit the damage for some time, though never in this way specifically. Dr Prasad Paradkar, a senior research scientist at CSIRO, explains to New Atlas. "This particular research is unprecedented in engineering a mosquito which completely blocks the virus and could be easily adapted to work for other viruses such as dengue." More at: https://newatlas.com/engineered-red-eyed-mosquito-zika/58371/ Why didn't they engineer "to bite less"?   |
||
|
|
[VENETO] boboviz
Senior Cruncher Joined: Aug 17, 2008 Post Count: 183 Status: Offline Project Badges: 
|
Exscalate
Powered by CINECA’s Marconi supercomputer, EXSCALATE (EXaSCale smArt pLatform Against paThogEns) is accelerating the search for new drugs, setting a new record: a “chemical library” of 500 billion molecules, up to 30 biological targets evaluated simultaneously, with a processing capacity of more than 3 million molecules a second. The EXSCALATE platform’s first test field is the epidemiological crisis caused by the Zika virus, which to date is still lacking effective treatment. In this case EXSCALATE has identified molecules potentially capable of inhibiting 5 of the 7 viral proteins: NS5, NS1, NS2B/NS3, NS3 and the membrane protein. The most promising molecules identified through the Exscalate platform are now undergoing biological testing. The case study carried out on the Zika virus will be “open” to the international community and the results made public through the ANTAREX4ZIKA.eu website. |
||
|
|
QuantumEthos
Senior Cruncher Joined: Jul 2, 2011 Post Count: 336 Status: Offline Project Badges: 
|
"Causative agents of Acute Encephalitis Syndrome
1. Viruses are the main causative agents in AES cases, although other sources such as bacteria, fungus, parasites, spirochetes, chemicals, toxins, and noninfectious agents have also been reported over the past few decades. 2. Japanese encephalitis virus (JEV) is the major cause of AES in India (ranging from 5-35 percent). Nipah virus, Zika virus are also found as causative agents for AES. 3. Herpes simplex virus, Influenza A virus, West Nile virus, Chandipura virus, mumps, measles, dengue, Parvovirus B4, enteroviruses, Epstein-Barr virus and scrub typhus, S pneumoniae are the other causes of AES in sporadic and outbreak form in India." https://www.indiatoday.in/education-today/gk-...farpur-1550412-2019-06-17 https://www.worldcommunitygrid.org/research/viewSubmitAProposal.do I consider the lychee fruit being unripe a research topic in relation to curing the acute encephalitis syndrome (AES) Illness "A further 20 children have died from acute encephalitis syndrome (AES) in just 24 hours, bringing the total number of child fatalities caused by toxic lychee fruit in the Bihar state of eastern India to more than 100." Deaths rise from lychee-linked brain disease in India as 20 children die in just 24 hours STORY: https://on.rt.com/9wig RS https://science.n-helix.com |
||
|
|
Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges:
|
With measles and Ebola grabbing headlines, it is easy to forget the health panic of 2016, when Zika was linked to severe birth defects in thousands of Brazilian newborns whose mothers were infected while pregnant, striking fear across the country and much of the Americas. As health officials struggled to halt its spread, the virus galloped through Latin America and the Caribbean that spring and summer and eventually reached the United States, sickening more than 200 people in Florida and Texas and prompting countless travelers to cancel vacations in the tropics. Then, seemingly overnight, the epidemic evaporated and public attention moved on. But Zika, it turns out, did not vanish. “Zika has completely fallen off the radar, but the lack of media attention doesn’t mean it’s disappeared,” said Dr. Karin Nielson, a pediatric infectious disease specialist at U.C.L.A. who studies Zika’s impact in Brazil. “In some ways, the situation is a bit more dangerous because people aren’t aware of it.” https://www.nytimes.com/2019/07/02/health/zika-virus.html |
||
|
|
Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
|
Uncovering a Hidden Zika Outbreak in Cuba-NIH Director's Blog
When Brazilian health officials discovered four years ago that the mosquito-borne Zika virus could cause severe birth defects and other serious health problems, it prompted a major effort across the Americas to curb the infection by controlling mosquitoes and issuing travel advisories. By mid-2017, the hard work seemed to have paid off, and reports of new Zika infections had nearly stopped. But it turns out Zika may be tougher to control than once thought. New research shows that a large previously hidden outbreak of Zika virus disease occurred in Cuba, just when it looked like the worst of the epidemic was over. The findings suggests that the Zika virus can linger over long periods, and that mosquito control efforts alone may slow, but not necessarily stop, the march of this potentially devastating infectious disease. https://directorsblog.nih.gov/2019/09/03/unco...en-zika-outbreak-in-cuba/ |
||
|
|
Jim Slade
Veteran Cruncher Joined: Apr 27, 2007 Post Count: 664 Status: Offline Project Badges:
|
Transgenic Aedes aegypti Mosquitoes Transfer Genes into a Natural Population
To control the mosquito-borne diseases yellow fever, dengue, chikungunya, and Zika fevers, a strain of transgenically modified Aedes aegypti mosquitoes containing a dominant lethal gene has been developed. Approximately 450 thousand males of this strain were released each week for 27 months in Jacobina, Bahia, Brazil. https://www.ncbi.nlm.nih.gov/pubmed/31506595?dopt=Abstract |
||
|
|
|