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Category: Active Research
Forum: Mapping Cancer Markers Forum
Thread: The Cancer Daily News : Stay connected to the latest news |
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Thread Status: Active Total posts in this thread: 178
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
New research outlines promising therapies for small cell lung cancer
----------------------------------------"Two recent studies have the potential to advance treatments for small cell lung cell cancer (SCLC), researchers report. This aggressive form of lung cancer has seen no treatment advances in 30 years and “is a disease in urgent need of new drug therapies,” write the study’s authors." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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alged
Master Cruncher FRANCE Joined: Jun 12, 2009 Post Count: 2363 Status: Offline Project Badges: 
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News CXVI
----------------------------------------_________________________________________________________ Biologists find an early sign of cancer Patients show boost in certain amino acids years before diagnosis of pancreatic cancer. Anne Trafton | MIT News Office September 28, 2014 https://newsoffice.mit.edu/2014/early-sign-pancreatic-cancer-0928  |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
News CXVI _________________________________________________________ Biologists find an early sign of cancer Patients show boost in certain amino acids years before diagnosis of pancreatic cancer. Anne Trafton | MIT News Office September 28, 2014 https://newsoffice.mit.edu/2014/early-sign-pancreatic-cancer-0928 Early sign of pancreatic cancer identified by researchers "A sign of the early development of pancreatic cancer –- an upsurge in certain amino acids that occurs before the disease is diagnosed and symptoms appear -- has been identified by a team of researchers. Although the increase isn’t large enough to be the basis of a new test for early detection of the disease, the findings will help researchers better understand how pancreatic cancer affects the rest of the body." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Adding cediranib to chemotherapy improves progression-free survival for metastatic or recurrent cervical cancer, phase II trial shows
----------------------------------------"For patients with cervical cancer that has recurred after treatment or has spread elsewhere in the body, adding the experimental drug cediranib to standard chemotherapy improves tumor shrinkage and adds a modest improvement in progression-free survival, researchers report." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- Crizotinib treatment effective against ROS1-positive lung cancer, study suggests "Treatment with the targeted therapy drug crizotinib effectively halted the growth of lung tumors driven by rearrangements of the ROS1 gene in a small clinical trial." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 3- French studies measure benefits of colorectal cancer screening "The introduction of biennial colorectal cancer screening in a region of France increased the rate of diagnosis of high risk pre-cancerous adenomas (sometimes called polyps) by 89%, researchers have reported." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 4- Customizing chemotherapy in lung cancer: New phase II data reported "Measuring the expression levels of an enzyme involved in DNA synthesis can help predict the response of lung cancers to certain treatments, a Korean study has shown. In a randomized phase II study, researchers showed that patients whose lung cancers expressed low levels of an enzyme called thymidylate synthase experienced a greater benefit from treatment with the combination of pemetrexed and cisplatin than those whose tumors expressed high levels." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 5- Chemotherapy: Rolapitant reduces nausea and vomiting in phase III trial "Rolapitant reduces nausea and vomiting in patients receiving cisplatin-based chemotherapy, according to the results of a phase III trial." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 6- Second-line afatinib significantly improves progression-free survival in recurrent or metastatic head and neck cancer, phase III trial shows "The tyrosine kinase inhibitor afatinib significantly improved progression-free survival compared to methotrexate in patients with recurrent or metastatic squamous cell carcinoma of the head and neck after failure of platinum-based chemotherapy, the results of a phase III trial show." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 7- Anamorelin shown to improve appetite and body mass in patients with cancer anorexia-cachexia "A new drug, anamorelin, improves appetite and body mass in patients with advanced lung cancer who are suffering cancer anorexia and cachexia, according to phase III data." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 8- Cancer during pregnancy: chemotherapy and radiotherapy are safe for babies, studies suggest "Children who are exposed to chemotherapy or radiotherapy while in the womb suffer no negative impacts on mental or cardiac development, international studies have shown. “When chemotherapy is administered after the first trimester of pregnancy, we cannot discern any problems in the children,” says lead author of a study on the topic." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
Pertuzumab adds 16 months survival benefit to trastuzumab and chemotherapy treatment for HER2-positive metastatic breast cancer
----------------------------------------"Patients with HER2-positive breast cancer that has spread to other parts of their body live around 16 months longer if treated with a combination of pertuzumab, trastuzumab and chemotherapy compared to those treated with trastuzumab and chemotherapy alone, updated results from the CLEOPATRA study reveal." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 CANCER du SEIN HER2-positif : Perjeta prolonge de 16 mois la survie "L’autorisation « fast track » accordée dès 2013 par la Food and Drug Administration (FDA) à ce nouveau médicament, Perjeta® (pertuzumab), en traitement néoadjuvant, pour le cancer du sein de stade précoce HER2-positif, illustrait déjà ses résultats d’efficacité de phase II. Aujourd’hui, le laboratoire Roche, fabriquant du médicament, annonce une survie prolongée de 15,7 mois chez les patientes atteintes de cancer du sein métastatique HER2-positif avec Perjeta® en combinaison avec Herceptin et une chimiothérapie. Un grand progrès pour les patientes atteintes de cette forme particulièrement agressive de cancer du sein." http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Genetic modifier affects colon tumor formation
----------------------------------------"The adenomatous polyposis coli protein, which protects against colon cancer, has been the focus of recent study. Many experiments involve testing mice with APC mutations, which cause colon cancer, and seeing if any new drug compounds will work against the mutations." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- Trastuzumab should remain as standard of care for HER2-positive breast cancer, trial suggests "Analysis of more than 8,000 women who participated in the world’s largest study of two treatments for HER2-positive breast cancer reinforces other findings from the clinical trial showing that trastuzumab (Herceptin) should remain the standard of care for this cancer, says a researcher." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 3- Promising results shown with targeted approaches in subsets of non-small cell lung cancer "The BRAF inhibitor dabrafenib has significant anti-tumour activity in patients with advanced BRAF V600E mutant non-small cell lung cancer whose disease has progressed after chemotherapy, according to phase II data." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 4- New data on combination treatments for melanoma "Combination therapy with both BRAF inhibitor vemurafenib and MEK inhibitor cobimetinib achieves greater progression-free survival and response rates than vemurafenib plus placebo in BRAF-mutation positive melanoma, according to phase III data." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 5- Nivolumab shows signs of superior response rate compared to standard chemotherapy in advanced melanoma "The monoclonal antibody nivolumab achieves superior response rates and a longer duration of response than standard chemotherapy in patients whose melanoma has progressed after treatment with ipilimumab, according to phase III data." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
CANCER du SEIN : Un nouveau rôle de l'œstrogène identifié
----------------------------------------"Un nouveau mécanisme par lequel l’hormone œstrogène contribue à la pathogenèse du cancer du sein, c’est ce que vient de mettre à jour cette équipe de l’Université de l’Illinois. A travers une protéine spécifique, UPR, l'œstrogène prépare les cellules tumorales à se diviser à se développer et dans le cancer du sein positif à l’œstrogène, permet à la tumeur de résister aux médicaments. Ces travaux, présentés dans la revue Oncogène révèlent de nouvelles cibles et de nouveaux marqueurs d’efficacité des traitements." http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite New role for estrogen in pathology of breast cancer discovered "A previously unknown mechanism by which estrogen prepares cells to divide, grow and, in the case of estrogen-positive breast cancers, resist cancer drugs, has been discovered in a recent study. The researchers say the work reveals new targets for breast cancer therapy and will help doctors predict which patients need the most aggressive treatment." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 http://www.eurekalert.org/pub_releases/2014-09/uoia-sda092414.php French Article http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Disease decoded: Gene mutation may lead to development of new cancer drugs
----------------------------------------"The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly, researchers report." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- New blood test determines whether you have or are likely to get cancer "Early detection and the risk assessment of cancer as easy as a simple blood test, a new study suggests. "A blood test to detect cancer and determine one's risk for cancer is a game-changer," said one expert. "A test like this -- which is sophisticated in design and simple to perform -- could make effective cancer screening available in places where traditional medical technology might not be available."." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 3- Cancer therapy: Driving cancer cells to suicide "A new class of chemical compounds makes cancer cells more sensitive to chemotherapeutic drugs, researchers report. They have also pinpointed the relevant target enzyme, thus identifying a new target for anti-tumor agents." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 4- Genetic test would help cut bowel cancer spread, research suggests "Screening families of patients with bowel cancer for a genetic condition would cut their risk of developing bowel, womb, and ovarian cancers, new research has found. "It's critical that more lives are saved by ensuring people gain access to the screening surveillance they need, so that bowel cancer can be ruled out first, not last, in younger patients," researchers note." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 5- New discovery approach accelerates identification of potential cancer treatments "A new approach to discovering potential cancer treatments has been described by researchers that requires a fraction of the time needed for more traditional methods. The researchers have used their method to identify an antibody that stops breast cancer tumor growth in animal models, and they are investigating the antibody as a potential treatment in humans." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Fertility preservation option for young boys with cancer
----------------------------------------"Treatments for certain childhood cancers come with a high risk of sterility. A new research study for young boys is focused on fertility preservation and restoration." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 2- FDG-PET/CT shows promise for breast cancer patients younger than 40 "PET/CT imaging of patients younger than 40 who were initially diagnosed with stage I–III breast cancer resulted in change of diagnosis, a study shows. While guidelines recommend FDG-PET/CT imaging only for women with stage III breast cancer, it can also help physicians more accurately diagnose young breast cancer patients initially diagnosed with earlier stages of the disease." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 3- Eighty percent of bowel cancers halted with existing medicines "More than 80 percent of bowel cancers could be treated with existing drugs, an international team of scientists say at the conclusion of their study. The study found that medicines called 'JAK inhibitors' halted tumor growth in bowel cancers with a genetic mutation that is present in more than 80 per cent of bowel cancers. Multiple JAK inhibitors are currently used, or are in clinical trials, for diseases including rheumatoid arthritis, psoriasis, blood cancers and myeloproliferative disorders." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 4- What to anticipate after you've heard those dreaded words 'you have breast cancer' "A new article looks at breast cancer and provides insight on what a patient may anticipate. Breast cancer is a malignant tumor that starts in the breast. A malignant tumor is a group of cancer cells that can invade other parts of the body. For American women, breast cancer is the second most common cancer (second only to skin cancer). About 12 percent of women in the United States will battle invasive breast cancer at one point during their lifetime." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 5- Immunotherapy could stop resistance to radiotherapy "Treating cancers with immunotherapy and radiotherapy at the same time could stop them from becoming resistant to treatment, scientists report. Radiotherapy is a very successful treatment for many forms of cancer, but in cancer cells that it doesn't kill it can switch on a 'flag' on their surface, called PD-L1, that tricks the body's defences into thinking that cancerous cells pose no threat." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 6- 'Virtual breast' could improve cancer detection "A 'virtual breast' has been developed to help train clinicians in the use of ultrasound elastography. The advanced imaging technique holds promise for improving cancer detection, but only if the results are interpreted properly." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Discovery could prevent development of brain tumors in children
----------------------------------------"A mechanism that promotes the progression of medulloblastoma, the most common brain tumor found in children, has been discovered by researchers. The team found that a protein known as Sonic Hedgehog induces DNA damage causes the cancer to develop." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 2- Socioeconomic factors, fashion trends linked to increase in melanoma "Researchers explored extenuating factors, such as socioeconomic and fashion trends, that may have contributed to increased incidence of melanoma over the past century." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 3- Dog's epigenome gives clues to human cancer "The bond between humans and dogs is strong and ancient. Dogs and people share many aspects of life. The relationship between the two species has been studied by psychologists, anthropologists, ethnologists and also by genetic and molecular biologists. In this sense, dogs are a great model for understanding the causes of human diseases, especially cancer. Unlike other mammals used in research, dogs develop cancer spontaneously as humans do and cancer is the most common cause of death in this species. The dog genome has been sequenced, but we still don't know how it is controlled and regulated, what we call the epigenome." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 4- New molecule fights oxidative stress; May lead to therapies for cancer and Alzheimer's "Breathing oxygen helps the body create energy for its cells. As a result of the breathing process, reactive molecules called 'free radicals' are produced that often cause damage to proteins and genes found in cells. This damage is known as oxidative stress. Free radicals also have been linked to cancer, Alzheimer's and Parkinson's disease. Now, investigators have discovered a molecule that treats oxidative stress." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 5- 'Stealth' nanoparticles could improve cancer vaccines "Cancer vaccines have recently emerged as a promising approach for killing tumor cells before they spread. But so far, most clinical candidates haven't worked that well. Now, scientists have developed a new way to deliver vaccines that successfully stifled tumor growth when tested in laboratory mice. And the key is in the vaccine's unique stealthy nanoparticles." http://www.sciencedaily.com/releases/2014/10/...ily%3A+Top+Health+News%29 |
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