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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Role of hormone in response to ovarian cancer treatment
----------------------------------------"The results of an investigation into how we might better tailor therapy for ovarian cancer have been released. The goal of the study was to investigate the role of the hormone HE4 in modulating an ovarian cancer's response to hormones and hormonal therapies. HE4 is a biomarker that is elevated in ovarian cancer and is known to play a role in resistance to chemotherapy." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- Finding new genetic links to prostate cancer "23 new regions of the genome have been discovered that influence the risk for developing prostate cancer, according to a study. Prostate cancer is the most common non-skin cancer in American men. About 1 in 6 men will be diagnosed with the disease in his lifetime. Family history is the strongest risk factor. A man with one close relative, a brother or father with prostate cancer is twice as likely to develop the disease as a man with no family history of prostate cancer." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 3- Abnormal properties of cancer protein revealed in fly eyes "Mutations in the human retinoblastoma protein gene are a leading cause of eye cancer. Now, scientists have turned to fruit fly eyes to unlock the secrets of this important cancer gene. Since fruit flies are essentially tiny people with wings, in terms of genetics, these model organisms can play a key role in advancing human medicine." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 4- Five genes to predict colorectal cancer relapses "Five genes have been discovered differentially expressed in normal accompanying cells in colorectal tumors. Analysis of these genes could be used to classify colorectal tumors, predict the evolution of the patient and thus take appropriate clinical decisions to prevent relapses." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 5- Many throat cancer patients can skip neck surgery "Patients with human papillomavirus (HPV) -- the same virus associated with both cervical and head and neck cancer -- positive oropharyngeal cancer see significantly higher rates of complete response on a post-radiation neck dissection than those with HPV-negative oropharyngeal cancer, researchers report." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 6- Improved risk identification will aid fertility preservation in young male cancer patients "Investigators have found the chemotherapy dose threshold below which male childhood cancer survivors are likely to have normal sperm production. By clarifying which patients are at highest risk for reduced sperm production as adults, researchers expect the findings to eventually increase use of pre-treatment fertility preservation methods such as sperm banking." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 7- Benefit of endocrine therapy in elderly women with low risk hormone receptor positive breast cancer? "Treatment with endocrine therapy and radiation therapy as part of breast conservation is the current standard of care for women with hormone-receptor positive invasive breast cancer. A new study, however, shows that combination may not be necessary for all patient populations with the disease." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 8- Focus on treatment costs, value: Less radiation for elderly women with early breast cancer "In a healthcare climate where the costs of treatment are increasingly weighed against potential benefit, a study has found that radiation oncologists are using fewer or less-aggressive radiation procedures on elderly women with early-stage breast cancer." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Cancer cells adapt energy needs to spread illness to other organs
----------------------------------------"Cancer cells traveling to other sites have different energy needs from their “stay-at-home” siblings, which continue to proliferate at the original tumor site, researchers have discovered. Given that a cancer cell's unyielding ability to metastasize is the primary cause of cancer-related death, understanding how they successfully migrate can be lifesaving." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- New cancer drug target involving lipid chemical messengers "More than half of human cancers have abnormally upregulated chemical signals related to lipid metabolism, yet how these signals are controlled during tumor formation is not fully understood. Researchers report that TIPE3, a newly described oncogenic protein, promotes cancer by targeting these pathways." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Study questions accuracy of lung cancer screens in some geographic regions
----------------------------------------"FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common, a new study suggests. Misdiagnosis of lung lesions suspicious for cancer could lead to unnecessary tests and surgeries for patients, with additional potential complications and mortality." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- New approach aims to silence cancer 'survival genes' "A promising new approach for tackling colorectal cancer, the second most common cause of cancer-related death, is under development. The new method works by silencing cancer 'survival genes' and could potentially combat cancer through the selective killing of colorectal cancer cells without adverse effects on normal, non-cancer cells." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Bacterial 'communication system' could be used to stop, kill cancer cells, study finds
----------------------------------------"A molecule used as a communication system by bacteria can be manipulated to prevent cancer cells from spreading, a study has demonstrated. "During an infection, bacteria release molecules which allow them to 'talk' to each other," said the lead author of the study. "Depending on the type of molecule released, the signal will tell other bacteria to multiply, escape the immune system or even stop spreading."." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- A way to kill chemo-resistant ovarian cancer cells: Cut down its protector "Ovarian cancer is the most deadly gynecological cancer, claiming the lives of more than 50 percent of women who are diagnosed with the disease. A new study provides new insight into why ovarian cancer is often resistant to chemotherapy, as well as a potential way to improve its diagnosis and treatment." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 3- Less costly to screen for, treat early-stage lung than to treat late-stage lung cancer "The average cost to screen high-risk individuals for developing lung cancer with low-dose computed tomography plus the average cost of curative intent treatment, like surgery, is lower than the average cost to treat advanced stage lung cancer, which quite rarely results in a cure." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 4- New anti-cancer peptide vaccines and inhibitors developed "Two new anticancer peptide vaccines and two peptide inhibitors have been developed as part of a larger peptide immunotherapy effort. The vaccines and inhibitors are designed to target the HER-3 and IGF-1R receptors, which are over-expressed in cancers of the breast, pancreas, esophagus and colon." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 5- Most breast cancer patients who had healthy breast removed at peace with decision "More women with cancer in one breast are opting to have both breasts removed to reduce their risk of future cancer. New research shows that in the long term, most have no regrets. Researchers surveyed hundreds of women with breast cancer who had double mastectomies between 1960 and 1993 and found that nearly all would make the same choice again." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 6- Good news for young patients with a leukemia subtype associated with a poor prognosis "Adjusting treatment based on early response to chemotherapy made a life-saving difference to young patients with an acute lymphoblastic leukemia (ALL) subtype associated with a poor outcome, researchers have found. The results are good news for children and adolescents with Philadelphia chromosome-like ALL (Ph-like ALL), a subtype that until now was associated with a poor prognosis. Ph-like ALL accounts for as much as 15 percent of the most common pediatric cancer." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 7- New 'designer proteins' in fight against Alzheimer's, cancer "Scientists are lending Mother Nature a helping hand in fight against cancer and Alzheimer’s with the development of a new, more effective way to make amino acids. The new 'designer proteins' can be used to make more effective drugs with fewer side effects, they report." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 8- Immune system is key ally in cyberwar against cancer "Scientists who are fighting a cyberwar against cancer find that the immune system may be a clinician's most powerful ally. "Recent research has found that cancer is already adept at using cyberwarfare against the immune system, and we studied the interplay between cancer and the immune system to see how we might turn the tables on cancer," said a co-author of a the study." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Modified vitamin D shows promise as treatment for pancreatic cancer
----------------------------------------"A vitamin D-derivative makes tumors vulnerable to chemotherapy, a new study shows. By attacking a wound repair mechanism called fibrosis, the findings may also have implications for other tough-to-treat tumors, such as lung, kidney and liver cancer, researchers report." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- How the ends of chromosomes are maintained for cancer cell immortality "Maintaining telomeres is a requisite feature of cells that are able to continuously divide and also a hallmark of human cancer. Telomeres are much like the plastic cap on the ends of shoelaces -- they keep the ends of DNA from fraying. In a new study, researchers describe a mechanism for how cancer cells take over one of the processes for telomere maintenance to gain an infinite lifespan." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 3- Chemists recruit anthrax to deliver cancer drugs "With some tinkering, a deadly protein becomes an efficient carrier for antibody drugs, researchers have discovered. "Anthrax toxin is a professional at delivering large enzymes into cells," says one researcher. "We wondered if we could render anthrax toxin nontoxic, and use it as a platform to deliver antibody drugs into cells."." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 4- Simple blood test could be used as tool for early cancer diagnosis "High levels of calcium in blood, a condition known as hypercalcemia, can be used by GPs as an early indication of certain types of cancer, according to a study by researchers. Hypercalcaemia is the most common metabolic disorder associated with cancer, occurring in 10 to 20 per cent of people with cancer. While its connection to cancer is well known, this study has, for the first time, shown that often it can predate the diagnosis of cancer in primary care." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 5- Calming down immune cells could hold key to melanoma treatment "Immune cells may be responsible for drug resistance in melanoma patients, according to research. Scientists found that chemical signals produced by a type of immune cell, called macrophages, also act as a survival signal for melanoma cells." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 6- Skirt size increase linked to 33 percent greater postmenopausal breast cancer risk "Going up a skirt size over a period of 10 years between your mid 20s and mid 50s is linked to a 33 percent greater risk of developing breast cancer after the menopause, finds a large observational study." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 7- How a single, genetic change causes retinal tumors in young children "Retinoblastoma is a childhood retinal tumor usually affecting children one to two years of age. Although rare, it is the most common malignant tumor of the eye in children. Left untreated, retinoblastoma can be fatal or result in blindness. It has also played a special role in understanding cancer, because retinoblastomas have been found to develop in response to the mutation of a single gene -- the RB1 gene -- demonstrating that some cells are only a step away from developing into a life-threatening malignancy." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
CANCER du SEIN : La taille de la jupe, un bon marqueur de risque
----------------------------------------"Le titre de l’étude « Association of skirt size and postmenopausal breast cancer risk in older women » qui porte donc sur une éventuelle association entre la taille du « bas » et le risque de cancer du sein peut sembler anecdotique. Cependant, les conclusions, publiées dans le très sérieux British Medical Journal (BMJ) rappellent en fait que l'obésité et en particulier l’obésité centrale, est un facteur de risque connu pour le cancer du sein." http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite BREAST CANCER : The size of the skirt, a good risk marker "The title of the "Association of skirt size and postmenopausal breast cancer risk in older women" therefore bringing about a possible association between the size of the "low" and the risk of breast cancer study may seem minor. However, the findings, published in the serious British Medical Journal (BMJ) recall that in obesity, particularly central obesity, is a known risk factor for breast cancer." http://bmjopen.bmj.com/content/4/9/e005400.ab...7a-4f05-b36b-8d04eeff98b5 French Article http://www.santelog.com/news/cancerologie/can...relasuite.htm#lirelasuite |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
1- Many Patients Excluded From Lung Cancer Clinical Trials Due to Prior Cancer, Study Finds
----------------------------------------"Lung cancer clinical trials exclude a substantial proportion of patients due to a history of prior cancer, research shows. "The resulting impact on study accrual is sobering," said one author who projected that the effects of these exclusions will only increase with time; there are currently more than 13 million cancer survivors in the U.S., which is a four-fold increase over the past 30 years." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 2- Strategy to reduce side effects in modern cancer therapy "A new strategy for reducing the often serious side effects of an important class of modern anticancer drugs -- tyrosine kinase inhibitors has been developed by an international team of researchers. The novel drug is supposed to restrict its activity with high selectivity to the malignant tumor." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 3- Discrepancies in access to new cancer drugs revealed "Access to potentially life-extending cancer drugs varies significantly in different regions of the world, two new studies show. Researchers say the results demonstrate the need for better collaboration between doctors and health authorities on an international scale, to ensure patients have access to the best treatments." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 4- More than 70% of young oncologists in Europe suffer symptoms of burnout "Across Europe, more than 70% of young cancer specialists are showing signs of burnout, the largest survey of its kind has revealed. The results have prompted calls for serious action to address the issue at all levels. Burnout could lead to serious personal consequences for the doctor such as anxiety, depression, alcohol or substance abuse and suicide, researchers warned." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 5- Protein 'map' could lead to potent new cancer drugs "Chemists have gained fresh insights into how a disease-causing enzyme makes changes to proteins and how it can be stopped. The scientists hope their findings will help them to design drugs that could target the enzyme, known as N-myristoyltransferase (NMT), and potentially lead to new treatments for cancer and inflammatory conditions." http://www.sciencedaily.com/releases/2014/09/...ily%3A+Top+Health+News%29 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
Cancer de la prostate : la calvitie synonyme de risque accru ?
----------------------------------------"Une étude suggère un lien entre l'apparition d'une calvitie et un risque accru de développer un cancer agressif de la prostate. Des résultats à interpréter avec prudence." http://www.sciencesetavenir.fr/sante/20140926...-risque-accru#xtor=EPR-6-[ActuSciences17h]-20140926 Prostate cancer : the increased risk of baldness synonymous ? "Study suggests link between the appearance of baldness and increased risk of developing aggressive prostate cancer. Results should be interpreted with caution." http://jco.ascopubs.org/content/early/2014/09/15/JCO.2014.55.4279 French Article http://www.sciencesetavenir.fr/sante/20140926...-risque-accru#xtor=EPR-6-[ActuSciences17h]-20140926 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
Les champignons, de nouveaux alliés contre le cancer
----------------------------------------"À l’origine de la pénicilline et de médicaments anti-rejets, les champignons se révèlent être aussi de précieux auxiliaires, notamment contre les tumeurs malignes." http://www.sciencesetavenir.fr/sante/20140925...tre-le-cancer#xtor=EPR-6-[ActuSciences17h]-20140926 |
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[CSF] Thomas Dupont
Veteran Cruncher Joined: Aug 25, 2013 Post Count: 685 Status: Offline |
Des chercheurs créent une protéine empêchant les métastases
----------------------------------------"Des chercheurs de l'université Stanford ont produit une protéine capable d’interrompre la voie de signalisation à l'origine des métastases. Cette stratégie semble efficace chez des souris atteintes de cancers du sein ou de l’ovaire." http://www.futura-sciences.com/magazines/sant...pechant-les-metastases%5D Researchers create a protein preventing metastasis "Researchers at Stanford University have produced a protein capable of disrupting signaling pathway causing metastasis. This strategy appears to be effective in mice with breast cancer or ovarian cancer." http://www.nature.com/nchembio/journal/vaop/ncurrent/full/nchembio.1636.html French Article http://www.futura-sciences.com/magazines/sant...pechant-les-metastases%5D |
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