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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/225139.php

"Article Date: 12 May 2011

'Octopus' Provides Cancer Breakthrough

A breakthrough in understanding a biological process that causes many common cancers including lung and breast cancer opens up a whole new realm of possibilities for the development of improved cancer drugs. The results are featured on the front cover of the journal Molecular and Cellular Biology published today. (12 May 2011).

Experts from STFC's Central Laser Facility (CLF) and Computational Science and Engineering Department (CSED) have solved a puzzle that has confounded scientists for more than 30 years..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/225164.php

"Article Date: 12 May 2011

Trigger For 'Undruggable' Lung Cancer Gene Offers New Treatment Hope

Cancer Research UK scientists have discovered that an enzyme called C-Raf controls a hugely important gene responsible for the development of lung cancer, according to research published in Cancer Discovery* yesterday (Wednesday).

The important gene - K-Ras - is one of the most commonly mutated genes in cancer. But it has been difficult to develop inhibitors of mutated K-Ras because of the structure of the molecule.

But now, a team based at Cancer Research UK's Cambridge Research Institute have shown that C-Raf is needed for mutated K-Ras to encourage the growth of lung cancer.

This opens up a completely new avenue of research looking at ways to block the growth of lung cancer, bypassing the K-Ras gene..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/225449.php

"Article Date: 16 May 2011

Prostate Cancer: To Treat, Not To Treat And When To Treat?

As physicians and researchers debate the merit of the prostate-specific antigen (PSA) test, questions have arisen about the test's ability to accurately identify the presence of prostate cancer, as well as how the test may be interpreted and better used to determine which prostate cancers require treatment and which do not. New research presented at the 2011 AUA Annual Meeting will bring light to the innovative possibilities for the use of PSA. A special panel, to be held on Monday, May 16, 2011 at 9:00 a.m., will discuss with members of the media the following studies:

How Soon Can We Identify Men at High Risk for Prostate Cancer Death? An Early Surveillance Strategy for Prostate Cancer (#986): A single blood test before the age of 50 could predict a man's long-term risk of prostate cancer death, according to research from Memorial Sloan-Kettering Cancer Center in New York and Lund University in Malmo, Sweden. Using data from the Preventive Project, a cardiovascular study enrolling men ages 33 to 50 between 1974 and 1986, and a combination of case-note review or death certificate data, researchers identified 141 men in the study who had subsequently died of prostate cancer. Nearly half (44 percent) of the deaths occurred in men whose PSA score fell in the top 10 percent (≥1.5 ng/ml). Researchers expanded their analysis to the top quartile of men, measuring free PSA and human glandular kallikrein 2 (hK2), and found that these markers helped to identify an additional 2.4 percent of deaths in the top 10 percent of risk. These data suggest that early analysis of PSA, free PSA and hK2 may provide critical insight into a man's risk of developing aggressive, life-threatening disease, enabling urologists to better assess when early intervention may be necessary..."
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Re: Interesting News Articles About Cancer

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Re: Interesting News Articles About Cancer

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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/225586.php

"Article Date: 17 May 2011

Liver Cancer Cells Coaxed To Commit Suicide By Common Anti-Inflammatory


The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.

Researchers also found that the combination of celecoxib with each of two chemotherapy drugs killed more liver cancer cells in culture, making those combinations more effective than either drug on its own.

"Each chemotherapy drug alone will reduce the growth of cancer cells, but when each single drug is combined with Celebrex, a greater growth suppression effect was observed," said Jiayuh Lin, senior author of the study and an associate professor of pediatrics at Ohio State University. "For clinicians, this research suggests the possibility of a new therapeutic strategy."

Celecoxib has this effect by acting on STAT3, a gene inside liver cancer cells that, when activated, allows those cancer cells to resist the effects of chemotherapy drugs. The researchers determined that the celecoxib molecule binds to STAT3 on so-called "hot spots," effectively blocking its ability to function..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/articles/225655.php

"Article Date: 18 May 2011

Regular Coffee Reduces Lethal Prostate Cancer Risk

A man who drinks either caffeinated or decaffeinated coffee regularly has a significantly lower chance of developing a more aggressive from of prostate cancer, researchers from the Harvard School of Public Health revealed in the Journal of the National Cancer Institute. This study follows another one last week that linked regular coffee drinking with a lower risk of a particular type of breast cancer.

The aggressive (lethal) cancer referred to here is the one that spreads to the bones.

Senior author, Lorelei Mucci wrote:

"Few studies have specifically studied the association of coffee intake and the risk of lethal prostate cancer, the form of the disease that is the most critical to prevent. Our study is the largest to date to examine whether coffee could lower the risk of lethal prostate cancer."

Prostate cancer is the most commonly diagnosed male cancer in the USA, and the country's second biggest cancer killer, after lung cancer. 16 million males worldwide are cancer survivors; 2 million are American.

Lead author, Kathryn Wilson said:

"At present we lack an understanding of risk factors that can be changed or controlled to lower the risk of lethal prostate cancer. If our findings are validated, coffee could represent one modifiable factor that may lower the risk of developing the most harmful form of prostate cancer."

Coffee contains several compounds which regulate insulin, reduce swelling (inflammation), and act as antioxidants - all considered beneficial regarding prostate cancer risk. Hence, the scientists chose to study it..."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/articles/226217.php

"Article Date: 24 May 2011

Colorectal Cancer Risk Higher If You Eat Red And Processed Meat, Lower If You Eat Fiber

Your risk of developing colorectal cancer is much higher if you consume red and processed meat regularly, while consumption of foods containing fiber helps protect you against the disease, researchers from Imperial College London revealed today. They say this is the most authoritative and comprehensive report on colorectal cancer risk to be published to date.

Elisa Bandera, MD, PhD, who served on the World Cancer Research Fund/American Institute for Cancer Research's Continuous Update Project (CUP) Expert Panel that authored the report, said:

"This report shows that colorectal cancer is one of the most preventable cancers. AICR has estimated that about 45 percent of colorectal cancer cases could be prevented if we all ate more fiber-rich plant foods and less meat, drank less alcohol, moved more and stayed lean. That's over 64,000 cases in the US every year."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/226302.php

"Article Date: 24 May 2011

California Companies Target Heart Disease, Cancer With More Than 240 Medicines In Development


At a time when cancer and heart disease are the nation's and the world's top killers, biopharmaceutical research companies headquartered in California are developing 243 of the 1,186 medicines in development for those dreaded diseases.

The California companies are developing 188 of 887 drugs for more than 20 types of cancer and 55 of 299 medicines for heart disease and stroke.

The cancer statistics are contained in a new report "Medicines in Development for Cancer" published by the Pharmaceutical Research and Manufacturers of America (PhRMA), while the data on heart disease and stroke are from a PhRMA report from early this year.

The cancer report and "Medicines in Development for Heart Disease and Stroke" can be found on the PhRMA website.

"California's companies are on the front line in both the ongoing War on Cancer and the intense fight against heart disease," said PhRMA spokesman Jeff Trewhitt. "The drugs they are testing could prove to be important to patients all over the world, including both the United States and California where heart disease and cancer are also the two leading causes of death."
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Michael2901
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Re: Interesting News Articles About Cancer

http://www.medicalnewstoday.com/releases/225752.php

"Article Date: 24 May 2011

Brisk Walking Could Improve Prostate Cancer Outcomes

Men with prostate cancer can improve their outcomes if they walk briskly for at least three hours a week following their diagnosis, according to a recent study in Cancer Research, a journal of the American Association for Cancer Research.

"It appears that men who walk briskly after their diagnosis may delay or even prevent progression of their disease," said lead researcher Erin Richman, Sc.D., a research associate at the University of California, San Francisco.

Richman said the evidence adds to the growing body of literature that suggests walking regularly may prevent a variety of adverse health problems, including cardiovascular disease and certain types of cancer.

"Walking is something everyone can and should do to improve their health," she said..."
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