Hi bringbackfreelove,
The most recent post we have was made on 28 April 2006 by Dr. Garrett M. Morris: http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=7042#56792


So here is how things are being done. Phase 1A ran 1,900 candidates against the Mutant HIV Protease Panel (270 varieties). This let us verify the program and found one interesting broad-spectrum candidate. (1 out of 1,900!) Phase 1B ran 230,000 candidates against 1 variety of Wild Type HIV Protease. Phase 2 is running 500,000 candidates against 1 variety of Wild Type HIV Protease. AND it is running the Top Hits from Phase 1B against the Mutant HIV Protease Panel (270 varieties). Presumably, Phase 3 will run the Top Hits selected from the 500,000 candidates of Phase 2 against the Mutant HIV Protease Panel (270 varieties). This is the real purpose of FightAIDS@Home. We are trying to discover drug candidates that are effective against a broad spectrum of mutated HIV varieties. So we are trying to run many candidates against the (standard) wild protease molecule, then select the best to run against a wide variety of mutated forms.

We could use 10 times as many contributing computers. We are not running short of candidates to test. Larry Fine estimates that we will not finish Phase 2 until August or September, yet that is just a start. What we are trying to do is produce a large number of drug candidates that show broad-spectrum potential. So far we have 1, found from 1,900 trials. Phase 2 will give us however many we find from 230,000 candidates (which ran through the initial selection step in Phase 1B). And Phase 3 will give us however many we find in 500,000 trials (being run right now through the initial selection process).

Lawrence

OK, OK

Thanks everybody...

Crunch, Crunch, Crunch...

I am running Boink (one WU for Each Core) AND WCG on Dual Core Athlon X2 3800... WOW.. Behold the awesome power of the AMD 64 X2...

I just shaved off a month till cure time by putting this box in production.

I don't even have hiv. I just like the idea of curing this scourge of a disease so we can "bring back free love". Yeah baby, yeah...

Are we only working on developing a new type of protease inhibitor? Why not try to develop a cure?

My AMD X2-4400 dual core liquid cooled computer has been kicking butt for about a year now with no problems at 100% CPU usage. The only minor inconvenience is that a little new coolant needs to be added every 3 months.

I'm looking forward to combining the quad core technology with Windows Vista 64-bit when programs become available to take advantage of the available power.

Guess, Sony, IBM and Toshiba are calling the multicore technology "cell processors".

http://www.pcstats.com/articleview.cfm?articleID=1727

Wasn't it in one of the Terminator movies that they said a 6 to 8 core processor is what made it possible to build a android machine?

I doubt it will produce that much power or capability but the future of distributed computing keeps looking a little better every year I been doing it.

My Day 1 observations

Yeah, it makes a huge difference using the boinc client on dual core. Actually I am running boinc (one wu for each core) AND WCG. So my cpu usage looks like:

25% WCG
25% Boinc 1
50% Boinc 2

The WUs take longer to complete, but I think overall throughput is a tiny bit higher.

1,900 Points in one day for a single box isn't too shabby... I may have to pick up a few more of these... My 2.4GHz P4 running WCG only pumps out about 800-950 points in one day (it is also a domain controller and a sql server, so I cant complain. It does its best)

I smell something burning...