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World Community Grid Forums
Category: Active Research
Forum: OpenPandemics - COVID-19 Project
Thread: Does Pfizer's vaccine and Merck's pill make OpenPandemics useless/too late? |
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Thread Status: Active Total posts in this thread: 16
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Dayle Diamond
Senior Cruncher Joined: Jan 31, 2013 Post Count: 450 Status: Offline Project Badges: 
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Vaccines are a race against time -- against variants.
----------------------------------------We absolutely need to develop cures for all the breakthrough infections. In the meantime, upgrade your mask and wear it reliably - N95 and K94 masks are broadly available. [Edit 1 times, last edit by Dayle Diamond at Nov 3, 2021 4:05:32 AM] |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges: 
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Also Merck appear to be price gouging. They're asking 43 times the estimated cost of production for a drug that was largely developed with public funds. It is not by accident that the U.S. leads the world in pharmaceuticals, especially the new ones for COVID. Companies can make a lot of money coming up with the first ones that work the best. The other countries just complain that they are not getting our supply. PS - As for the public funds, that was the deal they made with the government. If the government can do better, then they should do so. But if they squeeze the cost too far, the pandemic will be over before they get anything. PPS - It would make more economic sense for you to compare the price Merck is charging with the benefits of the medication, and also check to see how many people are willing to pay for it. I expect both will be large numbers. That is the way the market works, when it is allowed to do so. [Edit 4 times, last edit by Jim1348 at Nov 3, 2021 3:35:18 PM] |
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Sgt.Joe
Ace Cruncher USA Joined: Jul 4, 2006 Post Count: 7581 Status: Offline Project Badges: 
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The vaccine does not prevent you from becoming really sick. It reduces the chances of becoming really sick. One the parents of one of my daughter's coworkers both became sick with COVID-19. An the father died from COVID-19, even both were fully vaccinated. In most cases it does prevent you from becoming really sick. That is exactly what "reducing the chances of becoming really sick" means. It is not 100% effective, but it is more than 90% effective. Per the CDC: From cdc.gov Based on evidence from clinical trials in people 16 years and older, the Pfizer-BioNTech vaccine was 95% effective at preventing laboratory-confirmed infection with the virus that causes COVID-19 in people who received two doses and had no evidence of being previously infected. From cdc.gov Based on evidence from clinical trials, in people aged 18 years and older, the Moderna vaccine was 94.1% effective at preventing laboratory-confirmed COVID-19 infection in people who received two doses and had no evidence of being previously infected. Yes, there are some people who have been fully vaccinated and have become sick and/or died. The late General Colin Powell was one of these. He also had some co-morbidities which probably affected the effectiveness of the vaccine. From CNN: Powell had multiple myeloma, a cancer of plasma cells that suppresses the body's immune response, as well as Parkinson's, Peggy Cifrino, Powell's longtime chief of staff, confirmed to CNN. Even if fully vaccinated against Covid-19, those who are immunocompromised are at greater risk from the virus. The immunity from the vaccine wears off. These vaccines are new. We won't know for some time how long their immune effectiveness will last. This is also true of other vaccines. I remember getting polio shots and having to get boosters at later dates. I know I need to get a tetanus booster every so often (I think it is every seven years.) So it is not unusual to have the immunity from a vaccine wane over time. From a report on WJON radio in St. Cloud, Mn. on Aug 20, 2021: The Delta Variant COVID-19 surge is continuing to impact CentraCare and St. Cloud Hospital. CentraCare spokesman Dr. George Morris joined me on WJON. He says we are still seeing a surge with 37 people hospitalized with the Delta variant of COVID-19 with 12 of those in the ICU/Critical Care unit. Morris says they are seeing two-thirds of their hospitalizations in people under 50 years old and all 12 of those in the ICU/Critical Care unit are unvaccinated. Per the Minnesota Department of Health from May 2, 2021 to Sept. 26, 2021: The rate of death for those 50 to 64 fully vaccinated is 0.2 per 100,000. For those not fully vaccinated it is 1.8 per 100,000. The rate of death for those over 65 fully vaccinated is 1.6 per 100,000. For those not fully vaccinated it is 25.2 per 100,000. Sorry for the loss of one of your daughter's co-worker's parent.
Sgt. Joe
*Minnesota Crunchers* |
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Dayle Diamond
Senior Cruncher Joined: Jan 31, 2013 Post Count: 450 Status: Offline Project Badges:
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Moderna’s two-dose vaccine was 89% effective against the virus in March, but dropped to 58% in September
Pfizer’s vaccine went from 87% effective against the virus in March to 45% in September Johnson and Johnson’s single dose vaccine saw the biggest decline, falling from 86% effective to just 13% in the same timeframe. https://www.nature.com/articles/d41586-021-02532-4 |
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Sgt.Joe
Ace Cruncher USA Joined: Jul 4, 2006 Post Count: 7581 Status: Offline Project Badges:
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Moderna’s two-dose vaccine was 89% effective against the virus in March, but dropped to 58% in September Pfizer’s vaccine went from 87% effective against the virus in March to 45% in September Johnson and Johnson’s single dose vaccine saw the biggest decline, falling from 86% effective to just 13% in the same timeframe. https://www.nature.com/articles/d41586-021-02532-4 Hence the need for boosters. Cheers
Sgt. Joe
*Minnesota Crunchers* |
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