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Falconet
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November 2019 Paper - A diarylamine derived from anthranilic acid inhibits ZIKV replication

OpenZika paper that was referenced earlier in the December 2019 Project Update but not published here yet.
From the same project update:

"Our paper entitled “A diarylamine derived from anthranilic acid inhibits ZIKV replication” was accepted at the Scientific Reports journal. This study was a collaborative work with Prof. Ana Carolina Jardim, from the Federal University of Uberlandia, Brazil, and it reports a series of analogs from anthranilic acid screened by cell-based assays. Then, docking calculations performed in the OpenZika project suggested that NS3 helicase was the most probable target, which was experimentally validated by enzymatic assays."

Available here: https://www.nature.com/articles/s41598-019-54169-z
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[Edit 1 times, last edit by Falconet at Apr 7, 2020 7:31:14 PM]
[Mar 18, 2020 9:08:33 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Falconet
Master Cruncher
Portugal
Joined: Mar 9, 2009
Post Count: 3294
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Re: November 2019 Paper - A diarylamine derived from anthranilic acid inhibits ZIKV replication

Bumping this to bring more attention to other users and WCG.
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