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Category: Completed Research Forum: OpenZika Thread: November 2019 Paper - A diarylamine derived from anthranilic acid inhibits ZIKV replication |
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Falconet
Master Cruncher Portugal Joined: Mar 9, 2009 Post Count: 3294 Status: Offline Project Badges: |
OpenZika paper that was referenced earlier in the December 2019 Project Update but not published here yet.
----------------------------------------From the same project update: "Our paper entitled “A diarylamine derived from anthranilic acid inhibits ZIKV replication” was accepted at the Scientific Reports journal. This study was a collaborative work with Prof. Ana Carolina Jardim, from the Federal University of Uberlandia, Brazil, and it reports a series of analogs from anthranilic acid screened by cell-based assays. Then, docking calculations performed in the OpenZika project suggested that NS3 helicase was the most probable target, which was experimentally validated by enzymatic assays." Available here: https://www.nature.com/articles/s41598-019-54169-z AMD Ryzen 5 1600AF 6C/12T 3.2 GHz - 85W AMD Ryzen 5 2500U 4C/8T 2.0 GHz - 28W AMD Ryzen 7 7730U 8C/16T 3.0 GHz [Edit 1 times, last edit by Falconet at Apr 7, 2020 7:31:14 PM] |
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Falconet
Master Cruncher Portugal Joined: Mar 9, 2009 Post Count: 3294 Status: Offline Project Badges: |
Bumping this to bring more attention to other users and WCG.
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