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Falconet
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SN2S Update

Update:

After emailing the project scientist, Dr. Rosangela, mhammond got a response stating that the project was going well and that they were testing 16 drug candidates and that they were being tested at the Brazilian Biosciences National Laboratory in both in vitro and in vivo.

After that, I e-mailed Dr. Rosangela and she said that the SN2S project has been approved for clinical human trials (previously discussed here ) . The tests at the Brazilian Biosciences National Laboratory (the project team received the approval news just this week) are meant to assure a lower level of toxicity and side effects than Praziquantel (the only approved drug for the treatment of schistosomiasis, approved in the 70's). I assume this to be one of the main steps before moving on to the human trials.

Also I asked her the possibility of more work in the future. Dr. Rosangela said that the work we did in the 1st Phase of the SN2S project comprised over 5 Terabytes of potential targets and drugs and that they have another 6 Terabytes of potential targets and drugs to be tested in Phase 2. So, I think that the project will either resume at some point in the future or we will have a SN2S - Phase 2 project.

But don't take my word for it :D

Anyway, these are excellent news!
Exciting times for WCG these days!
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[Edit 4 times, last edit by Falconet at Apr 25, 2014 9:34:35 PM]
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gb009761
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Re: Any updates?

Bump - any news yet? biggrin
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Falconet
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Re: Any updates?

THK gave us a DSFL update so maybe she will give us an update for SN2S too.
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[Edit 1 times, last edit by Falconet at Mar 17, 2014 5:10:46 PM]
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Re: Any updates?

THK gave us a DSFL update so maybe she will give us an update for SN2S too.


Would be good if someone had some news.
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Falconet
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Re: Any updates?

Indeed it would.
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raybon
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Re: Any updates?

Yeah, I would love to see an update.
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Falconet
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Re: Any updates?

The website sadly isn't updated...

http://www.mestradoti.com.br/schistosoma/home
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mhammond
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Re: Any updates?

For what it's worth, I did send an email request for update via the 'contact us' link on the page that Falconet linked; if I get any reply I'll post it here.
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mhammond
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Re: Any updates?

Got the following via email:

Hi Mike,

Thank you for your help.
Project say no to schistosoma is very well.
We are texting 16 select drugs in vitro and in vivo in LNBio labs. http://lnbio.cnpem.br/
Our company ( Unica educacional ) win a project http://lnbio.cnpem.br/lnbio-and-renama-announce-selected-proposals/ . There was 220 project and our project is one of the select project. Only seven project are select.

I hope soon we have more informations.

Regards,

Rosangela Silqueira Hickson Rios
Cordinator of Masters on Information Technology applied to Computational Biology
www.mestradoti.com.br
rosangela@inforium.com.br


I did specifically ask if there would be any further work units but that inquiry was not addressed.

Regards,
Mike
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[Edit 1 times, last edit by mhammond at Apr 25, 2014 8:35:13 PM]
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Falconet
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Re: Any updates?

Wow that was fast :D

Thanks mhammond!
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