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World Community Grid Forums
Category: Completed Research
Forum: GO Fight Against Malaria
Thread: Interesting News Stories about Malaria, and the Fight Against It!! |
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Thread Status: Active Total posts in this thread: 74
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Anti-inflammatory drugs may improve survival from severe malaria
A novel anti-inflammatory drug could help to improve survival in the most severe cases of malaria by preventing the immune system from causing irrevocable brain and tissue damage. That's according to a study published May 24th in the journal Science Translational Medicine. Further details here: http://www.wehi.edu.au/site/latest_news/anti-...ival_from_severe_malaria/ |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
UCI researchers create mosquitoes incapable of transmitting malaria
American and French researchers have produced a model of the Anopheles stephensi mosquito — a major source of malaria in India and the Middle East — that impairs the development of the malaria parasite. These mosquitoes, in turn, cannot transmit the disease through their bites. Further details: http://today.uci.edu/news/2012/06/nr_malaria_120612.php |
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l_mckeon
Senior Cruncher Joined: Oct 20, 2007 Post Count: 439 Status: Offline Project Badges: 
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New target for malarial vaccine:
'Adults and children with malaria in Kenya who became immune to the parasite over time developed antibodies to a key malaria protein called PfEMP1, researchers from Melbourne's Burnet Institute discovered. The protein could be a key target for a future vaccine, said Professor James Beeson, the head of the institute's Centre for Immunology. Prof Beeson, a senior author of the study, said the protein could be targeted when the malaria parasite started to multiply in the blood stream. "This PfEMP1 protein appears to be the major target, or one of the most important targets, of the immune response at that time when the malaria parasite is replicating in the blood and causing illness," he told AAP. Prof Beeson said research was under way to work out how to develop a vaccine to induce an immune response and recreate that protective effect.' http://au.news.yahoo.com/a/-/mp/14433410/malaria-vaccine-research-breakthrough/ |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
University of Cape Town Researchers Believe They Have Found a Single Dose Cure for Malaria
National Geographic reports: "The University of Cape Town’s Science Department believes that it has found a single dose cure for Malaria." Its researchers have been working on this compound, from the aminopyridine class, for several years. Unlike conventional multidrug malaria treatments that the malaria parasite has become resistant to, the researchers believe that they have discovered a drug that over 18 months of trials ”killed these resistant parasites instantly”. Details at: http://newswatch.nationalgeographic.com/2012/...le-dose-cure-for-malaria/ |
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Papa3
Senior Cruncher Joined: Apr 23, 2006 Post Count: 360 Status: Offline Project Badges: 
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More details here on the new University of Cape Town drug...
http://www.dailymail.co.uk/health/article-219...cure-strains-malaria.html Scientists believe they are close to creating a single-dose cure for all strains of malaria. A team from the University of Cape Town said a recently discovered compound, called MMV390048, may also be able to block transmission of the parasite from person to person [...] the UCT team led by Professor Kelly Chibale said their new treatment 'killed these resistant parasites instantly' in more than 18 months worth of trials. [...] The promising new compound shows potent activity against multiple points in the malaria parasite's lifecycle, which is why it could stop the parasite from spreading between human populations. [...] The compound is being developed by scientists at the University of Cape Town in collaboration with the Medicines for Malaria Venture based in Switzerland. So far it has displayed a complete cure of animals infected with malaria parasites in a single dose given orally, and thus has the potential to cure millions of people. It is also active against a wide panel of resistant strains. [...] |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges: 
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Here is an interesting story on the resistance of malaria to chloroquine, and the difficulty of developing new drug candidates.
http://mag.uchicago.edu/science-medicine/exposure-0?msource=MAG10 |
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cjslman
Master Cruncher Mexico Joined: Nov 23, 2004 Post Count: 2082 Status: Offline Project Badges: 
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Here's an interesting story about Malaria, although it's more based on how cell phone technology is being used to fight a drug resistant strain in Cambodia.
----------------------------------------Fighting malaria in Cambodia with Google Earth and SMS CJSL Crunching for a better tomorrow... |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Possible new species of mosquitoe in Africa appears to adjust time of activity to avoid being stopped from biting humans by bed nets.
New Scientist report: http://www.newscientist.com/article/dn22306-m...rss&nsref=online-news |
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branjo
Master Cruncher Slovakia Joined: Jun 29, 2012 Post Count: 1892 Status: Offline Project Badges: 
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(Reuters) - The world's first potential malaria vaccine proved only 30 percent effective in African babies in a crucial trial, calling into question whether it can be a useful weapon in the fight against the deadly disease. http://www.reuters.com/article/2012/11/09/us-...gsk-idUSBRE8A80I120121109 Just keep crunching my friends-in-arms. We need more shrubberies  Cheers and NI!  Crunching@Home since January 13 2000. Shrubbing@Home since January 5 2006  [Edit 2 times, last edit by branjo at Nov 10, 2012 10:19:54 PM] |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges:
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This reports on efforts to stop drug-resistant strains from spreading from South East Asia to Africa.
----------------------------------------http://www.bbc.co.uk/news/world-asia-20178399 [Edit 1 times, last edit by Jim1348 at Nov 23, 2012 10:03:12 PM] |
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