The first phase of the project will computationally evaluate the potential potency of millions of compounds using the new software AutoDock Vina. The second phase of the project will computationally re-evaluate the potency of the same compounds using the program AutoDock4.2. These two different types of docking programs each use different algorithms when searching for the location where a compound binds and when predicting the detailed mode it uses to bind to that location of the protein target, and they both use different "scoring functions" to evaluate the potency of the binding mode they predicted. Since no computational tools are perfectly accurate, harvesting compounds that score well with multiple different types of computational tools can increase the probability of discovering promising new compounds.