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World Community Grid Forums
Category: Completed Research
Forum: Drug Search for Leishmaniasis Forum
Thread: A novel oral treatment for leishmaniasis has potential to save thousands of lives |
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Thread Status: Active Total posts in this thread: 7
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
The website MedicalXpress reports:
"A tropically stable liquid therapy for leishmaniasis, a disease known as the Baghdad boil, shows a significant decrease in infection after less than a week of treatment. This research is being presented at the 2011 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in Washington, D.C., Oct. 23 – 27." Full details at: http://medicalxpress.com/news/2011-10-oral-tr...-potential-thousands.html |
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johncmacalister2010@gmail.com
Veteran Cruncher Canada Joined: Nov 16, 2010 Post Count: 799 Status: Offline Project Badges: 
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The website MedicalXpress reports: "A tropically stable liquid therapy for leishmaniasis, a disease known as the Baghdad boil, shows a significant decrease in infection after less than a week of treatment. This research is being presented at the 2011 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in Washington, D.C., Oct. 23 – 27." Full details at: http://medicalxpress.com/news/2011-10-oral-tr...-potential-thousands.html Interesting. I wonder how long it will take for this to become widely available? Thanks for the post.   crunching, crunching, crunching. AMD Ryzen 5 2600 6-core Processor with Windows 11 64 Pro. AMD Ryzen 7 3700X 8-Core Processor with Windows 11 64 Pro (part time) |
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Somervillejudson@netscape.net
Veteran Cruncher USA Joined: May 16, 2008 Post Count: 1065 Status: Offline Project Badges: 
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Fascinating as with such an apparent quick and effective response I wonder if it will replace the current treatment that article describes which consists of one month of IV treatment! Thanks forth post CaptainMidnight.
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
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Falconet
Master Cruncher Portugal Joined: Mar 9, 2009 Post Count: 3315 Status: Offline Project Badges: 
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Great news indeed.
----------------------------------------96% reduction in infection rates is awesome. Maybe the DSFL scientists should analyze this study to see if new directions in the research must be followed?  - AMD Ryzen 5 1600AF 6C/12T 3.2 GHz - 85W - AMD Ryzen 5 2500U 4C/8T 2.0 GHz - 28W - AMD Ryzen 7 7730U 8C/16T 3.0 GHz |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Well this actually has more to do with treating certain fungal infections in immune comprised individuals then treating leishamaniasis. The drug mentioned is usually only used as a last resort for a certain type of leishamaniasis. Not exactly sure how a anti-fungal drug battles a parasitical infection but it maybe it's just an unexpected side benefit of the drug.
http://www.publicaffairs.ubc.ca/ubcreports/2009/09jun04/diseases.html details it. There have been years of testing the method and it looks like it validates the prior testing of the delivery method so the new method could be standard in a few years. I know it's slow but fast tracking a new method of delivering a drug could have bad consequences if not tested thoroughly. This is a better delivery method of the drug that could be applied to other drugs that currently are applied by IV. This would make getting the drugs out to people that need it not require a lengthy hospital stay which in the third world is a prohibitive expense and often extremely difficult in remote areas. Not to mention the first world would also benefit. So three cheers to the doctors and scientists who helped make this breakthrough. |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
One widely used anti-malarial cocktail includes an anti-fungal drug. A fungus (eukaryote) responds to different types of drugs than a bacterial (prokaryote) disease would. Sometimes while treating a fungus doctors see that it also affects other eukaryote diseases.
Lawrence |
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