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uplinger
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Experiment 33 Starting soon

Greetings,

We will be starting experiment 33 soon. These batches start with 13985. At the request from the researchers we will be running these before finishing experiment 32. So you will see a jump from batch 12900 to 13984.

Thanks,
-Uplinger
[May 18, 2010 7:54:15 PM]   Link   Report threatening or abusive post: please login first  Go to top 
rilian
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Re: Experiment 33 Starting soon

good news!

just for easier access, here is status page http://fightaidsathome.scripps.edu/status

Experiment 32: 27% Completed
Experiment 33: 0% Completed
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[May 18, 2010 9:14:01 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Sekerob
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Re: Experiment 33 Starting soon

Not sure how to read this... will the remainder of exp.32 be postponed till exp.33 is done in whole?

As for exp.32, 12900 suggest a completion in the range of 53-54% taking the batch range faah11647 - faah13,984.
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[May 18, 2010 9:26:38 PM]   Link   Report threatening or abusive post: please login first  Go to top 
gb009761
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Re: Experiment 33 Starting soon

Uplinger, have the researchers anything they're able to share as to the reason behind this request - perhaps a promising lead? biggrin
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[May 18, 2010 9:39:17 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Randzo
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Re: Experiment 33 Starting soon

I think that they know that integrase is most important for HIV replication. So it is very promising target for potential inhibitors. So they wouldn`l like to wait more.
[May 18, 2010 10:28:02 PM]   Link   Report threatening or abusive post: please login first  Go to top 
mgl_ALPerryman
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biggrin Re: Experiment 33 Starting soon

Hi Sekerob,

Yes, the rest of Experiment 32 will be postponed until Exp. 33 has finished. Since input files don't really have a shelf-life, we'll just resume Exp. 32 later. Since all the work units are conveniently numbered, this type of thing is easy to implement and keep track of.

We want to bump Exp. 33 to a higher priority in the FAAH queue, because we have not yet performed any virtual screens against our new models of HIV integrase. We have many new results against HIV protease that need to be evaluated in test tubes (which I'll discuss in the next volume of the FAAH Newsletter in June), and we have several more virtual screens against HIV protease that still need to be analyzed. Thus, while we're analyzing and testing the previous screens against HIV protease, we're going to start extending the scope of these FAAH experiments by performing this new type of screen against HIV integrase in Exp. 33. Performing these screens against HIV integrase is a huge milestone for FightAIDS@Home. We want to start searching for these potential new classes of integrase inhibitors as soon as possible.

Thank you all very much for your help,
Alex Perryman, Ph.D.
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Dataman
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Re: Experiment 33 Starting soon

Thank you for the explaination. peace

cowboy
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[May 19, 2010 7:42:55 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Randzo
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Re: Experiment 33 Starting soon

Thanks for update Mr. Perryman.
I wish every project would have such a good communication with chrunchers like FAAH. Hope this experiment will be desired milestone for fight with HIV virus.
I am sure one day flag of faah will be on defeated HIV.
[May 19, 2010 10:15:56 PM]   Link   Report threatening or abusive post: please login first  Go to top 
nasher
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Re: Experiment 33 Starting soon

yes thank you for the update... it is always nice to know whats coming up and it is nice to see the progress.

good luck all and happy crunching
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[May 20, 2010 12:37:42 AM]   Link   Report threatening or abusive post: please login first  Go to top 
AnRM
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Re: Experiment 33 Starting soon

Sounds very promising....thanks for the update.....smile
[May 21, 2010 12:05:35 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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