| Index | Recent Threads | Unanswered Threads | Who's Active | Guidelines | Search |
 |
World Community Grid Forums
Category: Community
Forum: Chat Room
Thread: Muscle preservation even with no spinal connection |
| No member browsing this thread |
|
Thread Status: Active Total posts in this thread: 5
|
|
| Author |
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
'First, they genetically removed NF-kB from the leg muscles of mice by blocking IKK2, a protein needed to activate the signal. Then, to mimic spinal injury, they blocked the communication between the spinal cord and the lower leg muscle – an intervention that under normal circumstances inevitably leads to muscle wasting.
"What we observed was truly amazing", says Rosenthal, Head of EMBL's Mouse Biology Unit. "The mice showed hardly any muscle wasting after the injury; their muscle fibres maintained almost the same size, strength and distribution as in a healthy muscle. But that's not all; blocking IKK2 also helped muscle healing. Without the NF-kB signal the muscle regenerated much better and faster." Protection against muscle atrophy was even stronger when a gene encoding growth factor IGF-1 was added to muscle tissue lacking NF-kB.' http://www.embl.org/aboutus/news/press/2006/02nov06/index.html |
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
'First, they genetically removed NF-kB from the leg muscles of mice by blocking IKK2, a protein needed to activate the signal. Then, to mimic spinal injury, they blocked the communication between the spinal cord and the lower leg muscle – an intervention that under normal circumstances inevitably leads to muscle wasting. "What we observed was truly amazing", says Rosenthal, Head of EMBL's Mouse Biology Unit. "The mice showed hardly any muscle wasting after the injury; their muscle fibres maintained almost the same size, strength and distribution as in a healthy muscle. But that's not all; blocking IKK2 also helped muscle healing. Without the NF-kB signal the muscle regenerated much better and faster." Protection against muscle atrophy was even stronger when a gene encoding growth factor IGF-1 was added to muscle tissue lacking NF-kB.' http://www.embl.org/aboutus/news/press/2006/02nov06/index.html Aww big deal  I been preserving ok with no spinal communications for years!   *hic* Jus give'em a Pint-O- Ale!  , or two! , ooor three! , maybe even four  , but not five   Oneguy |
||
|
|
Sekerob
Ace Cruncher Joined: Jul 24, 2005 Post Count: 20043 Status: Offline |
Oneguy, is that from the waist up or the waste down (ROFLMAO)
----------------------------------------Seriously, the discoveries are amazing.... read how filling the gap in a spinal cord break with a special nutrient gel would cause the nerv fibers to grow again..... no this was not a review of a movie with Gene Hackman. cheers
WCG
Please help to make the Forums an enjoyable experience for All! |
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Oneguy, is that from the waist up or the waste down (ROFLMAO) Seriously, the discoveries are amazing.... read how filling the gap in a spinal cord break with a special nutrient gel would cause the nerv fibers to grow again..... no this was not a review of a movie with Gene Hackman. cheers Of course; the waist up! (The down side simply gave up and atrophied.)  Good article; I wonder if it could used for extended bouts of zero gravity.  I seem to have missed the Healing Gel part but two of the Authors of the Study are real Hotties!  Foteini Mourkioti and Nadia Rosenthal  I wonder what P. Kratsios, and M. Pasparakis look like!  Eat your heart out Gene Hackman!  Hubba Hubba!  |
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
obviously 'Tops in their Field'
 None of the male scientists can keep their minds on the work long enough to get anything done...  Cheer. ozylynx |
||
|
|
|