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Thread: Protein folding in hundreds instead of trillions of steps? |
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Thread Status: Active Total posts in this thread: 4
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Bon Kuhlman
Cruncher Joined: Apr 2, 2006 Post Count: 10 Status: Offline Project Badges: 
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A French and Italian team has recently devised a way to streamline protein folding, reducing the number of required steps from trillions to hundreds.
Fast folding! If this were applied to either Folding@home or WCG we could dramatically reduce the time to complete projects like the Human Proteome Folding project. |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
I expect that Folding@Home is looking hard at this research. It is right up their alley.
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we45dfa35gh3476
Advanced Cruncher Joined: Apr 19, 2006 Post Count: 57 Status: Offline |
Discussion of this @ Dr. Baker's group:
----------------------------------------http://boinc.bakerlab.org/rosetta/forum_thread.php?id=2324 Dr. Baker: It certainly is an interesting claim, but I haven't yet seen the paper so cannot really assess it. Other: It seems they are describing the actual folding process and how it happens according to the rules of physics. That is more what folding@home is doing - simulating the whole folding process of a protein... the paper Hoelderl1n linked to they studied one tiny protein, with just 36 amino acids. Whether there findings work for other proteins is not clear. [Edit 1 times, last edit by we45dfa35gh3476 at Sep 24, 2006 2:22:09 AM] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Hello we45dfa35gh3476,
In your 2nd quote you omitted the information that the paper was NOT studying an all-atom model of the 36-amino acid protein. Which is a very important limitation. Lawrence |
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