Feb 1, 2007. Using the library of expression signatures generated through the "Help Defeat Cancer" project, the research team at The Cancer Institute of New Jersey has begun to develop and evaluate a prototype system for performing data-mining and staging disease progression.

Feb 27, 2007. Certain proteins must be localized to specific sub-cellular compartments in order to be considered clinically relevant. Using the pattern recognition algorithms that our team is developing as part of our NIH-funded project (5R01EB003587-02), a computer-based prototype is being evaluated for its capacity to automatically characterize nuclear, cytoplasmic, and membrane localization of protein expression. As part of the "Help Defeat Cancer" project this approach has already been shown to provide reliable, objective analysis when used to evaluate imaged tissues from a 186 breast cancer patients and additional studies are underway.