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research project against SARS will/can appear?

Hello all,
When I was searching for information around distributed computing, I found the project named "D2OL (Drug Design Optimization Lab)" working on other deseases which (I think) haven't appeared on this grid. One of them which I saw as interesting was SARS (Severe Acute Respiratory Syndrome). As many of you know, not only Asia but many nations out of the region witnessed the great spread of the desease. For example, Canada had 250 patients and 38 deceased, USA had 71 patinets, Germany had 10 patients, France had 7 patients and 1 deceased and so on. It's not only the threat of Asians. It's yours, too. However, the background of the viruses which can cause SARS is unclear yet, therefore the cure of SARS is also uncertain. To prevent ourselves from being seized with the desease, we can start researching on SARS viruses and cures. Of course there are other diseases which can be started, but from the following points probably SARS is one of the best targets if another project will be added to the grid.
    1) Many computers from Asian join distributed computing
    2) other projects aren't working on the disease particularly
*1) According to statistics for BOINC projects, Asian countries (nations) such as Japan, China, Hong kong and Taiwan are among the top 50. Because China is a developing country, it has capability for participate more than today.
*2) There are projects which study on human proteins to find a solution with human diseases, but AFAIK there are no major projects which study particularly on SARS except D2OL.

You can expect many Asian users would participate in the project... I cannot imagine what have to be studied around SARS viruses, but I would crunch at least. Are there any proposals which have been submitted of projects against SARS viruses and cures?
Thanks for reading,
suguruhirahara
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[Edit 1 times, last edit by Former Member at Aug 14, 2006 6:15:55 PM]
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Re: research project against SARS will/can appear?

Hello suguruhirahara,
As far as I know, we are not currently evaluating any projects about SARS. We are receiving project proposals from countries outside the USA now, but I have not heard of any from the Far East. We are trying to set up our website to use Chinese and Japanese, which may result in some project proposals.

Here is a list of current active distributed computer projects: http://distributedcomputing.info/projects.html

The list of future projects is probably incomplete, since it does not list any in the Life Sciences: http://distributedcomputing.info/upcoming.html

Lawrence
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Re: research project against SARS will/can appear?

Being in Singapore myself, one of the countries hit hard by SARS in the previous years - and now the bird flu threat looming, I am in opinion that it is about time we had a grid computing project benefiting respiratory-based diseases - specifically flu.

The last influenza pandemic claimed an estimated 1 million lives over afew months in a single city alone, and now with greater accessibility around the globe, coupled with huge population concentrations at cities, the next pandemic is poised to kill perhaps even tens of millions unless we do something about it.

If WCG ever receives a proposal for - and I think it should actively encourage the formation of - a groundbreaking project researching into influenza, particularly bird flu, I will heartily support it. SARS has passed, and now Avian Influenza is just over the horizon, pending human-to-human transmission, no matter what steps we take.

The research carried out into it may be too late to translate into lives saved if it remains purely in the domain of medical computer clusters and pharmaceutical companies that say "We're already at the limit of our research capacity".

I am very certain that computing projects targeted at influenza exist, but they are just in private institutes or in places not informed enough of grid computing - scientists who want to do something about it but do not have the processor power.

Grid computing should be rushed to a whole new level of publicity, especially in the East, and should actively search for such time-critical research partners so that we can make an impact before the disease finally evolves into its most virulent form and hits a home near yours.

I'm not saying that the WCG isn't doing enough, or hasn't got the right partners, or isn't continually expanding and developing. Because it is, and it is making a difference, yea.

But what I am opinionating is that we actively focus our efforts at countering in time the greatest medical threat - not ongoing disease - that the 21st century has known, before it claims its' first million.

And perhaps IBM, a multinational corporation with offices in every corner of the globe, specifically in modernised parts of Asia, should be the principal agent of act on this frontier, and FAST.
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[Edit 1 times, last edit by Former Member at Aug 15, 2006 4:49:27 AM]
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Re: research project against SARS will/can appear?

If WCG ever receives a proposal for - and I think it should actively encourage the formation of - a groundbreaking project researching into influenza, particularly bird flu, I will heartily support it. SARS has passed, and now Avian Influenza is just over the horizon, pending human-to-human transmission, no matter what steps we take.

yes, Avian Flu is also the the threat in Asia, espeliclly East Asia. Anyone knows which DC projects are studying on the disease?
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[Edit 1 times, last edit by Former Member at Aug 15, 2006 5:38:31 AM]
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Re: research project against SARS will/can appear?

I frankly don't think there are public DC projects running research into SARS or the H5N1 Flu virus currently. Most research into flu is carried out in the East, because that's where the threat is greatest.

It is not only a threat in East Asia, it is:
1) The most critical potential virus threat in East Asia - Deaths have occured.
2) A severe threat to Europe - Infections have occured.
3) A threat to America.

I has the potential to kill more people than a thousand 9/11 attacks combined.
Yet few people pay attention to it.
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Re: research project against SARS will/can appear?

I has the potential to kill more people than a thousand 9/11 attacks combined.
Yet few people pay attention to it.

I'm agree with this point, but I doubt whether people pay attention to the disease badly.
    1. The diseases which have appeared (say AIDS/Cancer)
    2. Those which potentially appear (say Bird flu)
Obviously they tend to pay more attention to the former diseases. I think both should be concerned with at the same level.
We are trying to set up our website to use Chinese and Japanese, which may result in some project proposals.

Please let me know if I can do something for it eg translation into Japanese...

Thanks for reading,
suguruhirahara
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[Edit 1 times, last edit by Former Member at Aug 15, 2006 3:35:32 PM]
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Re: research project against SARS will/can appear?

We doesn't have to study on the bird flu vaccine anymore, maybe...
Glaxo has bird flu 'breakthrough'
UK drugs firm GlaxoSmithKline believes it has developed a vaccine for the H5N1 deadly strain of bird flu that may be capable of being mass produced by 2007.

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Re: research project against SARS will/can appear?

But how do you test it?
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Re: research project against SARS will/can appear?

But how do you test it?

hmm... I'm not sure thinking
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Re: research project against SARS will/can appear?

The news report says they conducted clinical trials in Belgium. The article isn't specific but I gather the test in Belgium proved humans produce the correct antibodies after innoculation with the vaccine and side effects are minimal.

I suppose the next level of testing will occur after they find a way to produce the vaccine in large volumes. I imagine they would innoculate larger populations as well as smaller populations that are at high risk of infection. They'll watch for side effects and track infection rates to see how effective the vaccine is.
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