Hi everyone,

While I am not an expert, I understand that protease inhibitors are being used less and less in favor of other drugs which work better and have less side effects, lilke reverse transcriptase inhibitors and, more recently, fusion inibitors (integrase inhibitors, if I remember correctly).

Also, common sense seems to suggest that stopping the virus from entering the T-cell could be more effective than trying to stop replication once it is in.

If that is the case, why are we still dedicating our efforts to protease?

Can anyone enlighten me?

A big thank you to everyone involved in this project, I love being able to contribute.


ciao,
Fabio