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Category: Completed Research Forum: OpenZika Thread: Zika Virus- Mutation and the challenges - please read |
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QuantumEthos
Senior Cruncher Joined: Jul 2, 2011 Post Count: 336 Status: Offline Project Badges: |
Zika Virus- Mutation and the challenges
i have thought matrixed the idea behind the zika viri research and i come to a disturbing conclusion about the problematic relationship between the zika virus and a comparable example the common flue .. and swine flue... both forms can prove deadly and problematic for chemical treatments ... you see the flue mutates between hosts and within a single host quite regularly... "So what is the problem zika is not the same !" the problem is that zika like the flue or the cold is an example of cross species parasitical entities ... Therefore changes between host and delivery host (the mosquito); Both have changing dna though breeding cycles and consequentially the zika virus must mutate rapidly to out perform host adaptation.. chemicals that bind now most probably will not perform their job's at a later mutation cycle and may vary in performance over the mutation bias... Rupert S the very nature of rapidly developing mutation both changes and challenges the non adaptive chemical treatment bias of research and scientific study ! One sample of the genetic code may not always prove valid for all variants and most problematically not prove effective, This variance is after all what provides for survivors of diseases like the plague and the forming of man from the suggested primate ancestry. so what could we do about this ? have the bind points proved to be unchanging or mutating .. are their variances in these bind points ? what are the inevitable problems we will face in science and medicine of these crucial issues. Rupert S http://bit.ly/ViralMutation |
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QuantumEthos
Senior Cruncher Joined: Jul 2, 2011 Post Count: 336 Status: Offline Project Badges: |
further references in the conclusion of the text Rupert S
zika virus further research - http://esa-space.blogspot.com/2016/02/zika-virus-further-research.html zika virus - http://esa-space.blogspot.com/2016/02/zika-virus.html most relevant - Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004044 mutation rates amongst RNA Viri http://www.pnas.org/content/96/24/13910.long viral mutation rates and math http://jvi.asm.org/content/84/19/9733.full The prediction of virus mutation using neural networks and rough set techniques https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867776/ Predicting virus mutations through statistical relational learning https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-15-309 Replication and Adaptive Mutations of Low Pathogenic Avian Influenza Viruses in Tracheal Organ Cultures of Different Avian Species http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042260 |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges: |
so what could we do about this ? have the bind points proved to be unchanging or mutating .. are their variances in these bind points ? The problem would seem to be pervasive in this type of work. Do you conclude that the researchers have not considered it already? Have they not looked at the "bind points" (whatever they are)? |
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Sgt.Joe
Ace Cruncher USA Joined: Jul 4, 2006 Post Count: 7574 Status: Offline Project Badges: |
QuantumEthos,
----------------------------------------I know you are trying to help, but you should direct your observations to the scientists who can do something about it rather than the crunchers. Cheers
Sgt. Joe
*Minnesota Crunchers* |
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QuantumEthos
Senior Cruncher Joined: Jul 2, 2011 Post Count: 336 Status: Offline Project Badges: |
the relevance is we need to vaccinate! - research Vaccines.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867776/ - code relevance. https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-15-309 http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004044 http://www.pnas.org/content/96/24/13910.long http://jvi.asm.org/content/84/19/9733.full http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042260 |
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