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Sekerob
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Interesting Medical News (Non-WCG Related Projects)

Add your medical news here which presently seems to be all over the place. For the moment do not include AIDS, Cancer, Dengue related diseases, Genome and Proteome Folding as they have or will have their specific Project Forum.

First up:
Bone Hormone Linked to Obesity and Diabetes

"New research has shown that the skeletal system may be an important player in preventing obesity and type-2 diabetes in animals. This may also be true for humans, and thus represents an important development for the treatment of these health conditions. From the article: 'Not only do bones produce a protein hormone, osteocalcin (pictured), that regulates bone formation, but this hormone also protects against obesity and glucose intolerance by increasing proliferation of pancreatic beta cells and their subsequent secretion of insulin. Osteocalcin was also found to increase the body's sensitivity to insulin and as well as reducing its fat stores ... "The skeleton used to be thought of as just a structural support system. This opens the door to a new way of seeing the bones," said Dr. Gerard Karsenty, chairman of the department of genetics and development at Columbia University Medical Center in NYC, who headed the team that made the discovery.'"

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Former Member
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Re: Interesting Medical News (Non-WCG Related Projects)

Using Bacteriophages to Combat Bacterial Infections:
http://news.bbc.co.uk/2/hi/health/6943779.stm
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bjbdbest
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Re: Interesting Medical News (Non-WCG Related Projects)

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twilyth
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Re: Interesting Medical News (Non-WCG Related Projects)

Artificial transcription activators (molecules that target a gene and promote it's expression) have been tested in live cells. Since artificial activators are small molecules that can more easily pass through cell membranes, it should be possible to tie them to another molecule that will target genes that are silenced in some diseases such as cancer.

See Artificial Activators
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twilyth
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Re: Interesting Medical News (Non-WCG Related Projects)

Possible vaccine for Alzheimer's.

One protein involved in Alzheimer's is an improperly folded version of a protein called Tau. A new vaccine appears to reduce the accumulation of this protein in mice engineered to develop excess abnormal Tau. This resulted in less abnormal Tau and significantly improved motor function. The role of the other protein involved in Alzheimer's, amyloid beta, and how it interacts with Tau isn't clear.

See Possible Alzheimer's vaccine
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twilyth
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Re: Interesting Medical News (Non-WCG Related Projects)

So-called junk DNA - and its products, micro RNA's - may be crucial in the effective expression of a key cancer suppressor gene. Micro RNA's regulate messenger RNA (mRNA) which is used to transmit instructions for building proteins.

It turns out that when the expression of 2 of 3 micro RNA's linked to the P53 tumor suppressor gene is restored in a common type of lung cancer, that the extent of aberrant growth is reduced.

See Micro RNA and cancer
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twilyth
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Re: Interesting Medical News (Non-WCG Related Projects)

Compounds in cranberry juice increase sensitivity of ovarian cancer cells to platinum based chemotherapy drugs 6 fold.

The dose tested - in vitro - was equivalent to consuming one cup of cranberry juice. It is believed that a class of proanthocyanidines (type A) - a type of antioxidant - unique to cranberries is responsible for blocking the effect of tumor promoter proteins.

See Cranberry Juice Improves Chemotherapy
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Re: Interesting Medical News (Non-WCG Related Projects)

A New "Designer" Treatment for Multiple Sclerosis:
http://www.sciam.com/article.cfm?articleID=AF...51357EB1&chanID=sa003

Research shows that estrogen can be used to counteract nerve cell degeneration caused by MS without increased risks of breast and uterine cancers

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Re: Interesting Medical News (Non-WCG Related Projects)

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