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Former Member
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HOW FAR ARE WE?

HEY GUYS AND CRUNCHERS

WHAT DO YOU THINK?
IS POSSIBLE A CURE FOR AIDS DESEASE?
HOW FAR ARE WE?
WHY THE PEOPLE DONT BELIEVE THAT THIS PROJECT (FOR EG.) ARE SEARCHING BETTER THERAPIES?
WHAT THE PERSPECTIVES?

KEEP IN TOUCH
[Dec 19, 2006 6:50:08 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Brecht Crombez
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Re: HOW FAR ARE WE?

check this website:http://fightaidsathome.scripps.edu/

it's updated sometimes (the text on the bottom of the site about 'last update' is incorrect!)

greets
[Dec 19, 2006 7:15:23 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Former Member
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Re: HOW FAR ARE WE?

Please don't use CAPS LOCK when you post.
It's annoys people. (Me)

YES Aids will be curable when we know enough about it.

We have started to check our toolbox for compunds to use againt Aids.
This is a rather large toolbox and it will take awhile.
THEN we can start to talk about curing.

Why don't the people belive in God? devilish
[Dec 19, 2006 8:06:11 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Former Member
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Re: HOW FAR ARE WE?

In a nutshell, it's an extraordinarily difficult virus to match a cure to at any single instant, let alone to cure it for life because its random mutations are complex, rapid, and forever evading.
[Dec 25, 2006 6:39:47 AM]   Link   Report threatening or abusive post: please login first  Go to top 
Former Member
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Re: HOW FAR ARE WE?

AIDSmap is a good site to follow news items relating to AIDS: http://www.aidsmap.com/en/default.asp
[Dec 25, 2006 9:54:22 AM]   Link   Report threatening or abusive post: please login first  Go to top 
steffen_moeller
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Re: HOW FAR ARE WE?

Nice site, but incomplete. I just aidsmap to place a link to FAAH on their site.
[Dec 25, 2006 3:18:31 PM]   Link   Report threatening or abusive post: please login first  Go to top 
Former Member
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Re: HOW FAR ARE WE?

Just to clarify, it seems to me that the FightAIDS@Home project is not actually looking for a CURE for AIDS. A cure would mean an anti-HIV vaccination that someone could get to prevent the spread of AIDS even before HIV is acquired. Rather the FightAIDS@Home project is searching for antiviral drugs. These drugs are for combating the virus after someone is already infected. They can't actually cure AIDS, but could help someone to live much longer. Am I right on this?
[Jan 2, 2007 12:42:32 AM]   Link   Report threatening or abusive post: please login first  Go to top 
Gollumer
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Re: HOW FAR ARE WE?

From what I read, I doubt we can ever "cure" a retrovirus. effective innoculation against such a rapidly mutating virus is also almost impossible.

From the NIH:
"HIV continually evolves because of genetic mutation and recombination. Thus, researchers will need to account for strain variation within individuals and among populations when developing HIV vaccines. Initially, a person is infected with only one or a limited number of HIV variants. Once HIV infection becomes established, however, the virus continually undergoes genetic changes, and many variants may arise within an infected person.

Whenever a drug or immune response destroys one variant, a distinct but related resistant variant can emerge. In addition, certain variants may thrive in specific tissues or become dominant in an individual because they replicate faster than others. Any of these changes may yield a virus that can escape identification and attack by the immune system."
[Jan 2, 2007 1:11:17 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: HOW FAR ARE WE?

I believe that it is possible to controlate efficently the virus
[Jan 2, 2007 1:24:37 AM]   Link   Report threatening or abusive post: please login first  Go to top 
Former Member
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Re: HOW FAR ARE WE?

Hi jerochan,
Am I right on this?

Correct. Keep in mind that human cells have very efficient anti-retrovirus mechanisms that are disabled by the HIV virus. Other species with slightly different proteins have a similar mechanism that is not disarmed by the HIV virus, so they are effectively immune to HIV. It is an evolutionary arms-race. So there may be a solution that can eventually be found.

Right now we are trying to find new protease inhibitor candidate drugs in FightAIDS@Home.

Lawrence
[Jan 2, 2007 1:46:04 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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