World Community Grid is pleased to launch Human Proteome Folding Phase 2 (HPF2). The goal of HPF2 is to compute higher resolution structures for proteins involved in malaria, recently identified cancer bio-markers, and other key proteins to help better understand their role in living systems and disease processes. For more detailed information and FAQs about HPF2, please press the Research button in the upper navigation bar or click here.

In addition to providing information about this project, we have created a forum for discussions on Human Proteome Folding Phase 2. To participate in this forum, please press the Forums button in the upper navigation bar or click here. Only forum authors with the title "Human Proteome Folding Scientist" are authorized to comment as representatives of New York University (NYU).

HPF2 is one of two projects running on World Community Grid. The other project is FightAIDS@Home, which has been running since November of 2005. For more detailed information and FAQs about FightAIDS@Home, please press the Research button in the upper navigation bar or click here. One other detail to be aware of is that although the first phase of the Human Proteome Folding project was shared with grid.org, HPF2, and all future World Community Grid projects, will only run on World Community Grid.

Because there are two research projects running on World Community Grid, your grid agent could receive work units from either project. You may elect to focus your computer's time on only one of the projects. To do so, press the My Grid button in the upper navigation bar and select My Projects or click here .

HPF2 uses a program called Rosetta, which has been provided to World Community Grid by the project's sponsor, New York University (NYU) through a license with the Rosetta Commons and the University of Washington. Rosetta is a very large computer program and will not run on all PCs or laptops. To see the minimum system requirements for Rosetta, go to Help and search on "System Requirements" or click here . If your PC does not meet the minimum system requirements for HPF2 or FightAIDS@Home, then your agent will show a pause message until a project with smaller work units is available.

If you are already a member of World Community Grid, there's nothing that you have to do to prepare for HPF2. The next time your grid agent communicates with the servers, it will send you either a HPF2 work unit or a FightAIDS@Home work unit. The work unit your computer receives is determined randomly. To know which project you are running, please double-click on World Community Grid's icon in the system tray, and you will see the title of the project on the upper left-hand corner of the agent's homepage.

Members using the UD software will have the standard grid agent graphics showing on their grid agent. Members on the BOINC platforms, including Windows, Linux, and Mac, will not see a graphic on the BOINC Manager. We are working on providing graphics for BOINC and that should be ready soon.

If you have any questions, World Community Grid provides you with four methods of obtaining assistance: (1) Review the FAQs found in the Help section of the website, (2) Review the forums to see if anyone has asked/answered the question that you have, (3) Ask the question in the appropriate member board Forums and a Community Admin or a more experience member will provide an answer, and (4) Send an email to the support desk from the Contact Us link found at the bottom of every page of the website.