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Thread Status: Active Total posts in this thread: 22
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
I see we have also completed stage 1a and 1b of the FightAIDS@Home project also.
----------------------------------------Nice job to all the dedicated cruncher out there in WCG land. Nice job by all on the Human Protein Folding project and the FightAIDS@Home project. ![]() [Edit 1 times, last edit by Former Member at Apr 29, 2006 4:19:28 AM] |
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depriens
Senior Cruncher The Netherlands Joined: Jul 29, 2005 Post Count: 350 Status: Offline Project Badges:
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Great! Thanks a lot for the update and for making it understandable for us!
---------------------------------------- Please try to give us some more of these updates from time to time, really interesting. ![]() |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
mgl_garrett : Thrilled to know about the progress and am happy that there is some progress! That a molecule could be found that binds to all sorts of mutants of HIV. Even though I am circumspect about it, let us do it, lest there is some progress. Please keep on updating us.
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
The same day that the FAAH website was updated to show that 88% of Phase 1a was completed I divided the number of years that have been processed (8,536 years of processing) by 88 percentage points completed and that gave the number of 97 years of processing per percentage point completed. Thus 100% of processing of Phase 1a would take 9,700 years. In the updates given by the FAAH scientists they stated that Phase 1b would take about half as long as Phase 1a thus 1/2 of 9,700 years would be 4,850 years. . Keep in mind that it isnt a 1:1 ratio of work needed : work performed. There is a sloppiness factor involved in grid computing. Say for example, I am 97% through a work unit and my cpu fan fails. (god forbid). My cpu glows like the surface of the sun for a few moments then its gone. this work unit will time out and it will have to be performed again by somebody else. Also, occesionally people actually trn their computers off (or so I have heard) And this could slow down the progress because of duplicated results. (two boxes working on the same WU) |
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Sekerob
Ace Cruncher Joined: Jul 24, 2005 Post Count: 20043 Status: Offline |
"Sloppy" opinions of our "Sloppy" work......there are quite some posts that give all you need to know about the lately optimised redundancy, improving progress 23 to 25% (see the writings by knreed)......
----------------------------------------we cant rush science though, thus, keep crunching and you might make it to advanced or senior cruncher.
WCG
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Actually my estimate for the completion of Phase 1b was fairly accurate. At 88% completion of Phase 1a I estimated it would take 9,700 years of processing to complete Phase 1a. Based on FAAH scientists statements that Phase 1b would take about half as long as Phase 1a I then said that it would take about 4,850 years of processing to complete Phase 1b. In reality the FAAH scientists announced that Phase 1b had been completed at about 14,400 years of total processing (about 4,700 years of processing Phase 1b), so my estimate was fairly close (within a few days of processing time to reach 4,850 years).
In Phase 2 judging from the amount of data that is needed to be processed and from the time it took to to process Phases 1a and 1b a good ball park guess would be that Phase 2 will take between 12,000 and 13,000 years of total processing, with completion occuring in late August or September. This assumes that the present processing rate is maintained. Hotter summertime weather in the Northern Hemisphere might cause some users to reduce computer usage due to overheating. Regardless, the estimated Phase 2 completion time frame includes situations where individual work units are not completed due to user system problems and where work units are never returned for other reasons, assuming the same proportion of non-returned work units occurs in Phase 2 as did in Phases 1a and 1b. At this moment we have processed almost 4,400 years of data in Phase 2. This means that Phase 2 is about between 34% and 37% completed. |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Just to be complete here are the specific estimates of the required years of processing for Phase 2 based on the past processing times required to complete Phases 1a and 1b:
----------------------------------------Processing ChemBridge (500,000) vs. Wild Type HIV Protease (1) will take about 10,200 to 10,300 years. Processing NCI Diversity Set (1,900) vs. Monomeric HIV Protease (20) will take about 720 years. Processing Top Hits from Stage 1 vs. Mutant HIV Protease Panel (270) at this time is unknown since the FAAH scientists have not disclosed the exact number of Top Hits. I have allocated between 1,000 and 2,000 years to complete this but this is only a guess. This totals out to be between 12,000 and 13,000 years but it could be a bit more or less (most likely less) depending on how many Top Hits are processed. Regardless, an August or September time frame for completion seems reasonable. [Edit 2 times, last edit by Former Member at Jun 12, 2006 1:34:30 AM] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Here's the link for anyone who would like to check out the FightAids@Home Page: http://fightaidsathome.scripps.edu/
This will give you our progress. NICE WORK BY ONE AND ALL!!!! |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
"Sloppy" opinions of our "Sloppy" work......there are quite some posts that give all you need to know about the lately optimised redundancy, improving progress 23 to 25% (see the writings by knreed)...... we cant rush science though, thus, keep crunching and you might make it to advanced or senior cruncher. Perhaps "sloppy" was a bad term. I meant no offense. I meant to say that for every 100 WU you send out, you dont get 100 Results back. So it is safe to say that some WU never get finished because of attrition, and some don't get done because of hardware issues. So the overall ratio of wu sent out : results received is less than 100% no? ![]() |
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retsof
Former Community Advisor USA Joined: Jul 31, 2005 Post Count: 6824 Status: Offline Project Badges:
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"Sloppy" opinions of our "Sloppy" work......there are quite some posts that give all you need to know about the lately optimised redundancy, improving progress 23 to 25% (see the writings by knreed)...... we cant rush science though, thus, keep crunching and you might make it to advanced or senior cruncher. Perhaps "sloppy" was a bad term. I meant no offense. I meant to say that for every 100 WU you send out, you dont get 100 Results back. So it is safe to say that some WU never get finished because of attrition, and some don't get done because of hardware issues. So the overall ratio of wu sent out : results received is less than 100% no? ![]() There's also a time element. If three units haven't been returned in a week, WCG sends out a fourth. I suspect that it would keep doing that until there are three results to average. I have seen at least three other projects out there with a quorum of 1. They send you a workunit. When it finishes, you send it in and get instant credit. There is no averaging involved. It seems to be the mathematical and numerical projects.
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