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Jim Slade
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Re: Interesting news articles about AIDS

Anthony Fauci, MD: Working to End HIV/AIDS

Just weeks before the 22nd International AIDS Conference Anthony Fauci, MD, the director of the National Institute of Allergy and Infectious Diseases at NIH spoke with JAMA about how far we've come in treating and preventing HIV/AIDS - and how much further we need to go to reach his ultimate goal of eliminating the disease.

https://jamanetwork.com/journals/jama/fullart...t=olf&utm_term=071118


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Jim Slade
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Re: Interesting news articles about AIDS

International AIDS Conference (AIDS) 2018

July 23-27, 2018, HIV.gov will report from the 22nd International AIDS Conference (AIDS 2018). 15,000 global leaders, policy makers, HIV researchers, and advocates will share updates on the latest developments in HIV prevention, care, and treatment.

http://www.hiv.gov/blog/tune-next-week-covera...rnational-aids-conference


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Jim Slade
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Re: Interesting news articles about AIDS

Why Are Scientists So Upset About the First Crispr Babies?

Only because a rogue researcher defied myriad scientific and ethical norms and guidelines. We break it down.

https://www.nytimes.com/2018/12/05/health/crispr-gene-editing-embryos.html


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Papa3
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Re: Interesting news articles about AIDS

Researchers have launched an ultra-large virtual docking library expected to grow to more than 1 billion molecules by next year. It will expand by 1000-fold the number of such "make-on-demand" compounds readily available to scientists for chemical biology and drug discovery. The larger the library, the better its odds of weeding out inactive "decoy" molecules that could otherwise lead researchers down blind alleys.

A staggering number of potential drug-like molecules are known to exist. Yet, hundreds-of-millions to billions of diverse molecules have remained inaccessible due to limitations of existing methods used to compile molecular libraries, say the researchers. For example, their virtual structure-based docking technique, while promising, risks finding many false positives or "decoys" -- flaws in the model allow for molecules that appear plausible but turn out to be biologically inactive.

To overcome this challenge, the researchers focused on molecules that result from 130 well-characterized chemical reactions using 70,000 different chemical building blocks. Computer simulations with these molecules showed that as the size of a library grew, the ratio of "true actives" to decoys increased -- just as a study's statistical power increases with a larger sample.


https://www.sciencedaily.com/releases/2019/02/190206131924.htm
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Papa3
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Re: Interesting news articles about AIDS

Moderna – famed for its Covid-19 vaccine – may have finally cracked an HIV vaccine. The jab uses sophisticated gene-editing technology to train the immune system to produce a variety of HIV-like particles, to familiarise the body with many mutations. It is currently undergoing human trials.


https://www.dailymail.co.uk/health/article-92...illion-global-deaths.html
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Jim Slade
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Re: Interesting news articles about AIDS

Dr. Anthony Fauci on the beginning of the AIDS response

https://us6.campaign-archive.com/?u=3746d12bb...69414a51&e=e4dc4b8d2b


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Jim Slade
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Re: Interesting news articles about AIDS

IAS Annual Letter 2021 - Follow the Science

https://followthescience.iasociety.org/


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Jim Slade
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Re: Interesting news articles about AIDS

Audio Interview: Dr. Fauci on Infectious Disease Challenges

Anthony Fauci is the former U.S. Chief Medical Advisor and Director of NIAID.

https://www.nejm.org/doi/full/10.1056/NEJMe2307011?query=NC
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Jim Slade
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Re: Interesting news articles about AIDS

PEPFAR at 20 - A Game Changing Impact on HIV in Africa | NEJM

Interview with Jean Nachega on PEPFAR's achievements and remaining challenges in HIV prevention and treatment in sub-Saharan Africa.

Jean Nachega is an associate professor of infectious diseases and microbiology and epidemiology at the University of Pittsburg School of Public Health and a professor of medicine at Stellenbosch University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal.

https://www.nejm.org/doi/full/10.1056/NEJMp2304600
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Jim Slade
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Re: Interesting news articles about AIDS

Threatening the Global AIDS Response - Obstacles to PEPFAR's Reauthorization | NEJM

https://www.nejm.org/doi/full/10.1056/NEJMp2310330
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