| Index | Recent Threads | Unanswered Threads | Who's Active | Guidelines | Search |
| World Community Grid Forums
|
| No member browsing this thread |
|
Thread Status: Active Total posts in this thread: 30
|
|
| Author |
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
HIV and AIDS is here. It's killing people now. It has been around for thirty years (I contracted it 23 years ago through my haemophilia treatment - I was 5 years old at the time) and it's not going away any time soon.
It doesn't matter anymore where it came from. What matters is that we have the power to help people suffering from it. To prolong lives. This project is helping to reduce the cost of (and reduce the time doing) research in medicine by such an amount that more people will be able to have access to medicines than has ever happened before. How the virus came about doesn't seem relevant anymore. If said "scientist" exists, and is holding a cure for this thing, then they have held it for years against the prevention of the loss of millions of lives... they won't give it up any time soon. Let's get on with treating people... at least that's in our power to do. |
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Sorry to hear that you have aids, but on a good note, there is a group of people that have immunity to HIV. That is, they lack the receptors on their cell surface that would allow the virus access. Scientist are studying these people to see if we could do without this receptor. If it turns out that the receptor has no other vital function, then drugs could be made to bind with this receptor and block the virus from carrying out its function (reverse transcriptase) allowing the virus to pass harmlessly through us. We would be carriers still, but would be unaffected by the virus. My only other concern with blocking a virus , would be to the possibility of mutation as an adaptation to the block… Anyway, there is hope and a need for further testing and research beyond the cure.
|
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Thanks for your reply Arnold. I am aware of several up and coming treatments, fusion inhibitors, that work in the way that you suggest, by binding with CD4 receptors in order to disallow the HIV virus access to the T cells themselves. All previous treatments to do with reverse transcriptase (nucleoside analogue, non-nucleoside, nucleotide) and protease work at disrupting the replication process of the virus once it is already inside the cell. Fusion inhibiton seems to be the way to go as it would, given 100% coverage of all CD4 receptors (and barring mutations that would enable the virus to use other receptors), allow the virus to pass through us as you say.
And as a single virus has a "shelf-life" if you like, no replication means the eventual eradication of the virus from the bloodstream. "Undetectable viral load" may soon mean "Zero viral load" instead of "less than 50 copies per ml of blood" There are so many fronts on which to attack the virus. This project is working on protease inhibition... maybe the next one could work on fusion inhibition? |
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
AMERICANS HAVE CREATED AIDS VIRUS! ??
The AIDS pathogen was created out of a Brucella bacterium mutated with a visna virus; then the toxin was removed as a DNA particle called a mycoplasma. They used the same mycoplasma to develop disabling diseases like MS, Crohn's colitis, Lyme disease, etc. http://nexusmagazine.com/articles/mycoplasma.html |
||
|
|
retsof
Former Community Advisor USA Joined: Jul 31, 2005 Post Count: 6824 Status: Offline Project Badges:
|
MS=Microsoft
----------------------------------------Crohn's colitis, not crone's coalitis Lyme disease takes a licking, and keeps on ticking. They?
SUPPORT ADVISOR
----------------------------------------Work+GPU i7 8700 12threads School i7 4770 8threads Default+GPU Ryzen 7 3700X 16threads Ryzen 7 3800X 16 threads Ryzen 9 3900X 24threads Home i7 3540M 4threads50% [Edit 1 times, last edit by retsof at Dec 5, 2005 2:57:30 PM] |
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Any time mouse : ) … Looks as if you have been doing your homework. I agree that inhibiters are better than the disruptive treatments. The problem with disrupting the virus replication process is that it also disrupts cellular replication, which has its own set of problems including cancerous development. Once an effective treatment is found, the reduction would follow however, a virus has the unique ability to take on a crystalline state allowing it to sit dormant. This is similar to endospores created by gram-positive bacteria. They sure don’t wish to go down with out a fight… : (
|
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Hello mates! I am coming back again. I am sorry for my article if I make somebody upset. Anyway I would like to thanks you all that advise me whether to understand more about life and that discease. I am now very fine and know well how to lead my life. We are not the AIDS victim. We have to be responsible on whatever we did for the sake of ourself.
Alternative therapies would be the kind of help, especially the therapy related to the inside body or mind. I hope i would have ability to help my people in a few year later. |
||
|
|
Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
You guys are twisted. THis nonsense comes from not understanding something. And there is NO victim with HIV, unless you got hit by a car and was given bad blood. I also have HIV, I got it when I was 16 coz I didnt protect myself and thought with my penis, not my brain, I am not a victim, I was a protagonist coz I never took care of myself. So, dont make a victim out of this, thats being selfish, my family is going to hurt long after I am dead. So, if you wanna think about victimization, think of your family while you are still here and start living. But who the hell am I trying to kid? I got when I was 16, im 32 now. No one made me a victim, and I refuse to be a victim. -- This post has been edited for profanity - nelsoc thats a good attitude twords life man, as long as you dont remind yourself every day you did something wrong and you are paying for it and ... if all you could do as a peerson is find the truth of "your so called desease" you would realize much more . I admire your courage .yet why not try to find the specifics wich make you sick rather than swollowing chain terminator drugs ... the Aids syndrome is a psychological syndrome in part , if i tell someone that they have aids I will for sure cut alot of years just by stresing them to realise every day that they will die , we all die , you got aids but there will be people dieing before you do and they have noone to tell them . I suggest you all try to find out specifics on Aids and . That<Gallo dude he must be the one benefiting from all the aimless rable . ![]() |
||
|
|
BertrandRussel
Cruncher Joined: Nov 24, 2006 Post Count: 30 Status: Offline Project Badges:
|
Oh, it seems that there is a crunchy little cyber war going on those seemingly peaceful WCG pages...
----------------------------------------Dear paranoiacs, go spreading your mental viruses somewhere else and let reasonable people focus on their task! We didn't come here to spend our CPU time for infecting other's minds. And stop blaming innocent people for problems that they are not responsible for. Also, there is no such thing as clan liability in modern society - it's a horrific middle age concept. Thank you. [Edit 1 times, last edit by BertrandRussel at Jun 2, 2007 10:02:17 AM] |
||
|
|
twilyth
Master Cruncher US Joined: Mar 30, 2007 Post Count: 2130 Status: Offline Project Badges:
|
Glad that you're still with us - and crunching even - congratulations.
----------------------------------------Everyone gets angry when something terrible happens to us - it's a normal human reaction. It's good that you've gotten past that and are looking to the future. Slowly, too slowly for many, AIDS is becoming more a chronic disease than a death sentence. By now I'm sure you realize that. So there is more hope now than ever. Good fortune and good health to you and your family. ![]() ![]() |
||
|
|
|