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World Community Grid Forums
Category: Active Research
Forum: Mapping Cancer Markers Forum
Thread: Clinical use? |
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Thread Status: Active Total posts in this thread: 18
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mwroggenbuck
Advanced Cruncher USA Joined: Nov 1, 2006 Post Count: 77 Status: Offline Project Badges: 
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Hello,
----------------------------------------I know that the MCM project has published numerous papers. I am curious. Have any of these papers been applied in clinical use? Have the results influenced the diagnosis or care of someone? In other words, has this project helped save lives? I ask because I would like to know if there have been concrete results or if everything is still theoretical. I want to stress that I am not making any judgements here. Like I said, I am just curious how far along this work has gone. Mark [Edit 1 times, last edit by mwroggenbuck at Jan 8, 2024 12:37:58 PM] |
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Falconet
Master Cruncher Portugal Joined: Mar 9, 2009 Post Count: 3295 Status: Offline Project Badges: 
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Based on everything that has been posted by the project, the answer is no.
----------------------------------------May my post serve as a bump for a scientist to answer, though. AMD Ryzen 5 1600AF 6C/12T 3.2 GHz - 85W AMD Ryzen 5 2500U 4C/8T 2.0 GHz - 28W AMD Ryzen 7 7730U 8C/16T 3.0 GHz |
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mwroggenbuck
Advanced Cruncher USA Joined: Nov 1, 2006 Post Count: 77 Status: Offline Project Badges:
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Waiting for a response.
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grayon
Cruncher Joined: Nov 16, 2004 Post Count: 18 Status: Offline Project Badges:
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some researchers might consider the elimination of millions of non-starters as important as a group probable hits. Don't kown if the bean-counters would go out of their way to emphasize it. Again..no judgement implied.
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TigerLily
Senior Cruncher Joined: May 26, 2023 Post Count: 280 Status: Offline Project Badges: 
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Hi mwroggenbuck,
Sorry for the delay in responding to this! From the current MCM runs, the work on analyzing results is still in progress. For example, see the most recent update on lung cancer biomarkers. However, the team's research has led to various publications over the years. MCM's work surrounds identifying cancer biomarkers, and it can take many years for this research to shape clinical practice. |
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mwroggenbuck
Advanced Cruncher USA Joined: Nov 1, 2006 Post Count: 77 Status: Offline Project Badges:
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Thank you for the reply.
----------------------------------------I suspected things were still at the theoretical and investigative stage for the current work. As you pointed out though, several publications have been produced over the years. Have any of these earlier published results been used in clinical practice? Again, thanks for the response about current work.. Mark [Edit 4 times, last edit by mwroggenbuck at Jan 16, 2024 12:51:34 PM] |
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TigerLily
Senior Cruncher Joined: May 26, 2023 Post Count: 280 Status: Offline Project Badges:
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Hi mwroggenbuck,
MCM work completed through WCG has not been implemented into clinical practice yet. However, some of the Jurisica lab's other work on biomarkers has had an impact on clinical practice. |
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mwroggenbuck
Advanced Cruncher USA Joined: Nov 1, 2006 Post Count: 77 Status: Offline Project Badges:
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Excellent news!
Keep up the good work! It would be nice to live in a world where cancer was easily treatable. Maybe this is a step in that direction. Thanks for the response. I will stop pestering you now.  Mark |
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TigerLily
Senior Cruncher Joined: May 26, 2023 Post Count: 280 Status: Offline Project Badges:
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Hi mwroggenbuck,
No problem! We appreciate that volunteers are curious and passionate about the cause! |
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Spiderman
Advanced Cruncher United States Joined: Jul 13, 2020 Post Count: 116 Status: Offline Project Badges: 
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mwroggenbuck -- A few years back, Chiba Cancer Center in Japan announced they'd narrowed a list of molecules down to (7) potential drugs to help defeat childhood neuroblastoma based on the work done at WCG. They published their work and at that time were looking for a potential pharmaceutical partner.
----------------------------------------https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.175 https://www.worldcommunitygrid.org/about_us/article.s?articleId=341 -- Looking at broader BOINC Projects, Rosetta (non-WCG) had positive results from BOINC volunteers' efforts getting a COVID vaccine identified and produced. It had a high effective rate and outperformed the AstraZeneca vaccine. https://www.ipd.uw.edu/2022/06/covid-19-vacci...ins-full-approval-abroad/ -- There are others, but the above two immediately came to mind as far as how our efforts are helping mankind. [Edit 1 times, last edit by Spiderman at Jan 19, 2024 3:00:56 PM] |
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