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Tiagomartins
Cruncher Joined: Feb 24, 2014 Post Count: 27 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() |
Good afternoon. I have seen that the project is firm, but the increase in new contributors has been small. We are all going to invite more people to the project, because it is really worth helping the scientists who have helped us so much. share the project with as many people as you can.
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Mike.Gibson
Ace Cruncher England Joined: Aug 23, 2007 Post Count: 12480 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
As there are only about 3-6 months left for the current target, I would hold off from a recruitment drive until we get confirmation that there will be further targets once we reach batch 50,000.
Techs, how about some confirmation, please? Mike |
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ThreadRipper
Veteran Cruncher Sweden Joined: Apr 26, 2007 Post Count: 1322 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Yes, at the same time...considering the amount of time that has been invested in developing the GPU side of tings I would suspect target 1 is only the first in a long row of targets.
----------------------------------------But as you say Mike, some confirmation would be good. ![]() Join The International Team: https://www.worldcommunitygrid.org/team/viewTeamInfo.do?teamId=CK9RP1BKX1 AMD TR2990WX @ PBO, 64GB Quad 3200MHz 14-17-17-17-1T, RX6900XT @ Stock AMD 3800X @ PBO AMD 2700X @ 4GHz |
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Martin Schnellinger
Advanced Cruncher Joined: Apr 29, 2007 Post Count: 123 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Hello,
if someone is invited to covid project only, it would be good to know, how much work is left for covid project only. On the other hand, there are many other good projects to choose from. And, last, if we had much more contributions to covid project, it maybe would end only in two weeks already. And this would be positive, woudn't it. As far as I am concerned I will contribute as long as I can. If covid ends I go to immune projects. Best Martin |
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Kinwolf
Cruncher Joined: Feb 22, 2011 Post Count: 11 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
In any case, saying anyone should wait to try to recruit and get more help on a time-sensitive crisis like this one is not really logic. So what if the 6 months workunits get spent in 2 months instead, isn't that even better if one candidate turn out to be the one that will help save life?
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Mike.Gibson
Ace Cruncher England Joined: Aug 23, 2007 Post Count: 12480 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
I was really just trying to provoke the techs into giving some sort of idea how long opn might last.
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cjslman
Master Cruncher Mexico Joined: Nov 23, 2004 Post Count: 2082 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
I’m pretty sure that this project has plenty of WUs to crunch. There are already mutations of the virus being formed in the wild, which may need other/different treatments. Unfortunately, I don’ see this pandemic ending soon.
----------------------------------------CJSL Crunching for a better world... |
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Falconet
Master Cruncher Portugal Joined: Mar 9, 2009 Post Count: 3297 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
I was really just trying to provoke the techs into giving some sort of idea how long opn might last. IIRC, they said every protein of the virus was a target. I seem to remember writing a post saying that there were around 30 proteins or something, so around 30 targets. Each target was said to have 50,000 batches. I also recall the word "huge" being used to describe this project. My guess is we've barely begun but we'll probably get more info once the GPU version launches, whenever that is. Edit: From the launch post : "This will allow us to target not only the whole viral proteome (i.e. every protein made by the virus) but also their interactions with the host proteins" AMD Ryzen 5 1600AF 6C/12T 3.2 GHz - 85W AMD Ryzen 5 2500U 4C/8T 2.0 GHz - 28W AMD Ryzen 7 7730U 8C/16T 3.0 GHz [Edit 2 times, last edit by Falconet at Feb 7, 2021 2:21:15 PM] |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
That is very helpful. But some proteins must be better targets than others, and hopefully they are targeting them first. I would like to see some progress reports from their lab tests, and when they might begin some field trials. By the time we go through all 1.5 million of them, a new virus will have emerged.
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Falconet
Master Cruncher Portugal Joined: Mar 9, 2009 Post Count: 3297 Status: Offline Project Badges: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
That is very helpful. But some proteins must be better targets than others, and hopefully they are targeting them first. I would like to see some progress reports from their lab tests, and when they might begin some field trials. By the time we go through all 1.5 million of them, a new virus will have emerged. In the July 2020 update, they mentioned that they were, at the time, focusing on 3 different target proteins. "In the initial phase of the project, we are focusing our effort against 3 protein targets of SARS-CoV-2: the papain-like proteases (PLpro, or nsp3), the main protease (Mpro, or nsp5) and the endoribonuclease (nsp15)." AMD Ryzen 5 1600AF 6C/12T 3.2 GHz - 85W AMD Ryzen 5 2500U 4C/8T 2.0 GHz - 28W AMD Ryzen 7 7730U 8C/16T 3.0 GHz [Edit 1 times, last edit by Falconet at Feb 7, 2021 4:13:51 PM] |
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