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Thread: Researchs on potential drugs for treating NCov (new coronavirus Wuhan 2019-2020) |
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Thread Status: Active Total posts in this thread: 16
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Hi,
Did a project exist about researching drugs best suiteds treating the new coronavirus I see some researchers have published the full genome in open acces, abd also they have made a research about anti-protease drugs targeting this new coronavirus, i took them 23 or 27 days i dont remember to find like 10 drugs suited for this. If anyone have the knowledge to do a project for helping them researching best suites drugs and not only the conventional one if we have good computer power we can include many molecule and like terpenes in essential oils, and also tryeven to find a new drug with the best activity and not only for antiprotease drugs but for all other drugs that can break the virus replication process, i'mnot biologist but i know antiprotease is not the only way to block virus to replicate. sing virtual screening is a fast method to test many molecule or protein ( as i say im not bbiologist) against different virus bacteria pathology So please IF soeone know people in this field of research talk to them about World community grid and gridcoin in general e can help people rapidly if everybody go on this crucial Thanks and if you can make a tweet about this post so a maximum of people will know they can help fight N(Cov) 2019 |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Another case of an illness born from animals and humans living in too close proximity. Eventually the bugs get to mutate and survive.
----------------------------------------https://www.washingtonpost.com/world/coronavi...2-090eb37b60b1_story.html [Edit 1 times, last edit by Former Member at Jan 25, 2020 11:53:53 PM] |
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hchc
Veteran Cruncher USA Joined: Aug 15, 2006 Post Count: 865 Status: Offline Project Badges: 
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Edit 2/27/20: I could be eating my words. Covid-19 worries me.
--------------------------------------------------- Original Post ----------- OP, this epidemic will be long forgotten by the time any distributed computing project on the BOINC platform can be designed, funded, executed, and completed, if history of BOINC projects' snail-like progress is of any significance. In other words: fat chance. There's no ROI. ~3% mortality rate isn't high enough to secure funding for actual scientific research. Those that die are largely the elderly and those with existing comorbid disease, not healthy people. (In other words, coronavirus infection does not in itself kill people despite being easily transmitted from human to human. This is a good thing. Contrast this with Ebola virus, which kills greater than 9 out of 10 perfectly healthy humans.) Government spending on the Wuhan coronavirus is largely focused on quarantine and infection control measures as well as treatment of the disease and other comorbidities, not on drug therapy, vaccine, or anything that would even remotely be designed as a distributed computing or supercomputing project.
[Edit 2 times, last edit by hchc at Feb 28, 2020 2:23:25 AM] |
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l_mckeon
Senior Cruncher Joined: Oct 20, 2007 Post Count: 439 Status: Offline Project Badges: 
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Vaccine design for Wuhan virus is underway in three centers around the world and a local lab said last week that they expect to have a working design in 16 weeks.
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Bump
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gb009761
Master Cruncher Scotland Joined: Apr 6, 2005 Post Count: 3010 Status: Offline Project Badges: 
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Now, this may sound contraversial (and probably goes against the idea behind WCG), but perhaps this planet needs a virus that decimates the population - as, after all, can the human population survive on this planet when we're at ~7.7 Billion, with estimates of over 10 Billion???
----------------------------------------Less people on this rock, equals less polution, less food having to be grown (including animals to feed us all, and food to feed the animals), a possible chance (albeit slim) to keep the climate under control, and, in the future, less chance of wars breaking out - due to the lack of land to accommodate everyone. Basically, the 'elephant in the room', is that there are just far too many people on this planet. Now, don't get me wrong, I'm not going to quit WCG (nor try to encourage anyone else), as I still do believe that we can turn things around, but seeing all the plastic polution, climate change (whether you believe in it or not) and the rapid increase in extinctions across the world, just goes to show that the whole world needs to come together and work as one, FAST!!!!  |
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Jim1348
Veteran Cruncher USA Joined: Jul 13, 2009 Post Count: 1066 Status: Offline Project Badges: 
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Rosetta is making a stab at it (a treatment, not a vaccine I think).
http://boinc.bakerlab.org/rosetta/forum_threa...10&postid=91696#91696 There is probably room for more than one, especially if there are mutations. |
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Falconet
Master Cruncher Portugal Joined: Mar 9, 2009 Post Count: 3315 Status: Offline Project Badges:
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Thanks Jim.
---------------------------------------- - AMD Ryzen 5 1600AF 6C/12T 3.2 GHz - 85W - AMD Ryzen 5 2500U 4C/8T 2.0 GHz - 28W - AMD Ryzen 7 7730U 8C/16T 3.0 GHz |
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Crystal Pellet
Veteran Cruncher Joined: May 21, 2008 Post Count: 1407 Status: Recently Active Project Badges: 
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A 85 years old antimalarial drug confirmed to have a certain curative effect on COVID-19
BEIJING, Feb. 17 http://www.xinhuanet.com/english/2020-02/17/c_138792545.htm |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Now, this may sound contraversial (and probably goes against the idea behind WCG), but perhaps this planet needs a virus that decimates the population - as, after all, can the human population survive on this planet when we're at ~7.7 Billion, with estimates of over 10 Billion??? You are certainly right, that there are too many people on this planet. However, experience shows, that this cannot be solved by letting people die from diseases. Worldwide, the regions with the highest death rates from diseases have also the highest birth rates and population growth rates (which is more or less only Sub-Saharan Africa now, birth rates have slowed down dramatically in almost all other parts of the world). Which seems counter-intuitive at first, works best for population control: decrease death rates by improving health, which leads to better living conditions, better education and decreasing birth rates over time. While many people dying prematurely often leads to exploding birth rates and the opposite effect. |
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