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Former Member
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Re: Not even a welcome post, so welcome Zika Reaearchers

I've already gotten two resends on an android device where there were errors from the previous crunchers. High error rates on android? I'm not home so I can't check the device that has queued them at the moment.

Edit: This was the message in all the other error crunchers:
Result Name: ZIKA_ 000000058_ x4wtg_ HCV_ NS5B_ 5muts_ wRNA_ 0060_ 1--

<core_client_version>7.4.14</core_client_version>
<![CDATA[
<message>
process got signal 11
</message>
<stderr_txt>

</stderr_txt>
]]>
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[Edit 1 times, last edit by Former Member at May 18, 2016 7:28:26 PM]
[May 18, 2016 7:25:56 PM]   Link   Report threatening or abusive post: please login first  Go to top 
seippel
Former World Community Grid Tech
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Re: Not even a welcome post, so welcome Zika Reaearchers

On the variable runtimes, thought armstrdj had 'machine learned' during beta23 how to package N jobs in a task to get them to run an objective target time?


The production workunits were built using runtime information collected during beta, however beta only contains information for a subset of the types of ligands for this project. As a result, we are expecting variations in runtime for the first few weeks (or even months) of this project. As more work units are returned, the runtime estimates should continue to get more exact.

Seippel
[May 18, 2016 8:01:25 PM]   Link   Report threatening or abusive post: please login first  Go to top 
9maMSSuNWXgttyKdZhMemeXmEx8
Senior Cruncher
Puerto Rico
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Re: Not even a welcome post, so welcome Zika Reaearchers

139 workunits and they keep coming!!! Yes!!!
----------------------------------------


[May 18, 2016 10:56:56 PM]   Link   Report threatening or abusive post: please login first  Go to top 
mgl_ALPerryman
FightAIDS@Home, GO Fight Against Malaria and OpenZika Scientist
USA
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applause Re: Not even a welcome post, so welcome Zika Researchers

Hi Everybody,

Thank you all very much for your enthusiastic support and for contributing to this project right from the start (and during the beta tests, apparently).

Well done, Falconet! You figured out what the new project was while it was still in the "confidential phase" of beta tests. Since I used the same naming convention for the targets that I used in GO FAM, the PDB ID's might have been the clue. ;) (Then again, I think I actually put Dengue and WestNile in some of the target names, which wasn't exactly very stealthy of me.)

I'm glad to see that you and so many of the other volunteers are still contributing, after many years of crunching away. Kudos!

Cheers,
Dr. Alex L. Perryman
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[Edit 1 times, last edit by mgl_ALPerryman at May 19, 2016 12:33:07 AM]
[May 19, 2016 12:19:38 AM]   Link   Report threatening or abusive post: please login first  Go to top 
mgl_ALPerryman
FightAIDS@Home, GO Fight Against Malaria and OpenZika Scientist
USA
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Re: Not even a welcome post, so welcome Zika Reaearchers

Good evening SekeRob*,

Thank you very much!

When Dr. Sean Ekins started assembling a group of collaborators to work on Zika, I felt compelled to help out. He has taught me a lot in the last two and a half years, and I had to return the favor in some way. Regardless, I am happy to be helping such a worthy cause. Sean will post a blog about the origins of this project tomorrow, so be on the lookout.

In just a few months, he assembled quite the multi-disciplinary, multi-national team of scientists to advance this project. It went from the idea, to submitting the proposal to IBM, to launching this project in record speed! Fresh paint / new car smell is quite right.

Cheers,
Dr. Alex L. Perryman
[May 19, 2016 12:30:13 AM]   Link   Report threatening or abusive post: please login first  Go to top 
Jack007
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CANADA
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Re: Not even a welcome post, so welcome Zika Researchers

It runs on Android biggrin


TY FOR POINTING THAT OUT,
I hadn't noticed yet,
My phone is just working on Ebola,
so this will give it something else to chew on as well. biggrin
----------------------------------------

[May 19, 2016 1:26:49 AM]   Link   Report threatening or abusive post: please login first  Go to top 
pvh513
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Re: Not even a welcome post, so welcome Zika Researchers

Wow, already got 276 WUs before I could blink an eye...! 23 have finished so far, all in PV jail. Run times seem quite consistent for these first WUs: 1.4-1.6 hours on my Core i7-2600 and 1.7-1.9 hours on my Xeon E5-2630 v3, both with hyperthreading enabled. This is on linux.
[May 19, 2016 6:28:36 AM]   Link   Report threatening or abusive post: please login first  Go to top 
Rickjb
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Australia
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Re: Not even a welcome post, so welcome Zika Researchers

Greetings Dr Perryman and welcome back to being visibly active in research projects at WCG.

Screening with AutoDock and/or VINA for drug candidates against HIV as was done in FAAH Phase 1, and against flaviviridae other than Zika as was done in DDDT Phase 1, produced unacceptable numbers of false positives. In Phase 2 of FAAH, the BEDAM software is being used in an attempt to filter out the false positives.
In DDDT, filtering out the false positives with the CHARMM program was tried, but seems to have failed.

Can we not expect that VINA will produce too many false positives for drugs against Zika? If indeed this is the case, are measures in place to try to filter them out, using BEDAM for example? Could the DDDT results be useful in trying out these measures? Is that what the current screening in the Zika project using VINA against flavivirus HCV is about?

Here's hoping for some breakthroughs in the search for drugs to inhibit these viruses (or is that viridae?)
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[Edit 2 times, last edit by Rickjb at May 20, 2016 12:46:47 AM]
[May 19, 2016 8:52:18 AM]   Link   Report threatening or abusive post: please login first  Go to top 
KLiK
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Croatia
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Re: Not even a welcome post, so welcome Zika Researchers

I thought it stood for Make Description Deceive SekeRob laughing

laughing crying laughing
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non-profit org. Play4Life in Zagreb, Croatia
[May 19, 2016 8:56:04 AM]   Link   Report threatening or abusive post: please login first  Go to top 
KLiK
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Croatia
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Re: Not even a welcome post, so welcome Zika Reaearchers

On the variable runtimes, thought armstrdj had 'machine learned' during beta23 how to package N jobs in a task to get them to run an objective target time?


The production workunits were built using runtime information collected during beta, however beta only contains information for a subset of the types of ligands for this project. As a result, we are expecting variations in runtime for the first few weeks (or even months) of this project. As more work units are returned, the runtime estimates should continue to get more exact.

Seippel

do we know "the total number of batches" in ZIKA?
----------------------------------------
oldies:UDgrid.org & PS3 Life@home


non-profit org. Play4Life in Zagreb, Croatia
[May 19, 2016 8:59:44 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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