Thanks for the update, mgl_ALPerryman. There's nothing like keeping the troops informed and with that -- engaged and 'locked on' to the science-target.
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The FAAH volume 11 PDF does not want to download. Is this just a temporary problem? If it works for you, please post here.


Lawrence

The current newsletter talks about the findings from Experiment 30. We are now working on experiment 41. It would be very welcomed to hear what sort of progress and discoveries have been made in Experiments 31 through 40. I can imagine that it takes months, if not years to analyze the results, and we as crunches like to hear how our results contributions are helping the project out.

Hi herflick,

Although I have processed and measured the results for Experiments 31 to 40, I have not yet had a chance to filter them and visually inspect the top-ranked compounds. After discovering these promising hits in Experiment 30, I've been focusing on hit-to-lead development (that is, trying to use the structures of these hits to guide the process of making larger, more potent compounds). I've also been spending a lot of time on the GO Fight Against Malaria project: preparing targets, performing and analyzing positive control studies, submitting experiments, and processing their results. I've also visually inspected and ordered new candidate compounds against two different classes of targets from the GO Fight Against Malaria project: PfSUB1 and InhA from Mycobacterium tuberculosis (which is very similar to ENR from malaria). I only need to prepare a few more classes of targets against malaria, and then I'll have more time to devote to analyzing the results of the other FightAIDS@Home experiments.

I will visually inspect and order compounds from FightAIDS@Home experiments 31 to 40, but it will take time.

Thank you very much for your interest and your support,
Alex L. Perryman, Ph.D.