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World Community Grid Forums
Category: Completed Research
Forum: FightAIDS@Home
Thread: FA@H Project Status Update |
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Thread Status: Active Total posts in this thread: 14
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TKH
Former World Community Grid Admin USA Joined: Aug 13, 2005 Post Count: 775 Status: Offline Project Badges: 
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Randzo
Senior Cruncher Slovakia Joined: Jan 10, 2008 Post Count: 339 Status: Offline Project Badges: 
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77% complete well done.
Go on. |
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Rickjb
Veteran Cruncher Australia Joined: Sep 17, 2006 Post Count: 666 Status: Offline Project Badges: 
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Thanks for notifying us of the FAAH Status Page update, TKH.
----------------------------------------The last batch number mentioned there is faah11646 (Experiment 31: 77% Completed, involves faah8972 - faah11646). Batches are usually despatched in numerical order, and I now have some faah11547 WUs in one of my queues. At the current rate, we will receive all of faah11646 within about 1 week. What's next? [Edit]: Batches faah11647 - faah13,984. See below. [Edit 1 times, last edit by Rickjb at Mar 29, 2010 9:41:57 AM] |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Thanks for notifying us of the FAAH Status Page update, TKH. The last batch number mentioned there is faah11646 (Experiment 31: 77% Completed, involves faah8972 - faah11646). Batches are usually despatched in numerical order, and I now have some faah11547 WUs in one of my queues. At the current rate, we will receive all of faah11646 within about 1 week. What's next? http://www.worldcommunitygrid.org/forums/wcg/printpost_post,265834 1/19/2010 We have not yet performed any FAAH experiments against HIV integrase. After 1 to 3 more experiments against HIV protease, we plan to submit experiments focused on HIV integrase. |
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Rickjb
Veteran Cruncher Australia Joined: Sep 17, 2006 Post Count: 666 Status: Offline Project Badges:
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The FAAH Status Page has been updated again:
> Last modified: 3/26/2010 by Alex Perryman, Ph.D. The heading at the top of the Page still says "Project Status, as of March 16, 2010", but a new experiment, #32, has been described. It will involve batches faah11647 - faah13,984. And no, we won't be working on integrase yet. |
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mgl_ALPerryman
FightAIDS@Home, GO Fight Against Malaria and OpenZika Scientist USA Joined: Aug 25, 2007 Post Count: 283 Status: Offline Project Badges:
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Hi Rickjb and fellow crunchers,
I always focus on keeping the queue full first, and then I take the time to update the experiment descriptions and % completion statistics on the Status page: http://fightaidsathome.scripps.edu/status Don't worry, we'll have no problems keeping the new jobs coming your way. I'm now preparing novel types of experiments, which will involve targeting our new dynamic models of HIV integrase. The new "eye candy" at the bottom of the Status page shows you a dynamic ensemble of our new models of the G140S/Q148H drug-resistant mutant of HIV integrase. It's one of the superbugs that we'll start screening against fairly soon. See: http://www.ncbi.nlm.nih.gov/pubmed/20096702 for a description of these targets. Experiment 33 will most likely be our first FAAH experiment devoted to the HIV integrase system. We'll be searching for totally new classes of integrase inhibitors, as a way of advancing the design of new drugs that should work against the drug-resistant mutants of HIV integrase that are already appearing in the clinics. Thank you all very much for your help, Alex L. Perryman, Ph.D. |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Thanks for the update
---------------------------------------- @Dr. Perryman: Would you please fix the pie chart for Experiment 32? It seems that it is using the one for Experiment 31 [Edit 1 times, last edit by Former Member at Mar 30, 2010 6:12:47 AM] |
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mgl_ALPerryman
FightAIDS@Home, GO Fight Against Malaria and OpenZika Scientist USA Joined: Aug 25, 2007 Post Count: 283 Status: Offline Project Badges:
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Dear Moonian,
You're welcome. And thank you very much for catching my mistake. The pie chart for Experiment 32 has now been fixed. Thanks again, Alex L. Perryman, Ph.D. |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
You're welcome, Dr. Perryman
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
There was an article on sciencedaily about Vpu protein http://www.sciencedaily.com/releases/2010/04/100408171510.htm
----------------------------------------It seems to me that if it is possible to find something that will bind tightly to that protein... and block its possibility to interact with tetherin...then we have at least a theoretical solution. I understand that it should be easy to perform it using the simulation methods and all our PCs. Maybe you already have plans for that type of experiment - please let us know :) [Edit 1 times, last edit by Former Member at Apr 22, 2010 10:50:03 AM] |
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