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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
Why is the agent called Rosetta?
Does the name have anything to do with the Rosetta Stone? |
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Former Member
Cruncher Joined: May 22, 2018 Post Count: 0 Status: Offline |
there are several Rosettas. All refer to the Rosetta stone that was in effect a stone document containing three ancient languages. Several features of the three sided document made it key in the process of cracking one of the languages. Thus computer geeks like to use the name Rosetta when they are translating one thingie into another thingie ... we tend to convert between thingies quite often in computaitonal biology ( you can think of the central dogma as translating thingies into other thingies DNA->RNA->protein).
One day several of us woke up and decided to name our companies and/or programs Rosetta. "Rosetta informatics" is a company (now part of merc) that is well known for thier pioneering work on expression analysis. "Rosetta Stone" is a method for predicting protein interactions via comparing the organisation of similar proteins in different genomes and finding domains that are seperate in one genome and fused in another, implying increased probability of interaction between the two proteins in the organism where they are not fused. "Rosetta de novo structure prediction" is what we have on the grid and was given its name by Kim Simons in 1997 or 1998. This was when I was a 1st year grad student and I started working on the code soon-after. so the Rosettas all came about at the same time... and these are just the bioinformatics rosettas... phew. |
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