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Help Cure Muscular Dystrophy Update on November 15, 2007

Juste un petit mot pour dire que Sophie a analysé une partie des données issues de la phase I. Comme nous l'espérions, l'analyse de ces données montre que l'utilisation du critère numérique que nous avons développé ces derniers mois (un papier concernant ce travail a été récemment envoyé à un journal) permet de discriminer de façon satisfaisante les partenaires protéiques. Nous n'obtenons pas une aussi bonne discrimination en intégrant JET pour le moment (JET est l'algorithme de détection phylogénétique de sites d'interactions qui doit permettre de reduire les temps de calculs du docking) mais nous devons encore travailler sur la façon d'intégrer JET. Les mois suivants seront utilisés à cette fin.

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Just a word to say that Sophie looked at a portion of the data set issued from phase 1 and she can discriminate well protein partners, as we were hoping (!), with a numerical criteria we have developed in these last months (we recently sent a paper to a journal on this work). We did not yet obtain the same good discrimination by integrating JET (the phylogenetic prediction of binding sites that will allow us to reduce the docking computation) but we know that we need to work on it. The next months will be used also for this.
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[Edit 2 times, last edit by TKH at Mar 10, 2008 1:59:47 PM]
[Nov 15, 2007 3:38:23 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Help Cure Muscular Dystrophy Update on November 15, 2008

Thank you for the update, Alessandra hugs
[Nov 15, 2007 6:40:41 PM]   Link   Report threatening or abusive post: please login first  Go to top 
JmBoullier
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Re: Help Cure Muscular Dystrophy Update on November 15, 2008

Pour quelqu'un de notre équipe c'est forcément une bonne nouvelle qui aide à attendre la suite!
Heureusement (et malheureusement aussi, du point de vue des malades) il y a d'autres ennemis intéressants à assièger avec nos machines pour garder le rythme.

Bonne continuation à votre équipe Alessandra.
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[Nov 16, 2007 10:48:57 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Help Cure Muscular Dystrophy Update on November 15, 2008

good luck on that.

we all know there is no guarantee but i hope you find something useful. smile
[Nov 17, 2007 10:51:13 PM]   Link   Report threatening or abusive post: please login first  Go to top 
crooks_uk
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smile Re: Help Cure Muscular Dystrophy Update on November 15, 2008

Many thanks for the update. And good luck for the future
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[Nov 19, 2007 8:42:41 AM]   Link   Report threatening or abusive post: please login first  Go to top 
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Re: Help Cure Muscular Dystrophy Update on November 15, 2008

Any updates/tarot card readings about HCMD Phase II? biggrin

(Also this thread came from the future apparently wink )
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[Edit 1 times, last edit by Former Member at Mar 7, 2008 3:19:32 PM]
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TKH
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Re: Help Cure Muscular Dystrophy Update on November 15, 2008

Hello esoteric17,

Alessandra has sent a note and said she will provide an update in the next couple of weeks. Thanks!

TKH
[Mar 13, 2008 1:05:43 PM]   Link   Report threatening or abusive post: please login first  Go to top 
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